Post-translational Modification of Rta of Epstein-Barr Virus by SUMO-1

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Protein Modification by SUMO

2004 • 1,628 citations

SUMO-1 Modification of IκBα Inhibits NF-κB Activation

1998 • 1,002 citations

Functional Heterogeneity of Small Ubiquitin-related Protein Modifiers SUMO-1 versus SUMO-2/3

2000 • 848 citations

The Nucleoporin RanBP2 Has SUMO1 E3 Ligase Activity

2002 • 787 citations

SUMO—Nonclassical Ubiquitin

2000 • 764 citations

SUMO-1 Conjugation in Vivo Requires Both a Consensus Modification Motif and Nuclear Targeting

2001 • 722 citations

Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

1998 • 676 citations

An E3-like Factor that Promotes SUMO Conjugation to the Yeast Septins

2001 • 642 citations

The Polycomb Protein Pc2 Is a SUMO E3

2003 • 558 citations

Role of SUMO-1–modified PML in nuclear body formation

2000 • 555 citations

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1

1999 • 507 citations

The Small Ubiquitin-like Modifier-1 (SUMO-1) Consensus Sequence Mediates Ubc9 Binding and Is Essential for SUMO-1 Modification

2001 • 506 citations

Ubc9p Is the Conjugating Enzyme for the Ubiquitin-like Protein Smt3p

1997 • 488 citations

Involvement of PIAS1 in the Sumoylation of Tumor Suppressor p53

2001 • 447 citations

Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity

2002 • 441 citations

Modification with SUMO

2003 • 429 citations

PIAS Proteins Modulate Transcription Factors by Functioning as SUMO-1 Ligases

2002 • 420 citations

Induction of the Epstein-Barr virus (EBV) cycle in latently infected cells by n-butyrate

1979 • 385 citations

The Epstein-Barr virus lytic program is controlled by the co-operative functions of two transactivators

2000 • 376 citations

SUMO-1 Modification Represses Sp3 Transcriptional Activation and Modulates Its Subnuclear Localization

2002 • 365 citations

Sequestration and Inhibition of Daxx-Mediated Transcriptional Repression by PML

2000 • 357 citations

Identification of the Enzyme Required for Activation of the Small Ubiquitin-like Protein SUMO-1

1999 • 353 citations

Ubch9 conjugates SUMO but not ubiquitin

1997 • 349 citations

Synchronous and sequential activation of latently infected Epstein-Barr virus genomes

1989 • 333 citations

Evidence for Covalent Modification of the Nuclear Dot–associated Proteins PML and Sp100 by PIC1/SUMO-1

1997 • 329 citations

Viral Immediate-Early Proteins Abrogate the Modification by SUMO-1 of PML and Sp100 Proteins, Correlating with Nuclear Body Disruption

1999 • 303 citations

Enzymes of the SUMO Modification Pathway Localize to Filaments of the Nuclear Pore Complex

2002 • 279 citations

SP-RING for SUMO

2001 • 279 citations

Transcription factor Sp3 is silenced through SUMO modification by PIAS1

2002 • 261 citations

Regulation of Heat Shock Transcription Factor 1 by Stress-induced SUMO-1 Modification

2001 • 256 citations

A new RING for SUMO: wrestling transcriptional responses into nuclear bodies with PIAS family E3 SUMO ligases

2001 • 242 citations

Promyelocytic Leukemia Protein (Pml) and Daxx Participate in a Novel Nuclear Pathway for Apoptosis

2000 • 239 citations

Epstein-Barr Virus Immediate-Early Protein BZLF1 Is SUMO-1 Modified and Disrupts Promyelocytic Leukemia Bodies

2001 • 225 citations

In VitroSUMO-1 Modification Requires Two Enzymatic Steps, E1 and E2

1999 • 224 citations

Post-translational modification by the small ubiquitin-related modifier SUMO has big effects on transcription factor activity

2003 • 220 citations

The Epstein-Barr Virus Rta Protein Activates Lytic Cycle Genes and Can Disrupt Latency in B Lymphocytes

1998 • 216 citations

The ubiquitin-like proteins SMT3 and SUMO-1 are conjugated by the UBC9 E2 enzyme

1998 • 210 citations

Preferential Interaction of Sentrin with a Ubiquitin-conjugating Enzyme, Ubc9

1997 • 190 citations

SUMO-1 Modification Regulates the DNA Binding Activity of Heat Shock Transcription Factor 2, a Promyelocytic Leukemia Nuclear Body Associated Transcription Factor

2001 • 177 citations

Sumoylation of Smad4, the Common Smad Mediator of Transforming Growth Factor-β Family Signaling

2003 • 173 citations

Sumoylation is involved in beta-catenin-dependent activation of Tcf-4

2003 • 167 citations

Covalent Modification of the Transactivator Protein IE2-p86 of Human Cytomegalovirus by Conjugation to the Ubiquitin-Homologous Proteins SUMO-1 and hSMT3b

2000 • 167 citations

Modification of Ran GTPase-activating Protein by the Small Ubiquitin-related Modifier SUMO-1 Requires Ubc9, an E2-type Ubiquitin-conjugating Enzyme Homologue

1998 • 155 citations

Molecular features of human ubiquitin-like SUMO genes and their encoded proteins

2002 • 153 citations

Epstein-Barr virus gene expression in P3HR1-superinfected Raji cells

1987 • 142 citations

Protein modification by SUMO

2001 • 137 citations

Characterization of a Second Member of the Sentrin Family of Ubiquitin-like Proteins

1998 • 131 citations

Evaluation of Interactions of Human Cytomegalovirus Immediate-Early IE2 Regulatory Protein with Small Ubiquitin-Like Modifiers and Their Conjugation Enzyme Ubc9

2001 • 101 citations

Autostimulation of the Epstein-Barr Virus BRLF1 Promoter Is Mediated through Consensus Sp1 and Sp3 Binding Sites

2001 • 92 citations

Activation of the BRLF1 promoter and lytic cycle of Epstein-Barr virus by histone acetylation

2000 • 90 citations

Epstein-Barr Virus Nuclear Antigen 3C Putative Repression Domain Mediates Coactivation of the LMP1 Promoter with EBNA-2

2002 • 90 citations

Proteasome-Independent Disruption of PML Oncogenic Domains (PODs), but Not Covalent Modification by SUMO-1, Is Required for Human Cytomegalovirus Immediate-Early Protein IE1 To Inhibit PML-Mediated Transcriptional Repression

2001 • 83 citations

Efficient transcription of the Epstein-Barr virus immediate-early BZLF1 and BRLF1 genes requires protein synthesis

1991 • 82 citations

Induction of Epstein-Barr virus lytic cycle by tumor-promoting and non-tumor-promoting phorbol esters requires active protein kinase C

1991 • 65 citations

Bovine Papillomavirus E1 Protein Is Sumoylated by the Host Cell Ubc9 Protein

2000 • 64 citations

SUMO-1 Modification of Human Cytomegalovirus IE1/IE72

2002 • 61 citations

EBNA3C Coactivation with EBNA2 Requires a SUMO Homology Domain

2003 • 57 citations

Cloning and Expression of Human Homolog HSMT3 to Yeast SMT3 Suppressor of MIF2 Mutations in a Centromere Protein Gene

1996 • 53 citations

The Epstein-Barr Virus Immediate-Early Gene Product, BRLF1, Interacts with the Retinoblastoma Protein during the Viral Lytic Cycle

1998 • 50 citations

Role of Rta in the Translation of Bicistronic BZLF1 of Epstein-Barr Virus

1998 • 37 citations