Nonpsychotropic Cannabinoid Receptors Regulate Microglial Cell Migration

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

1992 • 5,504 citations

Molecular characterization of a peripheral receptor for cannabinoids

1993 • 4,950 citations

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

1990 • 4,933 citations

Microglia: a sensor for pathological events in the CNS

1996 • 4,309 citations

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

1995 • 2,837 citations

International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors

2002 • 2,707 citations

2-Arachidonoylgylcerol: A Possible Endogenous Cannabinoid Receptor Ligand in Brain

1995 • 2,122 citations

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

1994 • 1,743 citations

Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses

2001 • 1,571 citations

Formation and inactivation of endogenous cannabinoid anandamide in central neurons

1994 • 1,564 citations

Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system

1998 • 1,549 citations

Actin-Based Cell Motility and Cell Locomotion

1996 • 1,536 citations

A second endogenous cannabinoid that modulates long-term potentiation

1997 • 1,474 citations

Regulation of Cell Motility by Mitogen-activated Protein Kinase

1997 • 1,238 citations

Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice

1999 • 1,060 citations

Retrograde Inhibition of Presynaptic Calcium Influx by Endogenous Cannabinoids at Excitatory Synapses onto Purkinje Cells

2001 • 847 citations

Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors.

1995 • 838 citations

Cognitive Functioning of Long-term Heavy Cannabis Users Seeking Treatment

2002 • 785 citations

Adverse effects of cannabis

1998 • 782 citations

Dopamine activation of endogenous cannabinoid signaling in dorsal striatum

1999 • 773 citations

2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB ₁ receptor

2001 • 752 citations

An endogenous cannabinoid (2-AG) is neuroprotective after brain injury

2001 • 726 citations

SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor.

1998 • 679 citations

The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis

2000 • 632 citations

Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors

1999 • 599 citations

Dynamics of microglial activation: A confocal time-lapse analysis in hippocampal slices

2001 • 563 citations

Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands.

1996 • 555 citations

Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB2 receptor

2000 • 534 citations

Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations

2000 • 528 citations

Cannabinoids control spasticity and tremor in a multiple sclerosis model

2000 • 526 citations

Single-Molecule Speckle Analysis of Actin Filament Turnover in Lamellipodia

2002 • 478 citations

Blockade of Effects of Smoked Marijuana by the CB1-Selective Cannabinoid Receptor Antagonist SR141716

2001 • 474 citations

Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction.

1993 • 469 citations

Marijuana and medicine: assessing the science base

1999 • 411 citations

Endocannabinoids control spasticity in a multiple sclerosis model

2000 • 378 citations

Evidence That 2-Arachidonoylglycerol but Not N-Palmitoylethanolamine or Anandamide Is the Physiological Ligand for the Cannabinoid CB2 Receptor

2000 • 370 citations

Brain-immune connection: Immuno-regulatory properties of CNS-resident cells

2000 • 349 citations

Ultrastructural Localization of the CB1 Cannabinoid Receptor in μ-Opioid Receptor Patches of the Rat Caudate Putamen Nucleus

2001 • 343 citations

Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor

1993 • 338 citations

The Perceived Effects of Smoked Cannabis on Patients with Multiple Sclerosis

1997 • 326 citations

Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock

1997 • 288 citations

Signaling Pathway Associated with Stimulation of CB2 Peripheral Cannabinoid Receptor

1996 • 277 citations

Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells

1997 • 274 citations

Receptor-dependent formation of endogenous cannabinoids in cortical neurons

2001 • 240 citations

Dynamics of a Chemoattractant Receptor in Living Neutrophils during Chemotaxis

1999 • 230 citations

Marijuana and Medicine: Assessing the Science Base: A Summary of the 1999 Institute of Medicine Report

2000 • 228 citations

The central cannabinoid receptor (CB1) mediates inhibition of nitric oxide production by rat microglial cells.

1999 • 219 citations

Estrogen Receptor (ER)α and ERβ Exhibit Unique Pharmacologic Properties When Coupled to Activation of the Mitogen-Activated Protein Kinase Pathway*

2001 • 219 citations

Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia

1996 • 217 citations

Cannabinoids Reveal the Necessity of Hippocampal Neural Encoding for Short-Term Memory in Rats

2000 • 204 citations

Cloning and pharmacological characterization of the rat CB(2) cannabinoid receptor.

2000 • 199 citations

Δ9-Tetrahydrocannabinol: a novel treatment for experimental autoimmune encephalomyelitis

1989 • 197 citations

Colonisation of the developing human brain and spinal cord by microglia: a review

1999 • 192 citations

Marijuana, immunity and infection

1998 • 192 citations

Microglial-neuronal interactions in synaptic damage and recovery

1999 • 179 citations

The cannabinoid CB 1 receptor antagonist SR141716A attenuates the memory impairment produced by ? 9 -tetrahydrocannabinol or anandamide

1998 • 176 citations

Astrocytes in Culture Produce Anandamide and Other Acylethanolamides

2002 • 176 citations

Endogenous Cannabinoid Signaling

1998 • 163 citations

A comparison of the pharmacological activity in man of intravenously administered 1368-11368-11368-1, cannabinol, and cannabidiol

1973 • 156 citations

Effect of cannabinoids on spasticity and ataxia in multiple sclerosis

1989 • 130 citations

Activation of mouse microglial cells affects P2 receptor signaling

2000 • 125 citations

Suppression of experimetal autoimmune encephalomyelitis by cannabinoids

1994 • 116 citations

Assays of leukocyte locomotion and chemotaxis

1998 • 105 citations

Differential Assembly of Rat Purinergic P2X7 Receptor in Immune Cells of the Brain and Periphery

2001 • 103 citations

Regulation of Peripheral Cannabinoid Receptor CB2Phosphorylation by the Inverse Agonist SR 144528

1999 • 102 citations

Genomic and Functional Changes Induced by the Activation of the Peripheral Cannabinoid Receptor CB2 in the Promyelocytic Cells HL-60

2000 • 94 citations

Differential expression of cannabinoid CB2 receptor mRNA in mouse immune cell subpopulations and following B cell stimulation

2001 • 94 citations

A sensitive endocannabinoid assay. The simultaneous analysis of N-acylethanolamines and 2-monoacylglycerols

2000 • 78 citations

Regulation of the cAMP cascade, gene expression and immune function by cannabinoid receptors

1998 • 62 citations

Effects of two endogenous fatty acid ethanolamides on mouse vasa deferentia

1994 • 57 citations

CB ₁ Receptor Antagonist SR141716A Inhibits Ca ²⁺ -Induced Relaxation in CB ₁ Receptor-Deficient Mice

2002 • 56 citations

Stereochemical Selectivity of Methanandamides for the CB1 and CB2 Cannabinoid Receptors and Their Metabolic Stability

2001 • 51 citations

Characterization of CB1 Receptors on Rat Neuronal Cell Cultures: Binding and Functional Studies Using the Selective Receptor Antagonist SR 141716A

1997 • 37 citations

Dose‐Related Inhibition of Leukocyte Migration by Marihuana and Delta‐9‐Tetrahydrocannabinol (THC) in Vitro

1974 • 27 citations

Brain-immune connection: Immuno-regulatory properties of CNS-resident cells

2000 • 24 citations

Microglial–neuronal interactions in synaptic damage and recovery

1999 • 18 citations

Colonisation of the developing human brain and spinal cord by microglia: a review

1999 • 15 citations

Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia

1996 • 15 citations

Analyzer Workshop on the Treatment of Parkinson's Disease

1997 • 9 citations