A novel phenotype for an activated macrophage: the type 2 activated macrophage

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Toll-like receptors: critical proteins linking innate and acquired immunity

2001 • 4,673 citations

Functional diversity of helper T lymphocytes

1996 • 4,512 citations

Interleukin-10-deficient mice develop chronic enterocolitis

1993 • 4,225 citations

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

1991 • 3,812 citations

Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function

1998 • 2,047 citations

Induction by Antigen of Intrathymic Apoptosis of CD4 ⁺ CD8 ⁺ TCR ^lo Thymocytes in Vivo

1990 • 1,781 citations

Cytokines Induce the Development of Functionally Heterogeneous T Helper Cell Subsets

1998 • 1,569 citations

MyD88 Is an Adaptor Protein in the hToll/IL-1 Receptor Family Signaling Pathways

1998 • 1,565 citations

Toll-like receptors control activation of adaptive immune responses

2001 • 1,374 citations

Macrophage deactivation by interleukin 10.

1991 • 1,253 citations

Fc Receptors

1991 • 1,220 citations

IRAK (Pelle) Family Member IRAK-2 and MyD88 as Proximal Mediators of IL-1 Signaling

1997 • 1,159 citations

Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming.

1993 • 991 citations

FcR γ chain deletion results in pleiotrophic effector cell defects

1994 • 967 citations

Genetic Susceptibility to Leishmania : IL-12 Responsiveness in T _H 1 Cell Development

1996 • 367 citations

Selective Suppression of Interleukin-12 Induction after Macrophage Receptor Ligation

1997 • 363 citations

Reversal of Proinflammatory Responses by Ligating the Macrophage Fcγ Receptor Type I

1998 • 330 citations

Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function

1991 • 286 citations

The Role of Macrophages in T Cell–mediated Autoimmune Diabetes in Nonobese Diabetic Mice

1999 • 279 citations

Reversing Lipopolysaccharide Toxicity by Ligating the Macrophage Fcγ Receptors

2001 • 265 citations

Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling.

1999 • 249 citations

Differences Between IL-4- and IL-4 Receptor α-Deficient Mice in Chronic Leishmaniasis Reveal a Protective Role for IL-13 Receptor Signaling

1999 • 204 citations

Cutting Edge: Biasing Immune Responses by Directing Antigen to Macrophage Fcγ Receptors

2002 • 182 citations

Innate Immune Induction of the Adaptive Immune Response

1999 • 145 citations

Endogenous presentation of self myelin epitopes by CNS-resident APCs in Theiler’s virus–infected mice

1999 • 134 citations

Suppression of IL-12 Transcription in Macrophages Following Fcγ Receptor Ligation

2001 • 101 citations

The phoP locus influences processing and presentation of Salmonella typhimurium antigens by activated macrophages

1995 • 91 citations

The role of macrophages in the induction and regulation of immunity elicited by exogenous antigens

1998 • 55 citations