The BCL2 major breakpoint region is a sequence- and cell-cycle-specific binding site of the Ku antigen.

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

Involvement of the bcl -2 Gene in Human Follicular Lymphoma

1985 • 1,797 citations

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

1991 • 1,301 citations

bcl-2-Immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

1989 • 1,252 citations

The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen

1993 • 1,219 citations

The t(14;18) Chromosome Translocations Involved in B-Cell Neoplasms Result from Mistakes in VDJ Joining

1985 • 1,021 citations

Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester.

1979 • 1,019 citations

Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

1985 • 972 citations

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation

1995 • 862 citations

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1994 • 637 citations

Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma.

1988 • 499 citations

Mechanism of interaction between Ku protein and DNA.

1986 • 485 citations

Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositis-scleroderma overlap.

1981 • 430 citations

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen.

1990 • 415 citations

Restoration of X-ray Resistance and V(D)J Recombination in Mutant Cells by Ku cDNA

1994 • 351 citations

A rapid single step staining technique for DNA analysis by flow microfluorimetry.

1980 • 294 citations

bcl-2 proto-oncogene expression in normal and neoplastic human myeloid cells

1992 • 276 citations

Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen.

1994 • 225 citations

Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks.

1994 • 215 citations

Use of monoclonal antibodies for the characterization of novel DNA-binding proteins recognized by human autoimmune sera.

1985 • 156 citations

Human Cells Contain a DNA-Activated Protein Kinase that Phosphorylates Simian Virus 40 T Antigen, Mouse p53, and the Human Ku Autoantigen

1990 • 144 citations

Complementation of the ionizing radiation sensitivity, DNA end binding, and V(D)J recombination defects of double-strand break repair mutants by the p86 Ku autoantigen.

1995 • 138 citations

DNA binding provides a signal for phosphorylation of the RNA polymerase II heptapeptide repeats.

1992 • 133 citations

BCL2 oncogene translocation is mediated by a chi-like consensus.

1992 • 114 citations

The human minisatellite consensus at breakpoints of oncogene translocations

1990 • 111 citations

Phosphorylation of the p34 subunit of human single-stranded-DNA-binding protein in cyclin A-activated G1 extracts is catalyzed by cdk-cyclin A complex and DNA-dependent protein kinase.

1994 • 110 citations

Chi hotspots of generalized recombination

1983 • 106 citations

Purification of an 86-70 kDa nuclear DNA-associated protein complex

1985 • 80 citations

Phosphorylation sites in the amino-terminal region of mouse p53.

1992 • 74 citations

A DNA-binding activity, TRAC, specific for the TRA element of the transferrin receptor gene copurifies with the Ku autoantigen.

1994 • 46 citations

Assembly and DNA binding of recombinant Ku (p70/p80) autoantigen defined by a novel monoclonal antibody specific for p70/p80 heterodimers

1994 • 46 citations

Similar DNA binding properties of free p70 (Ku) subunit and p70/p80 heterodimer

1994 • 27 citations