Cloning and structural characterization of the human endothelial nitric‐oxide‐synthase gene

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

1993 • 7,941 citations

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

1987 • 5,027 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Hypervariable ‘minisatellite’ regions in human DNA

1985 • 3,789 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 2,371 citations

Endothelium‐derived relaxing and contracting factors

1989 • 2,017 citations

Regulatory Functions of the Vascular Endothelium

1990 • 1,899 citations

Molecular basis of human hypertension: Role of angiotensinogen

1992 • 1,861 citations

A second-generation linkage map of the human genome

1992 • 1,721 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

Purification and Biochemical Characterization of the Promoter-Specific Transcription Factor, Sp1

1986 • 1,473 citations

SPLICING OF MESSENGER RNA PRECURSORS

1986 • 1,233 citations

Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

1983 • 1,028 citations

Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide

1990 • 996 citations

Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells.

1991 • 982 citations

Compilation of vertebrate-encoded transcription factors

1992 • 934 citations

Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene

1993 • 881 citations

Splicing of Messenger RNA Precursors

1984 • 874 citations

Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase.

1992 • 748 citations

Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses.

1988 • 736 citations

Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element.

1993 • 638 citations

Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase.

1992 • 616 citations

The highly polymorphic region near the human insulin gene is composed of simple tandemly repeating sequences

1982 • 524 citations

Trinucleotide repeat amplification and hypermethylation of a CpG island in FRAXE mental retardation

1993 • 522 citations

An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes.

1988 • 518 citations

H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes.

1992 • 480 citations

Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase.

1992 • 477 citations

The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites.

1990 • 450 citations

The c-Ets oncoprotein activates the stromelysin promoter through the same elements as several non-nuclear oncoproteins.

1991 • 380 citations

Phosphorylation and subcellular translocation of endothelial nitric oxide synthase.

1993 • 329 citations

The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene

1982 • 323 citations

Estrogen-induced uterine vasodilatation is antagonized by L-nitroarginine methyl ester, an inhibitor of nitric oxide synthesis

1992 • 312 citations

H-2RIIBP, a member of the nuclear hormone receptor superfamily that binds to both the regulatory element of major histocompatibility class I genes and the estrogen response element.

1989 • 306 citations

Endothelial nitric oxide synthase. N-terminal myristoylation determines subcellular localization.

1993 • 275 citations

Purification of nitric oxide synthase from rat macrophages

1991 • 244 citations

Gene Structure, Polymorphism and Mapping of the Human Endothelial Nitric Oxide Synthase Gene

1994 • 230 citations

Calmodulin-independent nitric oxide synthase from rat polymorphonuclear neutrophils

1991 • 195 citations

Activation of the polyomavirus enhancer by a murine activator protein 1 (AP1) homolog and two contiguous proteins.

1988 • 186 citations

The CGTCA sequence motif is essential for biological activity of the vasoactive intestinal peptide gene cAMP-regulated enhancer.

1988 • 181 citations

Constitutive and IL-6-induced nuclear factors that interact with the human C-reactive protein promoter.

1990 • 176 citations

Highly variable regions of DNA flank the human α globin genes

1981 • 169 citations

Endothelial nitric oxide synthase is myristylated

1992 • 93 citations

Interferon gamma response region in the promoter of the human DPA gene.

1990 • 86 citations

The heat stable antigen (mouse CD24) gene is differentially regulated but has a housekeeping promoter.

1993 • 49 citations

Positive and negative regulatory elements of chicken vitellogenin II gene characterized by in vitro transcription competition assays in a homologous system.

1990 • 28 citations