Receptors for Protons or Lipid Messengers or Both?
Data up to Jan 2025
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Abstract
References (35)
A proton-gated cation channel involved in acid-sensing
1997 • 1,314 citations
Proton-sensing G-protein-coupled receptors
2003 • 667 citations
Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents
2006 • 626 citations
Lysophospholipids--Receptor Revelations
2001 • 539 citations
Lysophosphatidylcholine as a Ligand for the Immunoregulatory Receptor G2A
2001 • 329 citations
Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1
2000 • 291 citations
Acidosis Inhibits Bone Formation by Osteoblasts In Vitro by Preventing Mineralization
2005 • 244 citations
Sphingosylphosphorylcholine and Lysophosphatidylcholine Are Ligands for the G Protein-coupled Receptor GPR4
2001 • 242 citations
G2A Is a Proton-sensing G-protein-coupled Receptor Antagonized by Lysophosphatidylcholine
2004 • 241 citations
TDAG8 Is a Proton-sensing and Psychosine-sensitive G-protein-coupled Receptor
2004 • 241 citations
Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells
2005 • 199 citations
Regulation of bone cell function by acid–base balance
2003 • 191 citations
Identification of T Cell Death-associated Gene 8 (TDAG8) as a Novel Acid Sensing G-protein-coupled Receptor
2004 • 183 citations
Identification of a Molecular Target of Psychosine and Its Role in Globoid Cell Formation
2001 • 180 citations
Proton-sensing and lysolipid-sensitive G-protein-coupled receptors: A novel type of multi-functional receptors
2005 • 180 citations
Identification of 9-Hydroxyoctadecadienoic Acid and Other Oxidized Free Fatty Acids as Ligands of the G Protein-coupled Receptor G2A
2005 • 173 citations
Convergent signaling by acidosis and receptor activator of NF-κB ligand (RANKL) on the calcium/calcineurin/NFAT pathway in osteoclasts
2005 • 155 citations
A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M
1998 • 144 citations
Sphingosylphosphorylcholine—biological functions and mechanisms of action
2002 • 132 citations
Identification of a Putative G Protein-Coupled Receptor Induced during Activation-Induced Apoptosis of T Cells
1996 • 109 citations
Metabolic Acidosis Stimulates RANKL RNA Expression in Bone Through a Cyclo-oxygenase-Dependent Mechanism
2003 • 99 citations
Identification of Human OGR1, a Novel G Protein-Coupled Receptor That Maps to Chromosome 14
1996 • 98 citations
Prostaglandin I2 Production and cAMP Accumulation in Response to Acidic Extracellular pH through OGR1 in Human Aortic Smooth Muscle Cells
2005 • 94 citations
Lysophospholipid Receptors as Potential Drug Targets in Tissue Transplantation and Autoimmune Diseases
2005 • 79 citations
GPR4 plays a critical role in endothelial cell function and mediates the effects of sphingosylphosphorylcholine
2005 • 77 citations
pH and smooth muscle
1997 • 77 citations
Normal Immune Development and Glucocorticoid-Induced Thymocyte Apoptosis in Mice Deficient for the T-Cell Death-Associated Gene 8 Receptor
2005 • 73 citations
Central chemoreception 2005: A brief review
2006 • 70 citations
Sphingosylphosphorylcholine Antagonizes Proton-Sensing Ovarian Cancer G-Protein-Coupled Receptor 1 (OGR1)-Mediated Inositol Phosphate Production and cAMP Accumulation
2005 • 68 citations
Inflammatory stress increases receptor for lysophosphatidylcholine in human microvascular endothelial cells
2003 • 63 citations
Isolation of a Novel G Protein-Coupled Receptor (GPR4) Localized to Chromosome 19q13.3
1995 • 49 citations
Cloning, sequencing and tissue distribution of two related G protein‐coupled receptor candidates expressed prominently in human lung tissue
1995 • 35 citations
Two ligands for a GPCR, proton vs lysolipid1
2005 • 34 citations
Mechanisms of action of pH-induced effects on vascular smooth muscle
2004 • 33 citations
Direct observation of G-protein binding to the human δ-opioid receptor using plasmon-waveguide resonance spectroscopy. VOLUME 278 (2003) PAGES 48890-48897
2005 • 6 citations