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Chemical synaptic transmission in the cochlea

Data up to Jan 2025

Published1995
Citations262
References241

Total Citations Per Year

Abstract

References (241)

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Changes in Endolymphatic Potential and Crossed Olivocochlear Bundle Stimulation Alter Cochlear Mechanics

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The cochlear frequency map for the cat: Labeling auditory-nerve fibers of known characteristic frequency

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Afferent and efferent innervation of the cat cochlea: Quantitative analysis with light and electron microscopy

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Morphological differences among radial afferent fibers in the cat cochlea: An electron-microscopic study of serial sections

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Low‐frequency characteristics of intracellularly recorded receptor potentials in guinea‐pig cochlear hair cells.

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Direct measurement of the action of acetylcholine on isolated outer hair cells of the guinea pig cochlea

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Cholinergic inhibition of short (outer) hair cells of the chick's cochlea.

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Functional significance of dendritic swelling after loud sounds in the guinea pig cochlea

1983 • 244 citations

Excitatory amino acid antagonists

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Effect of Anoxia on Cochlear Potentials

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Effects of contralateral sound on auditory-nerve responses. I. Contributions of cochlear efferents

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Cochlear receptor development in the rat with emphasis on synaptogenesis

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Frequency‐dependent N‐methyl‐D‐aspartate receptor‐mediated synaptic transmission in rat hippocampus.

1988 • 224 citations

Cochlear mechanics: Implications of electrophysiological and acoustical observations

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Acoustic distortion products can be used to monitor the effects of chronic gentamicin treatment

1989 • 218 citations

Production of cochlear potentials by inner and outer hair cells

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Horseradish peroxidase injection of physiologically characterized afferent and efferent neurones in the guinea pig spiral ganglion

1984 • 216 citations

Cholinergic inhibition of short (outer) hair cells of the chick's cochlea

1992 • 212 citations

Excitatory amino acid antagonists protect cochlear auditory neurons from excitotoxicity

1994 • 211 citations

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Molecular properties and functions of insect acetylcholine receptors

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Alpha 5, alpha 3, and non-alpha 3. Three clustered avian genes encoding neuronal nicotinic acetylcholine receptor-related subunits.

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Effect of contralateral sound stimulation on the distortion product 2F1−F2: Evidence that the medial efferent system is involved

1990 • 186 citations

Active and nonlinear cochlear biomechanics and the role of outer-hair-cell subsystem in the mammalian auditory system

1986 • 183 citations

Interactions between entorhinal axons and target hippocampal neurons: A role for glutamate in the development of hippocampal circuitry

1988 • 183 citations

Neurobiology of Hearing: The Cochlea

1986 • 179 citations

Kainic acid selectively alters auditory dendrites connected with cochlear inner hair cells

1985 • 177 citations

Selective attention modifies the active micromechanical properties of the cochlea

1988 • 175 citations

Acoustic distortion products in rabbit ear canal. I. Basic features and physiological vulnerability

1987 • 173 citations

Antimasking effects of the olivocochlear reflex. I. Enhancement of compound action potentials to masked tones

1993 • 173 citations

Auditory Physiology and Perception

1992 • 172 citations

Control of intracellular calcium by ATP in isolated outer hair cells of the guinea‐pig cochlea.

1990 • 170 citations

Expression of AMPA, kainate, and NMDA receptor subunits in cochlear and vestibular ganglia

1995 • 170 citations

N-methyl-D-aspartate receptors are transiently expressed in the developing spinal cord ventral horn.

1992 • 169 citations

Neurotransmission in the inner ear

1986 • 169 citations

Sound-induced motility of isolated cochlear outer hair cells is frequency-specific

1989 • 166 citations

Tinnitus in noise-induced hearing loss

1985 • 166 citations

The response of hair cells in the basal turn of the guinea‐pig cochlea to tones.

