Studies on the release by somatic stimulation from rat and cat spinal cord of active materials which displace dihydromorphine in an opiate-binding assay

Identification of two related pentapeptides from the brain with potent opiate agonist activity

1975 • 3,780 citations

Cloning and sequence analysis of cDNA for bovine adrenal preproenkephalin

1982 • 928 citations

Dynorphin-(1-13), an extraordinarily potent opioid peptide.

1979 • 852 citations

Immunohistochemical localization of enkephalin in rat brain and spinal cord

1978 • 814 citations

Immunohistochemical studies using antibodies to leucine-enkephalin: Initial observations on the nervous system of the rat

1976 • 767 citations

The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice

1980 • 705 citations

Narcotic analgetics: CNS sites and mechanisms of action as revealed by intracerebral injection techniques

1977 • 656 citations

Molecular cloning establishes proenkephalin as precursor of enkephalin-containing peptides

1982 • 621 citations

Spinal opiate analgesia: Characteristics and principles of action

1981 • 552 citations

Studies on the direct spinal action of narcotics in the production of analgesia in the rat.

1977 • 543 citations

Increased Cerebrospinal Fluid Levels of Endorphins after Electro‐Acupuncture

1977 • 452 citations

Brain Stem Control of Spinal Mechanisms

1982 • 424 citations

Selective reduction by noradrenaline and 5-hydroxytryptamine of nociceptive responses of cat dorsal horn neurones

1978 • 332 citations

Spinal noradrenergic terminal system mediates antinociception

1980 • 317 citations

Morphine-like ligand for opiate receptors in human CSF

1975 • 281 citations

Microinjection of morphine into the periaqueductal gray evokes the release of serotonin from spinal cord

1979 • 234 citations

The electron microscopic localization of methionine-enkephalin within the superficial layers (I and II) of the spinal cord

1980 • 234 citations

SUPPRESSION OF TRANSMISSION OF NOCICEPTIVE IMPULSES BY MORPHINE: SELECTIVE EFFECTS OF MORPHINE ADMINISTERED IN THE REGION OF THE SUBSTANTIA GELATINOSA

1977 • 195 citations

Immunoreactive dynorphin in mammalian spinal cord and dorsal root ganglia.

1981 • 182 citations

Factors governing release of methionine enkephalin-like immunoreactivity from mesencephalon and spinal cord of the cat in vivo.

1981 • 170 citations

Monoamine release from cat spinal cord by somatic stimuli: an intrinsic modulatory system.

1981 • 160 citations

ENHANCEMENT OF A NOCICEPTIVE REACTION BY OPIOID ANTAGONISTS IN MICE

1978 • 127 citations

Analgesia and hyperalgesia produced in the rat by intrathecal naloxone

1980 • 122 citations

Alterations in rat central nervous system endorphins following transauricular electroacupuncture

1981 • 108 citations

Opioid hexapeptides and heptapeptides in adrenal medulla and brain possible implications on the biosynthesis of enkephalins

1980 • 87 citations

The effect of the narcotic antagonists naloxone, naltrexone and nalorphine on spinal cord c-fiber reflexes evoked by electrical stimulation or radiant heat

1977 • 74 citations

Zone electrophoresis in columns of agarose suspensions

1963 • 72 citations

Naloxone excites nociceptive units in the lumbar dorsal horn of the spinal cat

1979 • 68 citations

Increased levels of met-enkephalin-like material in the CSF of anaesthetized cats after tooth pulp stimulation

1982 • 60 citations

Characterization of electrophoretically separable endorphins in human CSF

1983 • 56 citations

Inhibition by etorphine of the discharge of dorsal horn neurons: Effects on the neuronal response to both high- and low-threshold sensory input in the decerebrate spinal cat

1978 • 50 citations

Immunocytochemical localization of ß-endorphin (lipotropin c-fragment) in the developing rat spinal cord and hypothalamus

1982 • 47 citations

Effects of thiorphan on the antinociceptive actions of intrathecal [D-Ala2,Met5]enkephalin

1982 • 46 citations

Enkephalin levels decrease in rat striatum during morphine abstinence

1979 • 37 citations

Effect of Lissauer tract stimulation on activity in dorsal roots and in ventral roots

1978 • 36 citations

Radioreceptor assay of methionine-enkephalin-like substance in human cerebrospinal fluid

1980 • 19 citations

RELEASE OF ENDOGENOUS OPIOIDS FROM SPINAL CORD IN VIVO FOLLOWING SCIATIC NERVE STIMULATION

1981 • 4 citations