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Receptors for Protons or Lipid Messengers or Both?

Data up to Jan 2025

Published2006
Citations143
References35

Total Citations Per Year

Abstract

References (35)

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Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells

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Regulation of bone cell function by acid–base balance

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Identification of T Cell Death-associated Gene 8 (TDAG8) as a Novel Acid Sensing G-protein-coupled Receptor

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Identification of a Molecular Target of Psychosine and Its Role in Globoid Cell Formation

2001 • 180 citations

Proton-sensing and lysolipid-sensitive G-protein-coupled receptors: A novel type of multi-functional receptors

2005 • 180 citations

Identification of 9-Hydroxyoctadecadienoic Acid and Other Oxidized Free Fatty Acids as Ligands of the G Protein-coupled Receptor G2A

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A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M

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Metabolic Acidosis Stimulates RANKL RNA Expression in Bone Through a Cyclo-oxygenase-Dependent Mechanism

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Identification of Human OGR1, a Novel G Protein-Coupled Receptor That Maps to Chromosome 14

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Prostaglandin I2 Production and cAMP Accumulation in Response to Acidic Extracellular pH through OGR1 in Human Aortic Smooth Muscle Cells

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Lysophospholipid Receptors as Potential Drug Targets in Tissue Transplantation and Autoimmune Diseases

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GPR4 plays a critical role in endothelial cell function and mediates the effects of sphingosylphosphorylcholine

2005 • 77 citations

pH and smooth muscle

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Normal Immune Development and Glucocorticoid-Induced Thymocyte Apoptosis in Mice Deficient for the T-Cell Death-Associated Gene 8 Receptor

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Sphingosylphosphorylcholine Antagonizes Proton-Sensing Ovarian Cancer G-Protein-Coupled Receptor 1 (OGR1)-Mediated Inositol Phosphate Production and cAMP Accumulation

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Inflammatory stress increases receptor for lysophosphatidylcholine in human microvascular endothelial cells

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Isolation of a Novel G Protein-Coupled Receptor (GPR4) Localized to Chromosome 19q13.3

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Cloning, sequencing and tissue distribution of two related G protein‐coupled receptor candidates expressed prominently in human lung tissue

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Two ligands for a GPCR, proton vs lysolipid1

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Mechanisms of action of pH-induced effects on vascular smooth muscle

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