IL-10: Evolving concepts☆☆☆★★★

Interleukin-10-deficient mice develop chronic enterocolitis

1993 • 4,225 citations

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

1989 • 2,771 citations

Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production.

1993 • 945 citations

IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression.

1993 • 862 citations

Models of T cell anergy: is there a common molecular mechanism?

1996 • 575 citations

Interleukin-10 regulation in normal subjects and patients with asthma

1996 • 498 citations

IL-10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells.

1992 • 417 citations

Predominant role of tumor necrosis factor-alpha in human monocyte IL-10 synthesis.

1993 • 386 citations

Interleukin-10 Is a Natural Suppressor of Cytokine Production and Inflammation in a Murine Model of Allergic Bronchopulmonary Aspergillosis

1997 • 324 citations

Insect venom immunotherapy induces interleukin‐10 production and a Th2‐to‐Th1 shift, and changes surface marker expression in venom‐allergic subjects

1997 • 287 citations

Interleukin-10 inhibits antigen-induced cellular recruitment into the airways of sensitized mice.

1995 • 283 citations

Nasal Immunotherapy in Weed-Induced Allergic Rhinitis

1997 • 45 citations