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How selective is GR 43175? Interactions with functional 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors

Data up to Jan 2025

Published1989
Citations116
References19

Total Citations Per Year

Abstract

References (19)

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

1980 • 1,579 citations

Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine

1986 • 1,255 citations

The Classification of Adrenoceptors (Adrenergic Receptors). An Evaluation from the Standpoint of Receptor Theory

1972 • 812 citations

Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: Radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (−)[125I]iodocyanopindolol, [3H]mesulergine and [3H]Ketanserin

1985 • 581 citations

Serotonin receptors in the human brain. I. Characterization and autoradiographic localization of 5-HT1A recognition sites. Apparent absence of 5-HT1B recognition sites

1986 • 386 citations

5-Hydroxytryptamine Receptor Subtypes

1988 • 361 citations

GR43175, a selective agonist for the 5‐HT1‐like receptor in dog isolated saphenous vein

1988 • 305 citations

Molecular pharmacology and biology of 5-HT1C receptors

1988 • 237 citations

POSSIBLE BENEFIT OF GR43175, A NOVEL 5-HT1-LIKE RECEPTOR AGONIST, FOR THE ACUTE TREATMENT OF SEVERE MIGRAINE

1988 • 186 citations

Molecular pharmacology of 5-HT1D recognition sites: Radioligand binding studies in human, pig and calf brain membranes

1988 • 177 citations

5-HT1B receptors are negatively coupled with adenylate cyclase in rat substantia nigra

1988 • 160 citations

Centrally acting hypotensive agents with affinity for 5‐HT1A binding sites inhibit forskolin‐stimulated adenylate cyclase activity in calf hippocampus

1988 • 151 citations

Characterization of 5‐HT receptors mediating contraction of canine and primate basilar artery by use of GR43175, a selective 5‐HT1‐like receptor agonist

1989 • 133 citations

The 5-hydroxytryptamine 5-HT1D receptor subtype is negatively coupled to adenylate cyclase in calf substantia nigra

1988 • 126 citations

Visualization of a novel serotonin recognition site (5-HT1D) in the human brain by autoradiography

1988 • 105 citations

5-HT1C receptor-mediated stimulation of inositol phosphate production in pig choroid plexus

1989 • 102 citations

Species variations in RU 24969 interactions with non-5-HT1A binding sites

1986 • 98 citations

The pharmacological properties of the presynaptic serotonin autoreceptor in the pig brain cortex conform to the 5-HT1D receptor subtype

1989 • 97 citations

A pharmacological analysis of the 5-HT receptor mediating inhibition of 5-HT release in the guinea-pig frontal cortex

1988 • 87 citations

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How selective is GR 43175? Interactions with functional 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D… (1989) – Naunyn-Schmiedeberg s Archives of Pharmacology | Metascience Observatory Explorer