1987 • 163 citations

Plasticity in dendrites shown by continuous GABA administration in superior cervical ganglion of adult rat

1978 • 158 citations

A study of cochlear innervation patterns in cats and rats with the Golgi method and Nomarski optics

1975 • 157 citations

The developmental onset of NMDA receptor-channel activity during neuronal migration

1993 • 156 citations

Molecular mechanisms of drug-induced hearing loss

1986 • 155 citations

Age-related changes in the C57BL/6J mouse cochlea. II. Ultrastructural findings

1981 • 155 citations

Activity-dependent plasticity in the visual systems of frogs and fish

1991 • 153 citations

Physiology of the Ear

1988 • 153 citations

Neurobiology of hearing: The cochlea

1987 • 151 citations

A novel cholinergic receptor mediates inhibition of chick cochlear hair cells

1992 • 147 citations

Auditory selective attention in the human cochlea

1994 • 146 citations

Different patterns of cochlear innervation during the development of the kitten

1978 • 145 citations

Endogenous opioids regulate dendritic growth and spine formation in developing rat brain

1987 • 143 citations

Localization of cholinergic and purinergic receptors on outer hair cells isolated from the guinea-pig cochlea

1992 • 142 citations

ATP-induced current in isolated outer hair cells of guinea pig cochlea

1990 • 138 citations

Evidence for two discrete sources of 2f1−f2 distortion-product otoacoustic emission in rabbit. II: Differential physiological vulnerability

1992 • 135 citations

Cellular mechanism of acetylcholine‐induced response in dissociated outer hair cells of guinea‐pig cochlea.

1993 • 134 citations

Advances in Oto-Rhino-Laryngology

1993 • 123 citations

Muscarinic agonists and ATP increase the intracellular Ca2+ concentration in chick cochlear hair cells.

1990 • 121 citations

In vitro pharmacologic characterization of a cholinergic receptor on outer hair cells

1994 • 120 citations

Action of Cholinergic and Anticholinergic Drugs at the Crossed Olivocochlear Bundle-hair Cell Junction

1974 • 118 citations

Effects of contralateral sound on auditory-nerve responses. II. Dependence on stimulus variables

1989 • 116 citations

Synaptic regeneration and functional recovery after excitotoxic injury in the guinea pig cochlea.

1995 • 115 citations

Auditory nerve fiber activity influenced by contralateral ear sound stimulation

1978 • 115 citations

Mechanics of Hearing

1983 • 113 citations

The behavior of acoustic distortion products in the ear canals of chinchillas with normal or damaged ears

1982 • 109 citations

Neurotrophic effects of NMDA receptor activation on developing cerebellar granule cells

1993 • 106 citations

Adenosine Receptors

1990 • 104 citations

Basal nitric oxide production in regulation of cochlear blood flow

1994 • 103 citations

Glutamate Neurotoxicity in the Cochlea: A Possible Consequence of Ischaemic or Anoxic Conditions Occurring in Ageing

1991 • 103 citations

The Spiral Ganglion and the Innervation of the Human Organ of Corti

1988 • 101 citations

Advances in Audiology

1985 • 100 citations

Glutamate and aspartate mimic the afferent transmitter in the cochlea

1979 • 99 citations

α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid electrophysiological and neurotoxic effects in the guinea-pig cochlea

1991 • 98 citations

Masked cochlear whole-nerve response intensity functions altered by electrical stimulation of the crossed olivocochlear bundle

1988 • 96 citations

The Molecular Basis of Opioid Receptor Function

1988 • 95 citations

Neural Connections of the Outer Haircell System

1979 • 93 citations

Three molecular steps of aminoglycoside ototoxicity demonstrated in outer hair cells

1987 • 93 citations

Electrophysiological evidence for the presence of NMDA receptors in the guinea pig cochlea

1991 • 92 citations

Action of putative neurotransmitters in the guinea pig cochlea

1979 • 91 citations

Differential effect of adenosine on pre- and postsynaptic calcium fluxes

1986 • 90 citations

Development of otoacoustic emissions in gerbil: Evidence for micromechanical changes underlying development of the place code

1991 • 87 citations

Effect of GABA-Administration on murine neuroblastoma cells in culture

1981 • 87 citations

A transient embryonic dopamine receptor inhibits growth cone motility and neurite outgrowth in a subset of avian retina neurons

