Jun Kinases Are Rapidly Activated by Cholecystokinin in Rat Pancreas both in Vitro and in Vivo

Physiology of the Gastrointestinal Tract

2006 • 4,704 citations

The MAPK signaling cascade

1995 • 3,300 citations

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

1995 • 2,723 citations

The stress-activated protein kinase subfamily of c-Jun kinases

1994 • 2,616 citations

The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases

1995 • 2,441 citations

Physiology of the Gastrointestinal Tract.

1987 • 1,948 citations

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

1993 • 1,902 citations

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

1991 • 1,779 citations

The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

1995 • 1,653 citations

Independent Human MAP-Kinase Signal Transduction Pathways Defined by MEK and MKK Isoforms

1995 • 1,562 citations

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1995 • 1,499 citations

Transcription Factor ATF2 Regulation by the JNK Signal Transduction Pathway

1995 • 1,453 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

Parallel signal processing among mammalian MAPKs

1995 • 1,015 citations

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation.

1993 • 992 citations

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

1994 • 978 citations

MAPKs: new JNK expands the group

1994 • 949 citations

Integration of MAP Kinase Signal Transduction Pathways at the Serum Response Element

1995 • 935 citations

JNK is involved in signal integration during costimulation of T lymphocytes

1994 • 929 citations

Identification of a Dual Specificity Kinase That Activates the Jun Kinases and p38-Mpk2

1995 • 775 citations

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

1994 • 706 citations

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation.

1994 • 639 citations

ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents.

1995 • 603 citations

An Osmosensing Signal Transduction Pathway in Mammalian Cells

1994 • 584 citations

Acute interstitial pancreatitis in the rat induced by excessive doses of a pancreatic secretagogue

1977 • 571 citations

A sensitive method for detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel

1989 • 466 citations

c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases.

1994 • 463 citations

Signal transduction by tumor necrosis factor mediated by JNK protein kinases.

1994 • 456 citations

Differential Activation of Mitogen-Activated Protein Kinases by H ₂ O ₂ and O ₂ ⁻ in Vascular Smooth Muscle Cells

1995 • 416 citations

Anisomycin-activated protein kinases p45 and p55 but not mitogen-activated protein kinases ERK-1 and -2 are implicated in the induction of c-fos and c-jun.

1994 • 296 citations

The stress-activated protein kinases are major c-Jun amino-terminal kinases activated by ischemia and reperfusion

1994 • 266 citations

p53 Is Phosphorylated in Vitro and in Vivo by an Ultraviolet Radiation-induced Protein Kinase Characteristic of the c-Jun Kinase, JNK1

1995 • 256 citations

Transforming G Protein-coupled Receptors Potently Activate JNK (SAPK)

1995 • 211 citations

Characterization of 45‐kDa/54‐kDa HSP27 Kinase, a Stress‐Sensitive Kinase Which may Activate the Phosphorylation‐Dependent Protective Function of Mammalian 27‐kDa Heat‐shock Protein HSP27

1995 • 203 citations

Activation of Jun Kinase/Stress-activated Protein Kinase by GTPase-deficient Mutants of Gα12 and Gα13

1995 • 178 citations

Activation of Jun kinase is an early event in hepatic regeneration.

1995 • 150 citations

Hormonal stimulation in the exocrine pancreas results in coordinate and anticoordinate regulation of protein synthesis.

1984 • 132 citations

Evidence for Multiple Activators for Stress-activated Protein Kinases/c-Jun Amino-terminal Kinases.

1995 • 114 citations

Chromatin conformation of yeast centromeres.

1984 • 96 citations

Ionizing Radiation Stimulates a Grb2-mediated Association of the Stress-activated Protein Kinase with Phosphatidylinositol 3-Kinase

1995 • 74 citations

Loss of suppression of GSH synthesis at low cell density in primary cultures of rat hepatocytes

1992 • 68 citations

The role of oxygen radicals in experimental acute pancreatitis

1992 • 52 citations