Overproduction and dissection of proteins by the expression-cassette polymerase chain reaction.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Current protocols in molecular biology

1988 • 7,584 citations

A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes.

1985 • 3,185 citations

The Immunoglobulin Superfamily—Domains for Cell Surface Recognition

1988 • 2,237 citations

Gene organization and primary structure of a ribosomal RNA operon from Escherichia coli

1981 • 1,732 citations

Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli.

1988 • 1,536 citations

Single-Chain Antigen-Binding Proteins

1988 • 1,450 citations

A receptor for the immuno-suppressant FK506 is a cis–trans peptidyl-prolyl isomerase

1989 • 1,376 citations

MECHANISM AND CONTROL OF TRANSCRIPTION INITIATION IN PROKARYOTES

1985 • 1,012 citations

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

1989 • 1,010 citations

Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli

1989 • 989 citations

Binding of HTLV-III/LAV to T4 ⁺ T Cells by a Complex of the 110K Viral Protein and the T4 Molecule

1986 • 988 citations

Assembly of a Functional Immunoglobulin F _v Fragment in Escherichia coli

1988 • 973 citations

Interaction between CD4 and class II MHC molecules mediates cell adhesion

1987 • 823 citations

Generation of a Large Combinatorial Library of the Immunoglobulin Repertoire in Phage Lambda

1989 • 810 citations

Vectors bearing a hybrid trp-lac promoter useful for regulated expression of cloned genes in Escherichia coli

1983 • 810 citations

T Cell Subsets and the Recognition of MHC Class

1983 • 702 citations

POSTTRANSCRIPTIONAL REGULATORY MECHANISMS IN ESCHERICHIA COLI

1988 • 670 citations

The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family

1985 • 669 citations

Designing CD4 immunoadhesins for AIDS therapy

1989 • 612 citations

Escherichia coli Secretion of an Active Chimeric Antibody Fragment

1988 • 575 citations

soluble form of CD4 (T4) protein inhibits AIDS virus infection

1988 • 530 citations

PCR Technology: Principles and Applications for DNA Amplification

1990 • 512 citations

Blocking of HIV-1 Infectivity by a Soluble, Secreted Form of the CD4 Antigen

1987 • 485 citations

HIV infection is blocked in vitro by recombinant soluble CD4

1988 • 446 citations

A soluble CD4 protein selectively inhibits HIV replication and syncytium formation

1988 • 425 citations

A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin

1989 • 420 citations

Soluble CD4 molecules neutralize human immunodeficiency virus type 1

1988 • 403 citations

A practical guide to molecular cloning

1987 • 360 citations

Identification of the residues in human CD4 critical for the binding of HIV

1989 • 357 citations

Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen

1987 • 348 citations

Genomic Amplification with Transcript Sequencing

1988 • 324 citations

Structure-function relationships of the complement components

1989 • 311 citations

Mutations which alter the function of the signal sequence of the maltose binding protein of Escherichia coli

1980 • 268 citations

Complementary DNA for human T-cell cyclophilin.

1987 • 268 citations

Selective killing of HIV-infected cells by recombinant human CD4-Pseudomonas exotoxin hybrid protein

1988 • 253 citations

The functional role of ribosomal RNA in protein synthesis

1989 • 238 citations

Highly efficient neutralization of HIV with recombinant CD4-immunoglobulin molecules

1989 • 217 citations

Viral receptors of the immunoglobulin superfamily

1989 • 178 citations

Generation of antibody activity from immunoglobulin polypeptide chains produced in Escherichia coli.

1984 • 167 citations

Assembly of functional antibodies from immunoglobulin heavy and light chains synthesised inE. coli

1984 • 165 citations

Peptide and nucleotide sequences of rat CD4 (W3/25) antigen: evidence for derivation from a structure with four immunoglobulin-related domains.

1987 • 157 citations

Structure and expression of the human and mouse T4 genes.

1987 • 155 citations

A soluble recombinant polypeptide comprising the amino-terminal half of the extracellular region of the CD4 molecule contains an active binding site for human immunodeficiency virus.

1988 • 120 citations

Targeted random mutagenesis: the use of ambiguously synthesized oligonucleotides to mutagenize sequences immediately 5‘ of an ATG initiation codon

1983 • 112 citations

Topobiology

1989 • 98 citations

Class II MHC molecules and the HIV gp 120 envelope protein interact with functionally distinct regions of the CD4 molecule.

1989 • 76 citations

RNA amplification with transcript sequencing (RAWTS)

1988 • 46 citations

A 113-Amino Acid Fragment of CD4 Produced in Escherichia Coli Blocks Human Immunodeficiency Virus-induced Cell Fusion

1989 • 40 citations

A hybrid promoter and portable Shine-Dalgarno regions of Escherichia coli.

1983 • 14 citations