Induction of Long-Term Memory CD8⁺T Cells for Recall of Viral Clearing Responses against Influenza Virus

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

1993 • 2,330 citations

Counting Antigen-Specific CD8 T Cells: A Reevaluation of Bystander Activation during Viral Infection

1998 • 1,996 citations

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1988 • 1,105 citations

Visualizing the generation of memory CD4 T cells in the whole body

2001 • 1,029 citations

In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine

1989 • 632 citations

DISQUISITIONS ON ORIGINAL ANTIGENIC SIN

1966 • 568 citations

A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells

1983 • 561 citations

Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytes.

1985 • 526 citations

Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs

1990 • 479 citations

Protection against lethal Sendai virus infection by in vivo priming of virus-specific cytotoxic T lymphocytes with a free synthetic peptide.

1991 • 334 citations

Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans.

1995 • 332 citations

Influenza nucleoprotein-specific cytotoxic T-cell clones are protective in vivo.

1986 • 261 citations

Peptide-induced antiviral protection by cytotoxic T cells.

1991 • 238 citations

Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide.

1990 • 199 citations

Analysis of cytotoxic T cell responses to dominant and subdominant epitopes during acute and chronic lymphocytic choriomeningitis virus infection.

1996 • 189 citations

Helper-cytotoxic T lymphocyte (CTL) determinant linkage required for priming of anti-HIV CD8+ CTL in vivo with peptide vaccine constructs.

1994 • 181 citations

In vivo induction of cytotoxic T cell response by a free synthetic peptide requires CD4+ T cell help.

1991 • 146 citations

Diminished Primary and Secondary Influenza Virus-Specific CD8⁺T-Cell Responses in CD4-Depleted Ig^−/−Mice

2000 • 142 citations

Enhanced recognition of a modified peptide antigen by cytotoxic T cells specific for influenza nucleoprotein

1988 • 140 citations

The hepatitis B virus-specific CTL responses induced in humans by lipopeptide vaccination are comparable to those elicited by acute viral infection.

1997 • 137 citations

Lipopeptide immunization without adjuvant induces potent and long‐lasting B, T helper, and cytotoxic T lymphocyte responses against a malaria liver stage antigen in mice and chimpanzees

1997 • 124 citations

Relative immunogenicity of the cold-adapted influenza virus A/Ann Arbor/6/60 (A/AA/6/60-ca), recombinants of A/AA/6/60-ca, and parental strains with similar surface antigens

1984 • 107 citations

Extracellular processing of peptide antigens that bind class I major histocompatibility molecules.

1992 • 107 citations

Immunization of mice with lipopeptides bypasses the prerequisite for adjuvant. Immune response of BALB/c mice to human immunodeficiency virus envelope glycoprotein.

1992 • 99 citations

T helper epitopes enhance the cytotoxic response of mice immunized with MHC class I-restricted malaria peptides

1992 • 97 citations

Vaccination of class I major histocompatibility complex (MHC)-restricted murine CD8+ cytotoxic T lymphocytes towards soluble antigens: immunostimulating-ovalbumin complexes enter the class I MHC-restricted antigen pathway and allow sensitization against the immunodominant peptide

1991 • 97 citations

Induction of cytotoxic T lymphocytes in vivo with protein antigen entrapped in membranous vehicles.

1992 • 93 citations

Priming of influenza virus-specific cytotoxic T lymphocytes vivo by short synthetic peptides.

1991 • 88 citations

Protection against lethal viral infection by vaccination with nonimmunodominant peptides.

1996 • 87 citations

Cell-mediated immune responses to influenza virus antigens expressed by vaccinia virus recombinants

1986 • 83 citations

Primary pulmonary cytotoxic T lymphocytes induced by immunization with a vaccinia virus recombinant expressing influenza A virus nucleoprotein peptide do not protect mice against challenge

1994 • 83 citations

The Roles of Influenza Virus Haemagglutinin and Nueleoprotein in Protection: Analysis Using Vaccinia Virus Recombinants

1987 • 82 citations

Induction of protective cytotoxic T cells to murine cytomegalovirus by using a nonapeptide and a human-compatible adjuvant (Montanide ISA 720)

1995 • 66 citations

Endocytosis of an HIV-derived lipopeptide into human dendritic cells followed by class I-restricted CD8+ T lymphocyte activation

2000 • 65 citations

Simian immunodeficiency virus as a model for vaccination against HIV. Induction in rhesus macaques of GAG- or NEF-specific cytotoxic T lymphocytes by lipopeptides.

1994 • 59 citations

Comparative efficiency of simple lipopeptide constructs for in vivo induction of virus-specific CTL

1996 • 56 citations

Mice lacking the transcription factor subunit Rel can clear an influenza infection and have functional anti-viral cytotoxic T cells but do not develop an optimal antibody response

1999 • 55 citations

Long-lasting anti-viral cytotoxic T lymphocytes induced in vivo with chimeric-multirestricted lipopeptides

1995 • 54 citations

Vaccinia virus vectors: new strategies for producing recombinant vaccines

1990 • 53 citations

In vivo primary induction of virus-specific CTL by immunization with 9-mer synthetic peptides

1992 • 53 citations

Lipopeptide particles as the immunologically active component of CTL inducing vaccines

1999 • 52 citations

Efficacy of synthetic vaccines in the induction of cytotoxic T lymphocytes comparison of the costimulating support provided by helper T cells and lipoamino acid

1994 • 51 citations

Priming for in vitro and in vivo anti-human T lymphotropic virus type 1 cellular immunity by virus-related protein reconstituted into liposome.

1991 • 49 citations

Extension of HLA-A*0201-Restricted Minimal Epitope by Nε-Palmitoyl-lysine Increases the Life Span of Functional Presentation to Cytotoxic T Cells

2000 • 47 citations

Novel adjuvants and vaccine delivery systems

1996 • 44 citations

Pools of lipidated HTL-CTL constructs prime for multiple HBV and HCV CTL epitope responses

1998 • 40 citations

Comparison of adjuvant formulations for cytotoxic T cell induction using synthetic peptides

1996 • 32 citations

Influence of strong CD4 epitope on long-term virus-specific cytotoxic T cell responses induced in vivo with peptides

1996 • 32 citations

Localization of the cell activator lipopeptide in bone marrow-derived macrophages by electron energy loss spectroscopy (EELS)

1989 • 30 citations

Conserved Determinants for CD4+ T Cells within the Light Chain of the H3 Hemagglutinin Molecule of Influenza Virus

1994 • 26 citations

Effects of influenza virus-specific cytotoxic T-lymphocyte responses induced by a synthetic nucleoprotein peptide on the survival of mice challenged with a lethal dose of virus

1994 • 15 citations