Inflammatory stress increases receptor for lysophosphatidylcholine in human microvascular endothelial cells

HMEC-1: Establishment of an Immortalized Human Microvascular Endothelial Cell Line

1992 • 1,258 citations

Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells.

1992 • 828 citations

Selective expression of adhesion molecules on human brain microvascular endothelial cells

1997 • 368 citations

Lysophosphatidylcholine as a Ligand for the Immunoregulatory Receptor G2A

2001 • 329 citations

Sphingosylphosphorylcholine and Lysophosphatidylcholine Are Ligands for the G Protein-coupled Receptor GPR4

2001 • 242 citations

A DNA damage and stress inducible G protein-coupled receptor blocks cells in G₂/M

1998 • 144 citations

Expression of PKA inhibitor (PKI) gene abolishes cAMPmediated protection to endothelial barrier dysfunction

1999 • 141 citations

Induction by Lysophosphatidylcholine, a Major Phospholipid Component of Atherogenic Lipoproteins, of Human Coronary Artery Smooth Muscle Cell Migration

1998 • 128 citations

Lysophosphatidylcholine Promotes P-Selectin Expression in Platelets and Endothelial Cells

1996 • 127 citations

Lysophosphatidylcholine induces the production of IL-1β by human monocytes

1998 • 125 citations

Lysophosphatidylcholine in oxidized low-density lipoprotein increases endothelial susceptibility to polymorphonuclear leukocyte-induced endothelial dysfunction in porcine coronary arteries. Role of protein kinase C.

1994 • 123 citations

Lysophosphatidylcholine Stimulates the Release of Arachidonic Acid in Human Endothelial Cells

1998 • 112 citations

Lysophosphatidylcholine increases the secretion of matrix metalloproteinase 2 through the activation of NADH/NADPH oxidase in cultured aortic endothelial cells

2001 • 111 citations

Isolation of Three Novel Human Genes Encoding G Protein-Coupled Receptors

1995 • 97 citations

Lysophosphatidylcholine stimulates the expression and production of MCP-1 by human vascular endothelial cells

1996 • 87 citations

Activation of ICAM-1 promoter by lysophosphatidylcholine: Possible involvement of protein tyrosine kinases

1997 • 79 citations

Lysophosphatidylcholine causes Ca2+ influx, enhanced DNA synthesis and cytotoxicity in cultured vascular smooth muscle cells

1995 • 68 citations

Lysophosphatidylcholine Activates Extracellular Signal-Regulated Kinases 1/2 Through Reactive Oxygen Species in Rat Vascular Smooth Muscle Cells

2002 • 66 citations

Lysophosphatidylcholine Enhances Superoxide Anions Production via Endothelial NADH/NADPH Oxidase

2000 • 63 citations

Changes of Gene Expression by Lysophosphatidylcholine in Vascular Endothelial Cells: 12 Up-Regulated Distinct Genes Including 5 Cell Growth-Related, 3 Thrombosis-Related, and 4 Others

1998 • 51 citations

Burst production of superoxide anion in human endothelial cells by lysophosphatidylcholine

1999 • 50 citations

Isolation of a Novel G Protein-Coupled Receptor (GPR4) Localized to Chromosome 19q13.3

1995 • 49 citations

Lysophosphatidylcholine generates superoxide anions through activation of phosphatidylinositol 3‐kinase in human neutrophils

1998 • 45 citations

Lysophosphatidylcholine activates mitogen-activated protein kinases by a tyrosine kinase-dependent pathway in bovine aortic endothelial cells

1999 • 38 citations

Lysophosphatidylcholine Induces Early Growth Response Factor-1 Expression and Activates the Core Promoter of PDGF-A Chain in Vascular Endothelial Cells

2001 • 27 citations

Vascular endothelial cells express isoforms of protein kinase A inhibitor

2002 • 26 citations