1987 • 87 citations

Evidence that phosphoinositides mediate motility in cochlear outer hair cells

1987 • 86 citations

The efferent modulation of mammalian inner hair cell afferents

1992 • 86 citations

Acoustic Trauma in the Guinea Pig: II.Electron microscopy including the morphology of cell junctions in the organ of Corti

1965 • 85 citations

Effect of Sound Stimulation at Several Levels on Concentrations of Primary Amines, Including Neurotransmitter Candidates, in Perilymph of the Guinea Pig Inner Ear

1983 • 84 citations

Acetylcholine increases intracellular Ca2+ concentration and hyperpolarizes the guinea-pig outer hair cell

1993 • 83 citations

Presynaptic muscarine receptors modulating acetylcholine release

1984 • 82 citations

Immunocytochemical localization of glutamate immunoreactivity in the guinea pig cochlea

1989 • 82 citations

The nature and progression of injury in the organ of Corti during ischemia

1989 • 81 citations

Kainic acid: An evaluation of its action on cockle ar potentials

1981 • 81 citations

Effects of Adenosine 5′-triphosphate and related agonists on cochlear function

1994 • 81 citations

Muscarinic receptor hyperpolarizes cochlear hair cells of chick by activating Ca(2+)‐activated K+ channels.

1991 • 79 citations

Stimulation of Inositol Phospholipid Hydrolysis by Excitatory Amino Acids Is Enhanced in Brain Slices from Vulnerable Regions after Transient Global Ischemia

1989 • 77 citations

Characterization of Ca2+ signals generated by extracellular nucleotides in supporting cells of the organ of Corti

1993 • 76 citations

The effects of kainic acid on the cochlear ganglion of the rat

1989 • 76 citations

Co-expression of NMDA and AMPA/kainate receptor mRNAs in cochlear neurones

1992 • 75 citations

The olivocochlear efferent bundle and susceptibility of the inner ear to acoustic injury

1991 • 74 citations

Nitric oxide synthase is an active enzyme in the spiral ganglion cells of the rat cochlea

1994 • 73 citations

A nicotinic-like receptor mediates suppression of distortion product otoacoustic emissions by contralateral sound

1994 • 73 citations

Pharmacology of hearing: Experimental and clinical bases

1981 • 72 citations

Detection and characterization of nitric oxide synthase in the mammalian cochlea

1994 • 70 citations

Contralateral sound suppresses distortion product otoacoustic emissions through cholinergic mechanisms

1993 • 70 citations

Variability of the influence of a visual task on the active micromechanical properties of the cochlea

1990 • 69 citations

Perinatal Hypoxic‐Ischemic Brain Injury Enhances Quisqualic Acid‐Stimulated Phosphoinositide Turnover

1988 • 69 citations

The acetylcholine receptor molecule: allosteric sites and the ion channel

1987 • 68 citations

Dopaminergic lateral efferent innervation of the guinea-pig cochlea: Immunoelectron microscopy of catecholamine-synthesizing enzymes and effect of 6-hydroxydopamine

1993 • 68 citations

Physiology of Hearing

1971 • 66 citations

Extracellular ATP elevates cytosolic Ca2+ in cochlear inner hair cells

1991 • 65 citations

Active movements of the cuticular plate induce sensory hair motion in mammalian outer hair cells

1988 • 64 citations

Mechanical properties of hair cells

1986 • 63 citations

Effect of adenosine, adenosine triphosphate, adenosine deaminase, dipyridamole and aminophylline on acetylcholine release from electrically-stimulated brain slices

1983 • 62 citations

Excitotoxic Amino Acids

1986 • 61 citations

Physiological roles of adenosine derivatives which are released during neurotransmission in mammalian brain.

