Sphingosylphosphorylcholine and Lysophosphatidylcholine Are Ligands for the G Protein-coupled Receptor GPR4

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Atherosclerosis

2000 • 4,558 citations

Endocytosis

1997 • 1,263 citations

Characterization of a Novel Subtype of Human G Protein-coupled Receptor for Lysophosphatidic Acid

1998 • 535 citations

Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1‐phosphate

1998 • 516 citations

Regulatory mechanisms that modulate signalling by G-protein-coupled receptors

1997 • 502 citations

Bioactive Lysophospholipids and Their G Protein-Coupled Receptors

1999 • 412 citations

G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins

1996 • 332 citations

Lysophosphatidylcholine as a Ligand for the Immunoregulatory Receptor G2A

2001 • 329 citations

Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1

2000 • 291 citations

Lysophosphatidic acid, but not phosphatidic acid, is a potent Ca2(+)-mobilizing stimulus for fibroblasts. Evidence for an extracellular site of action.

1990 • 264 citations

G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins

1996 • 264 citations

Oxidatively modified low density lipoprotein is a chemoattractant for human T lymphocytes.

1993 • 255 citations

Characterization of plasma unsaturated lysophosphatidylcholines in human and rat

1999 • 233 citations

Sphingolipid metabolites: Members of a new class of lipid second messengers

1995 • 226 citations

Identification of a Molecular Target of Psychosine and Its Role in Globoid Cell Formation

2001 • 180 citations

Lysophosphatidylcholine (LPC) induces proinflammatory cytokines by a platelet-activating factor (PAF) receptor-dependent mechanism

1999 • 177 citations

Elevated levels and altered fatty acid composition of plasma lysophosphatidlycholine(lysoPC) in ovarian cancer patients

1997 • 148 citations

A DNA damage and stress inducible G protein-coupled receptor blocks cells in G₂/M

1998 • 144 citations

Induction by Lysophosphatidylcholine, a Major Phospholipid Component of Atherogenic Lipoproteins, of Human Coronary Artery Smooth Muscle Cell Migration

1998 • 128 citations

Transduction of intracellular calcium signals through G protein-mediated activation of phospholipase C by recombinant sphingosine 1-phosphate receptors.

1999 • 123 citations

Signaling pathways for sphingosylphosphorylcholine-mediated mitogenesis in Swiss 3T3 fibroblasts.

1993 • 117 citations

Identification of a Putative G Protein-Coupled Receptor Induced during Activation-Induced Apoptosis of T Cells

1996 • 109 citations

Role of lysophosphatidylcholine in the inhibition of endothelial cell motility by oxidized low density lipoprotein.

1996 • 109 citations

Identification of Human OGR1, a Novel G Protein-Coupled Receptor That Maps to Chromosome 14

1996 • 98 citations

Isolation of Three Novel Human Genes Encoding G Protein-Coupled Receptors

1995 • 97 citations

Lysophosphatidyl Choline, a Chemotactic Factor for Monocytes/T-Lymphocytes Is Elevated in Endometriosis

1998 • 96 citations

Effect of lysophosphatidylcholine on transmembrane signal transduction.

1998 • 95 citations

Regulation of cell growth by oxidized LDL

2000 • 93 citations

The Significance of Plasma Lysophospholipids in Patients with Renal Failure on Hemodialysis.

1998 • 85 citations

Direct genetic demonstration of Gα13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement

2000 • 68 citations

Cloning, Characterization, and Mapping of Human Homolog of Mouse T-Cell Death-Associated Gene

1998 • 61 citations

Lysophosphatidylcholine stimulates phospholipase D activity in mouse peritoneal macrophages

1999 • 56 citations

Immunological mechanisms in atherosclerosis

1995 • 54 citations

Isolation of a Novel G Protein-Coupled Receptor (GPR4) Localized to Chromosome 19q13.3

1995 • 49 citations

Cloning, sequencing and tissue distribution of two related G protein‐coupled receptor candidates expressed prominently in human lung tissue

1995 • 35 citations

Stimulatory and inhibitory actions of lysophosphatidylcholine, depending on its fatty acid residue, on the phospholipase C/Ca2+ system in HL-60 leukaemia cells

1998 • 25 citations

Serum proteins neutralize the toxic effect of lysophosphatidyl choline

1982 • 18 citations

Mechanism of Endothelium-Dependent Vasorelaxation Evoked by Lysophosphatidylcholine.

1998 • 9 citations

Deleted Work

1955 • 0 citations