A M3 muscarinic receptor coupled to inositol phosphate formation in the rat cochlea?

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Evoked Mechanical Responses of Isolated Cochlear Outer Hair Cells

1985 • 1,807 citations

Identification of a Family of Muscarinic Acetylcholine Receptor Genes

1987 • 1,439 citations

Pirenzepine distinguishes between different subclasses of muscarinic receptors

1980 • 1,299 citations

Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor

1986 • 917 citations

Roles of G protein subunits in transmembrane signalling

1988 • 794 citations

Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes

1988 • 792 citations

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

1987 • 766 citations

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

1988 • 669 citations

Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells.

1989 • 627 citations

Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes.

1982 • 573 citations

Primary Structure and Biochemical Properties of an M ₂ Muscarinic Receptor

1987 • 510 citations

Changes in Endolymphatic Potential and Crossed Olivocochlear Bundle Stimulation Alter Cochlear Mechanics

1980 • 443 citations

Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors.

1987 • 442 citations

An M2 Muscarinic Receptor Subtype Coupled to Both Adenylyl Cyclase and Phosphoinositide Turnover

1987 • 398 citations

Efferent neural control of cochlear mechanics? Olivocochlear bundle stimulation affects cochlear biomechanical nonlinearity

1982 • 395 citations

An operational model of pharmacological agonism: the effect of E/[A] curve shape on agonist dissociation constant estimation

1985 • 295 citations

Rapid accumulation of inositol phosphates in isolated rat superior cervical sympathetic ganglia exposed to V1-vasopressin and muscarinic cholinergic stimuli

1984 • 224 citations

Selective coupling with K+ currents of muscarinic acetylcholine receptor subtypes in NG108-15 cells

1988 • 216 citations

Neurotransmission in the inner ear

1986 • 169 citations

Evidence that the phosphatidylinositol cycle is linked to cell motility

1988 • 131 citations

AF-DX 116, a cardioselective muscarinic antagonist.

1987 • 116 citations

Antimuscarinic action of methoctramine, a new cardioselective M-2 muscarinic receptor antagonist, alone and in combination with atropine and gallamine

1987 • 108 citations

Glutamate and aspartate mimic the afferent transmitter in the cochlea

1979 • 99 citations

A new quisqualate receptor subtype (sAA2) responsible for the glutamate-induced inositol phosphate formation in rat brain synaptoneurosomes

1988 • 90 citations

Evidence that phosphoinositides mediate motility in cochlear outer hair cells

1987 • 86 citations

Choline acetyltransferase (ChAT) immunoelectron microscopy distinguishes at least three types of efferent synapses in the organ of Corti

1987 • 84 citations

Muscarinic receptor subtypes insubtypes in Airways

1988 • 72 citations

A radioautographic study of [3H] l-glutamate and [3H] l-glutamine uptake in the guinea-pig cochlea

1983 • 70 citations

Amino acids ? Putative afferent transmitter in the cochlea?

1977 • 68 citations

Pirenzepine indicates heterogeneity of muscarinic receptors linked to cerebral inositol phospholipid metabolism

1985 • 63 citations

The quinoxalinediones DNQX, CNQX and two related congeners suppress hair cell-to-auditory nerve transmission

1989 • 55 citations

Shortening and elongation of isolated outer hak cells in response to application of potassium gluconate, acetylcholine and cationized ferritin

1988 • 54 citations

Comparative actions of quisqualate and N-methyl-d-aspartate, excitation amino acid agonists, on guinea-pig cochlear potentials

1986 • 52 citations

Cochlear neuroactive substances

1989 • 51 citations

A novel subtype of muscarinic receptor identified by homology screening

1987 • 49 citations

The cloned murine M1 muscarinic receptor is associated with the hydrolysis of phosphatidylinositols in transfected murine B82 cells

1988 • 47 citations

Muscarinic receptor heterogeneity in smooth muscle: binding and functional studies with AF-DX 116.

1988 • 47 citations

Control of ionic currents and fluid secretion by muscarinic agonists in exocrine glands

1987 • 43 citations

Electrophysiological characterization of cloned m1 muscarinic receptors expressed in A9 L cells.

1988 • 39 citations

Quisqualate excites spiral ganglion neurons of the guinea pig

1985 • 34 citations

Cholinergic muscarinic receptors in rat cochlea

1988 • 18 citations

The phosphoinositide cascade in isolated outer hair cells: possible role as second messenger for motile responses

1986 • 16 citations

Methoctramine, a cardioselective muscarinic antagonist, stimulates phosphoinositide hydrolysis in rat cerebral cortex

1989 • 5 citations