1978 • 60 citations

S 14297, a novel selective ligand at cloned human dopamine D3 receptors, blocks 7-OH-DPAT-induced hypothermia in rats

1994 • 58 citations

Correlation Between the Length of Outer Hair Cells and the Frequency Coding of the Cochlea

1992 • 57 citations

Rapid, reversible elimination of medial olivocochlear efferent function following single injections of gentamicin in the guinea pig

1994 • 56 citations

Visual attention and evoked otoacoustic emissions: A slight but real effect

1992 • 56 citations

The quinoxalinediones DNQX, CNQX and two related congeners suppress hair cell-to-auditory nerve transmission

1989 • 55 citations

Tinnitus: some thoughts about its origin

1984 • 53 citations

Glutamate neurotoxicity in the developing rat cochlea: physiological and morphological approaches

1991 • 53 citations

Intracochlear application of acetylcholine alters sound-induced mechanical events within the cochlear partition

1992 • 53 citations

Comparative actions of quisqualate and N-methyl-d-aspartate, excitation amino acid agonists, on guinea-pig cochlear potentials

1986 • 52 citations

Implication of non-NMDA and NMDA receptors in cochlear ischemia

1992 • 51 citations

Kynurenic acid and γ-D-glutamylaminomethylsulfonic acid suppress the compound action potential of the auditory nerve

1987 • 50 citations

Expression of NMDA-receptor mRNA in the rat cochlea

1993 • 48 citations

HPLC detection of dopamine and noradrenaline in the cochlea of adult and developing rats

1989 • 48 citations

Significance of presynaptic formations in early stages of cochlear synaptogenesis

1979 • 47 citations

Elevation of auditory thresholds by spontaneous cochlear oscillations

1995 • 47 citations

ATP antagonists cibacron blue, basilen blue and suramin alter sound-evoked responses of the cochlea and auditory nerve

1994 • 47 citations

Noise Induced Hearing Loss

1990 • 46 citations

The active process is affected first by intense sound exposure

1988 • 45 citations

A M3 muscarinic receptor coupled to inositol phosphate formation in the rat cochlea?

1990 • 44 citations

Occurrence and distribution of non-NMDA glutamate receptor mRNAs in the cochlea

1991 • 44 citations

Release of norepinephrine and dopamine from brain vesicular preparations: Effects of adenosine analogues

1982 • 43 citations

A microiontophoretic study of the role of excitatory amino acids at the afferent synapses of mammalian inner hair cells

1990 • 42 citations

Stimulation of Efferent Olivocochlear Bundle causes Release from Low Level Masking

1970 • 42 citations

Opioid receptors inhibit the adenylate cyclase in guinea pig cochleas

1987 • 41 citations

Preferential glutamine uptake by cochlear hair cells: implications for the afferent cochlear transmitter

1984 • 41 citations

Neurotoxicity of kainic acid in the rat cochlea during early developmental stages

1990 • 40 citations

An ipsilateral cochlear efferent loop protects the cochlea during intense sound exposure

1988 • 40 citations

Kainate and NMDA toxicity for cultured developing and adult rat spiral ganglion neurons: further evidence for a glutamatergic excitatory neurotransmission at the inner hair cell synapse

1991 • 39 citations

Influence of atp and atp agonists on the physiology of the isolated semicircular canal of the frog (Rana Pipiens)

1994 • 39 citations

Pharmacological alterations of the activity of afferent fibers innervating hair cells

1989 • 39 citations

Synaptic connections and putative functions of the dopaminergic innervation of the guinea pig cochlea

1995 • 38 citations

ATP-induced cytoplasmic [Ca2+]increases in isolated cochlear outer hair cells. Involved receptor and channel mechanisms

1994 • 38 citations

γ-aminobutyric acid enables synaptogenesis in the intact superior cervical ganglion of the adult rat

1985 • 38 citations

Lack of effect of DL-α-aminoadipate, an excitatory amino acid antagonist, on cat auditory nerve responses to sound

1980 • 37 citations

Effects of opioid be drugs on auditory evoked potentials suggest a role of lateral olivocochlear dynorphins in auditory function

1991 • 36 citations

The role of outer hair cells in cochlear function.

