Glucose-induced translocation of protein kinase C in rat pancreatic islets.

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

1967 • 2,783 citations

Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion

1987 • 773 citations

A SENSITIVE, PRECISE RADIOIMMUNOASSAY OF SERUM INSULIN RELYING ON CHARCOAL SEPARATION OF BOUND AND FREE HORMONE MOIETIES

1972 • 634 citations

Isozymic forms of rat brain Ca2+-activated and phospholipid-dependent protein kinase.

1986 • 389 citations

Insulin secretion: Combined effects of phorbol ester and A23187

1983 • 250 citations

Immunochemical evidence that three protein kinase C isozymes increase in abundance during HL-60 differentiation induced by dimethyl sulfoxide and retinoic acid.

1988 • 239 citations

Characterization of the Effects of Arginine and Glucose on Glucagon and Insulin Release from the Perfused Rat Pancreas

1974 • 231 citations

Glucose and carbachol generate 1,2-diacylglycerols by different mechanisms in pancreatic islets.

1988 • 173 citations

Regulation of erythrocyte Ca2+ pump activity by protein kinase C.

1988 • 160 citations

Modulation of dihydropyridine-sensitive Ca2+ channels by glucose metabolism in mouse pancreatic β -cells

1989 • 142 citations

Physiology and Pathophysiology of Insulin Secretion

1990 • 137 citations

Effects of protein kinase C activation on the regulation of the stimulus-secretion coupling in pancreatic β-cells

1989 • 84 citations

Secretagogue-induced diacylglycerol accumulation in isolated pancreatic islets. Mass spectrometric characterization of the fatty acyl content indicates multiple mechanisms of generation

1989 • 83 citations

Comparison of effects of phorbol esters and glucose on protein kinase C activation and insulin secretion in pancreatic islets

1989 • 63 citations

Phosphoinositide Hydrolysis and Insulin Release From Isolated Perifused Rat Islets: Studies With Glucose

1988 • 61 citations

Translocation of protein kinase C in rat islets of Langerhans Effects of a phorbol ester, carbachol and glucose

1989 • 60 citations

Identification and characterization of Ca2+-phospholipid-dependent protein kinase in rat islets and hamster β-cells

1984 • 54 citations

On the Biochemical Nature of Triose- and Hexose- Stimulated Insulin Secretion*

1978 • 49 citations

Perspectives in diabetes. Is protein kinase C required for physiologic insulin release?

1988 • 47 citations

Different Expression of Protein Kinase C Isozymes in Pancreatic Islet Cells*

1990 • 44 citations

Insulin secretion: Combined tolbutamide, forskolin and TPA mimic action of glucose

1984 • 40 citations

Time-dependent potentiation of insulin release induced by alpha-ketoisocaproate and leucine in rats: possible involvement of phosphoinositide hydrolysis

1988 • 28 citations

Insulin Release in RINm5F Cells and Glyceraldehyde Activation of Protein Kinase C

1989 • 15 citations