Alpha 3, alpha 5, and beta 4: three members of the rat neuronal nicotinic acetylcholine receptor-related gene family form a gene cluster.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

Signal sequences

1985 • 2,179 citations

Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat

1989 • 1,049 citations

Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin

1985 • 1,037 citations

Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence

1982 • 730 citations

Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor α-subunit

1986 • 444 citations

Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family.

1987 • 431 citations

Nucleotide and deduced amino acid sequences of Torpedo californica acetylcholine receptor gamma subunit.

1983 • 412 citations

Members of a nicotinic acetylcholine receptor gene family are expressed in different regions of the mammalian central nervous system

1987 • 393 citations

Location of functional regions of acetylcholine receptor α-subunit by site-directed mutagenesis

1985 • 390 citations

Nicotinic receptor of acetylcholine: structure of an oligomeric integral membrane protein

1984 • 373 citations

Acetylcholine receptor binding site contains a disulfide cross-link between adjacent half-cystinyl residues.

1986 • 361 citations

Functional Expression of a New Pharmacological Subtype of Brain Nicotinic Acetylcholine Receptor

1988 • 314 citations

Primary structure and expression of β2: A novel subunit of neuronal nicotinic acetylcholine receptors

1988 • 301 citations

The functional diversity of the neuronal nicotinic acetylcholine receptors is increased by a novel subunit: β4

1989 • 294 citations

Nicotinic binding sites in rat and mouse brain: comparison of acetylcholine, nicotine, and alpha-bungarotoxin.

1986 • 262 citations

Genes expressed in the brain define three distinct neuronal nicotinic acetylcholine receptors.

1988 • 232 citations

β3: A New Member of Nicotinic Acetylcholine Receptor Gene Family Is Expressed in Brain

1989 • 229 citations

alpha-Bungarotoxin binding and cholinergic receptor function on a rat sympathetic nerve line

1977 • 210 citations

Immunological distinction between acetylcholine receptor and the alpha-bungarotoxin-binding component on sympathetic neurons.

1977 • 199 citations

Single-channel currents of rat neuronal nicotinic acetylcholine receptors expressed in xenopus oocytes

1989 • 192 citations

[25] Purification and fractionation of poly(A)+ RNA

1987 • 190 citations

[8] Electrophoresis in agarose and acrylamide gels

1987 • 175 citations

Isolation of a clone coding for the alpha-subunit of a mouse acetylcholine receptor

1985 • 169 citations

Brain and muscle nicotinic acetylcholine receptors are different but homologous proteins.

1985 • 154 citations

Characterization of a putative nicotinic acetylcholine receptor in mammalian brain

1981 • 145 citations

Structure linkage, and sequence of the two genes encoding the delta and gamma subunits of the nicotinic acetylcholine receptor.

1984 • 132 citations

Cloning and sequence analysis of human genomic DNA encoding γ subunit precursor of muscle acetylcholine receptor

1985 • 114 citations

Mapping of brain areas expressing RNA homologous to two different acetylcholine receptor alpha-subunit cDNAs.

1986 • 112 citations

Muscle acetylcholine receptor biosynthesis. Regulation by transcript availability.

1987 • 107 citations

Chromosomal Localization of Muscle Nicotinic Acetylcholine Receptor Genes in the Mouse

1986 • 95 citations

Regulation of acetylcholine receptor transcript expression during development in Xenopus laevis

1988 • 93 citations

How many kinds of nicotinic acetylcholine receptor are there?

1989 • 92 citations

Purification of an acetylcholine receptor from a nonfusing muscle cell line

1977 • 65 citations

Site-directed mutagenesis and single-channel currents define the ionic channel of the nicotinic acetylcholine receptor

1989 • 65 citations

Isolation and sequence of cDNA clones coding for the precursor to the γ subunit of mouse muscle nicotinic acetylcholine receptor

1986 • 59 citations

Differential regulation of acetylcholine sensitivity and alpha- bungarotoxin-binding sites on ciliary ganglion neurons in cell culture

1983 • 51 citations

Characteristics and distribution of high- and low-affinity alpha bungarotoxin binding sites in the rat hypothalamus

1986 • 45 citations

Receptor structure: the accelerating impact of molecular biology

1989 • 38 citations

Cloning of a Putative Neuronal Nicotinic Acetylcholine Receptor Subunit

1989 • 33 citations

Stepwise Activation of the Mouse Acetylcholine Receptor δ- and ϒ-Subunit Genes in Clonal Cell Lines

1988 • 32 citations

Three types of acetylcholine-induced single channel currents in clonal rat pheochromocytoma cells

1983 • 28 citations

Structure-function relationships in nicotinic acetylcholine receptors

1989 • 21 citations