1985 • 35 citations

Cholinergic regulation of the phosphoinositide second messenger system in the guinea pig organ of Corti

1992 • 35 citations

Quisqualate excites spiral ganglion neurons of the guinea pig

1985 • 34 citations

Appearance of NMDA receptors triggered by anoxia independent of voltage in vivo and in vitro

1991 • 32 citations

Postnatal maturation of spiral ganglion neurons: A horseradish peroxidase study

1991 • 32 citations

Acetylcholine modulated potassium channel in the hair cell of the toadfish saccule

1988 • 32 citations

Effects of noise stimulation on cochlear dopamine metabolism

1993 • 31 citations

Motility in auditory sensory cells

1987 • 30 citations

Effect of kainic acid upon N1 latency

1984 • 30 citations

Effect of noise level on the Met-enkephalin content of the guinea pig cochlea

1987 • 29 citations

Mechanical and neural interactions between binaurally applied sounds in cat cochlear nerve fibers

1980 • 29 citations

Carbachol-induced inositol phosphate formation during rat cochlea development

1990 • 29 citations

Tinnitus associated spontaneous otoacoustic emissions:Active Outer Hair Cell Movements as Common Origin?

1990 • 28 citations

Nicotinic acetylcholine receptor subunits expressed in rat cochlea detected by the polymerase chain reaction

1994 • 26 citations

Effect of Neuroregulators on the Intracellular Calcium Level in the Outer Hair Cell Isolated from the Guinea Pig

1991 • 26 citations

Kainate-induced status epilepticus leads to a delayed increases in various specific glutamate metabotropic receptor responses in the hippocampus

1994 • 24 citations

Adenosine is a modulator of hair cell-afferent neurotransmission

1987 • 23 citations

Localisation of functional muscarinic receptors in the rat cochlea: evidence for efferent presynaptic autoreceptors

1993 • 23 citations

Muscarinic Receptors in the Cochlear Nucleus and Auditory Nerve of the Guinea Pig

1984 • 23 citations

Pharmacology of hearing

1982 • 23 citations

Effect of spider venom on cochlear nerve activity consistent with glutamatergic transmission at hair cell-afferent dendrite synapse

1988 • 22 citations

Neomycin: Ototoxicity And The Cochlear Efferents

1973 • 20 citations

Suppression of auditory nerve activity in the guinea pig cochlea by1-(p-bromobenzoyl)-piperazine-2,3-dicar☐ylic acid

1989 • 20 citations

N-Methyl-d-aspartate-induced oscillations in excitatory afferent neurotransmission in the guinea pig cochlea

1991 • 18 citations

Muscarinic acetylcholine receptor binding in the guinea pig cochlea

1983 • 17 citations

Vascular Pathology in the Human Inner Ear

2015 • 17 citations

Ototoxicity and the olivocochlear bundle

1977 • 17 citations

The phosphoinositide cascade in isolated outer hair cells: possible role as second messenger for motile responses

1986 • 16 citations

Kinetics of piribedil and effects on dopamine metabolism: hepatic biotransformation is not a determinant of its dopaminergic action in rats

1991 • 15 citations

Tinnitus Associated Spontaneous Otoacoustic Emissions: Active Outer Hair Cell Movements as Common Origin?

1990 • 15 citations

Effect of Visual Selective Attention on Otoacoustic Emissions

1989 • 14 citations

Tinnitus and medial cochlear efferent system

1992 • 13 citations

2-Amino-4-phosphonobutyric acid receptors are not involved in synaptic transmission from hair cells to auditory neurons

1988 • 10 citations

Two Control Systems for the Outer Hair Cell Motor

1992 • 9 citations

Blockade of synaptic transmission from hair cells to auditory afferent nerves by 6-Cyano-2,3-dihydroxy-7-nitroquinoxaline, a selective non-NMDA receptor antagonist

1990 • 9 citations

A Comparison of P1‐ and P2‐Purinoceptors

1990 • 9 citations

Neuropeptides in the Sympathetic Innervations of the Cochlea

2015 • 8 citations

The effect of adenosine on cochlear potentials in the guinea pig

1994 • 7 citations

Noise Induced Hearing Loss

1994 • 7 citations

Collegium Oto-Rhino-Laryngologicum Amicitiae Sacrum

2017 • 1 citations

Deleted Work

1955 • 0 citations

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