Perspectives in diabetes. Is protein kinase C required for physiologic insulin release?

Protein kinase C activation by cis-fatty acid in the absence of Ca2+ and phospholipids.

1986 • 309 citations

Insulin secretion: Combined effects of phorbol ester and A23187

1983 • 250 citations

Evidence of protein kinase C involvement in phorbol diester-stimulated arachidonic acid release and prostaglandin synthesis.

1987 • 232 citations

Tumor promoter phorbol myristate acetate inhibits Ca2+ influx through voltage-gated Ca2+ channels in two secretory cell lines, PC12 and RINm5F.

1986 • 178 citations

Insulinotropic effect of the tumor promoter 12-O-tetradecanoylphorbol-13-acetate in rat pancreatic islets.

1980 • 106 citations

Effects of Ca²⁺ and a phorbol ester on insulin secretion from islets of langerhans permeabilised by high‐voltage discharge

1985 • 101 citations

Human polymorphonuclear neutrophil activation with arachidonic acid

1987 • 54 citations

An inhibitory role for polyamines in protein kinase C activation and insulin secretion in mouse pancreatic islets

1986 • 54 citations

Synergistic Effect of a Tumor-Promoting Phorbol Ester and a Hypoglycemic Sulfonylurea upon Insulin Release^*

1983 • 54 citations

Identification and characterization of Ca2+-phospholipid-dependent protein kinase in rat islets and hamster β-cells

1984 • 54 citations

Stimulation of protein kinase C and insulin release by 1-oleoyl-2-acetyl-glycerol

1985 • 52 citations

Distinct functions of down‐regulation‐sensitive and ‐resistant types of protein kinase C in rabbit aortic smooth muscle cells

1987 • 47 citations

Phorbol ester stimulation of insulin release and secretory-granule protein phosphorylation in a transplantable rat insulinoma

1984 • 44 citations

Phorbol esters down-regulate protein kinase C in rat brain cerebral cortical slices

1986 • 30 citations

Protein kinase C negatively modulated by phorbol ester

1986 • 25 citations

Time-dependent changes in protein kinase C distribution and disappearance in phorbol ester-treated human osteosarcoma cells.

1987 • 22 citations

Lipoxygenase Inhibitors Reduce Insulin Secretion Without Impairing Calcium Mobilization*

1987 • 21 citations

In vitro inhibition of rat brain protein kinase C by rhodamine 6G

1987 • 16 citations

Pancreatic islet phospholipase A2: differential, Ca2+-dependent effects of lysophospholipids, arachidonic acid, and its lipoxygenase-derived metabolites on insulin release.

1987 • 10 citations

Specificities of acylglycerols and phospholipids for interaction with phorbol ester receptor on Friend leukemia cells.

1985 • 3 citations