Involvement of PIAS1 in the Sumoylation of Tumor Suppressor p53

THE UBIQUITIN SYSTEM

1998 • 8,360 citations

p53, the Cellular Gatekeeper for Growth and Division

1997 • 7,621 citations

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

1997 • 2,510 citations

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

1997 • 1,906 citations

DNA damage activates p53 through a phosphorylation–acetylation cascade

1998 • 1,194 citations

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

1999 • 1,134 citations

The Tyrosine Kinase Negative Regulator c-Cbl as a RING-Type, E2-Dependent Ubiquitin-Protein Ligase

1999 • 1,045 citations

SUMO-1 Modification of IκBα Inhibits NF-κB Activation

1998 • 1,002 citations

Specific Inhibition of Stat3 Signal Transduction by PIAS3

1997 • 971 citations

p53 Sites Acetylated In Vitro by PCAF and p300 Are Acetylated In Vivo in Response to DNA Damage

1999 • 764 citations

Inhibition of Stat1-mediated gene activation by PIAS1

1998 • 760 citations

Sumo, ubiquitin's mysterious cousin

2001 • 749 citations

Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

1998 • 676 citations

SUMO-1 modification activates the transcriptional response of p53

1999 • 627 citations

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1

1999 • 507 citations

Arginine Methylation of STAT1 Modulates IFNα/β-Induced Transcription

2001 • 475 citations

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

2000 • 378 citations

Modulation of STAT signaling by STAT-interacting proteins

2000 • 372 citations

Identification of the Enzyme Required for Activation of the Small Ubiquitin-like Protein SUMO-1

1999 • 353 citations

Evidence for Covalent Modification of the Nuclear Dot–associated Proteins PML and Sp100 by PIC1/SUMO-1

1997 • 329 citations

Ligand-induced Ubiquitination of the Epidermal Growth Factor Receptor Involves the Interaction of the c-Cbl RING Finger and UbcH7

1999 • 328 citations

SUMO-1 modification of the acute promyelocytic leukaemia protein PML: implications for nuclear localisation

1999 • 305 citations

In VitroSUMO-1 Modification Requires Two Enzymatic Steps, E1 and E2

1999 • 224 citations

A transcriptional corepressor of Stat1 with an essential LXXLL signature motif

2001 • 198 citations

RanBP2 associates with Ubc9p and a modified form of RanGAP1

1997 • 190 citations

Molecular cloning and characterization of human AOS1 and UBA2, components of the sentrin‐activating enzyme complex

1999 • 172 citations

ARIP3 (Androgen Receptor-Interacting Protein 3) and Other PIAS (Protein Inhibitor of Activated STAT) Proteins Differ in Their Ability to Modulate Steroid Receptor-Dependent Transcriptional Activation

2000 • 171 citations

Modification of Ran GTPase-activating Protein by the Small Ubiquitin-related Modifier SUMO-1 Requires Ubc9, an E2-type Ubiquitin-conjugating Enzyme Homologue

1998 • 155 citations

The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3

2000 • 133 citations

Distinct roles of the NH ₂ - and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1–Stat1 interaction

2000 • 119 citations

MBP1: a novel mutant p53-specific protein partner with oncogenic properties

1999 • 59 citations