Programmed cell death in invertebrates

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1995 • 4,003 citations

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1994 • 2,575 citations

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme

1993 • 2,484 citations

Mechanisms and Functions of Cell Death

1991 • 2,061 citations

Genetic control of programmed cell death in the nematode C. elegans

1986 • 1,790 citations

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2

1994 • 1,145 citations

Expression of baculovirus P35 prevents cell death in Drosophila

1994 • 1,037 citations

Genetic Control of Programmed Cell Death in Drosophila

1994 • 1,028 citations

Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme

1992 • 981 citations

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

1992 • 889 citations

Prevention of Apoptosis by a Baculovirus Gene During Infection of Insect Cells

1991 • 810 citations

An evolutionary perspective on apoptosis

1994 • 758 citations

Programmed cell death during Drosophila embryogenesis

1993 • 710 citations

The head involution defective gene of Drosophila melanogaster functions in programmed cell death.

1995 • 685 citations

Inhibition of ICE Family Proteases by Baculovirus Antiapoptotic Protein p35

1995 • 645 citations

Prevention of Vertebrate Neuronal Death by the crmA Gene

1994 • 618 citations

Prevention of Programmed Cell Death in Caenorhabditis elegans by Human bcl-2

1992 • 608 citations

Fas- and Tumor Necrosis Factor-induced Apoptosis Is Inhibited by the Poxvirus crmA Gene Product

1995 • 604 citations

Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein

1995 • 467 citations

Programmed cell death in Caenorhabditis elegans

1994 • 379 citations

The Baculovirus p35 Protein Inhibits Fas- and Tumor Necrosis Factor-induced Apoptosis

1995 • 366 citations

Programmed cell death in Dictyostelium

1994 • 284 citations

Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells.

1993 • 223 citations

Baculovirus p35 prevents developmentally programmed cell death and rescues a ced-9 mutant in the nematode Caenorhabditis elegans.

1994 • 204 citations

Expression of the Baculovirus p35 Gene Inhibits Mammalian Neural Cell Death

1993 • 194 citations

Activation of C. elegans cell death protein CED-9 by an ammo-acid substitution in a domain conserved in Bcl-2

1994 • 177 citations

Overexpressed full-length human BCL2 extends the survival of baculovirus-infected Sf9 insect cells.

1992 • 169 citations

Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation.

1995 • 140 citations

The essential OST2 gene encodes the 16-kD subunit of the yeast oligosaccharyltransferase, a highly conserved protein expressed in diverse eukaryotic organisms.

1995 • 122 citations

Programmed nuclear death: Apoptotic-like degradation of specific nuclei in conjugating Tetrahymena

1992 • 117 citations

dad-1, an endogenous programmed cell death suppressor in Caenorhabditis elegans and vertebrates.

1995 • 113 citations

The ins and outs of programmed cell death duringC. elegansdevelopment

1994 • 100 citations

Embryonic head involution and rotation of male terminalia require the Drosophila locus head involution defective.

1991 • 97 citations

Molecular genetics of cell death in the nematode Caenorhabditis elegans

1992 • 77 citations

Programmed Cell Death: A rich harvest

1994 • 14 citations