The many faces of macrophage activation

NITRIC OXIDE AND MACROPHAGE FUNCTION

1997 • 4,106 citations

M-1/M-2 Macrophages and the Th1/Th2 Paradigm

2000 • 2,865 citations

Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation.

1992 • 1,849 citations

Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation

2002 • 1,090 citations

Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation

2002 • 897 citations

Other Functions, Other Genes

1999 • 686 citations

Differential Regulation of Nitric Oxide Synthase-2 and Arginase-1 by Type 1/Type 2 Cytokines In Vivo: Granulomatous Pathology Is Shaped by the Pattern of<scp>l</scp>-Arginine Metabolism

2001 • 674 citations

Reciprocal regulation of the nitric oxide synthase/arginase balance in mouse bone marrow‐derived macrophages by TH 1 and TH 2 cytokines

1995 • 553 citations

Reprogramming of the Macrophage Transcriptome in Response to Interferon-γ and Mycobacterium tuberculosis

2001 • 458 citations

Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages

2002 • 433 citations

Influence of Alternatively and Classically Activated Macrophages on Fibrogenic Activities of Human Fibroblasts

2000 • 432 citations

Selective Suppression of Interleukin-12 Induction after Macrophage Receptor Ligation

1997 • 363 citations

Reversal of Proinflammatory Responses by Ligating the Macrophage Fcγ Receptor Type I

1998 • 330 citations

Alternative versus Classical Activation of Macrophages

1999 • 328 citations

A novel phenotype for an activated macrophage: the type 2 activated macrophage

2002 • 319 citations

Mycobacterium tuberculosis inhibits IFN-gamma transcriptional responses without inhibiting activation of STAT1.

1999 • 318 citations

Cutting Edge: Stat6-Dependent Substrate Depletion Regulates Nitric Oxide Production

2001 • 310 citations

Alternatively Activated Macrophages Differentially Express Fibronectin and Its Splice Variants and the Extracellular Matrix Protein βIG‐H3

2001 • 277 citations

Reversing Lipopolysaccharide Toxicity by Ligating the Macrophage Fcγ Receptors

2001 • 265 citations

Alternative macrophage activation-associated CC-chemokine-1, a novel structural homologue of macrophage inflammatory protein-1 alpha with a Th2-associated expression pattern.

1998 • 253 citations

Mycobacterium tuberculosis Inhibits IFN-γ Transcriptional Responses Without Inhibiting Activation of STAT1

1999 • 248 citations

Alternative Macrophage Activation-Associated CC-Chemokine-1, a Novel Structural Homologue of Macrophage Inflammatory Protein-1α with a Th2-Associated Expression Pattern

1998 • 216 citations

Interferon-lnduced Indoleamine 2,3-Dioxygenase Activity in Human Mononuclear Phagocytes

1989 • 187 citations

Cutting Edge: Biasing Immune Responses by Directing Antigen to Macrophage Fcγ Receptors

2002 • 182 citations

TGF-β in infections and infectious diseases

1999 • 125 citations

Alternatively activated macrophages actively inhibit proliferation of peripheral blood lymphocytes and CD4⁺ T cells in vitro

1997 • 123 citations

Interleukin-10 and its receptor.

1994 • 102 citations

Interleukin-3 and its receptor

1995 • 94 citations

Genetic susceptibility to intracellular infections: Nramp1, macrophage function and divalent cations transport

2000 • 87 citations

Infection and Nitric Oxide

2002 • 71 citations

Activation of the Stem Cell-Derived Tyrosine Kinase/RON Receptor Tyrosine Kinase by Macrophage-Stimulating Protein Results in the Induction of Arginase Activity in Murine Peritoneal Macrophages

2002 • 70 citations

Mechanisms and modulation of macrophage activation.

1991 • 63 citations

Alterations of Surface Properties by Macrophage Activation: Expression of Receptors for Fc and Mannose-Terminal Glycoproteins and Differentiation Antigens

1984 • 61 citations

Association of lung carcinoma and tuberculosis.

1991 • 59 citations

Treatment of murine macrophages with interferon-γ inhibits their ability to bind leishmania promastigotes

1992 • 49 citations

Exploitation of host cell signaling machinery: activation of macrophage phosphotyrosine phosphatases as a novel mechanism of molecular microbial pathogenesis

2000 • 47 citations

The Relationship of Inflammation and Initiation of Autoimmune Disease: Role of TNF Super Family Members

2002 • 34 citations