Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element.
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References (45)
Molecular cloning: A laboratory manual
1990 • 85,659 citations
Studies and Perspectives of Protein Kinase C
1986 • 5,148 citations
Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.
1989 • 1,660 citations
Regular physical exercise and low-fat diet. Effects on progression of coronary artery disease.
1992 • 1,349 citations
The regulation of transcription by phosphorylation
1992 • 1,316 citations
Cytokines and endothelial cell biology
1990 • 1,275 citations
Flow Effects on Prostacyclin Production by Cultured Human Endothelial Cells
1985 • 1,237 citations
The Dynamic Response of Vascular Endothelial Cells to Fluid Shear Stress
1981 • 1,123 citations
Reductions in Arterial Diameter Produced by Chronic Decreases in Blood Flow Are Endothelium-Dependent
1986 • 1,106 citations
Inhibition of Neointimal Smooth Muscle Accumulation After Angioplasty by an Antibody to PDGF
1991 • 1,081 citations
Mechanical stress mechanisms and the cell. An endothelial paradigm.
1993 • 636 citations
Shear stress regulation of artery lumen diameter in experimental atherogenesis
1987 • 567 citations
Functional analysis of the human vascular cell adhesion molecule 1 promoter.
1992 • 442 citations
Vasoconstriction: A New Activity for Platelet-Derived Growth Factor
1986 • 430 citations
PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model
1991 • 410 citations
Characterization of the Promoter Region of the Human Transforming Growth Factor-β1 Gene
1989 • 400 citations
Influence of hemodynamic forces on vascular endothelial function. In vitro studies of shear stress and pinocytosis in bovine aortic cells.
1984 • 364 citations
Fluid shear stress modulates cytosolic free calcium in vascular endothelial cells
1992 • 355 citations
Adaptations of carotid arteries of young and mature rabbits to reduced carotid blood flow
1989 • 288 citations
Tissue plasminogen activator messenger RNA levels increase in cultured human endothelial cells exposed to laminar shear stress
1990 • 276 citations
An NFxB-like factor is essential but not sufficient for cytokine induction of endothelial leukocyte adhesion molecule 1 (ELAM-1) gene transcription
1991 • 245 citations
Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1.
1992 • 226 citations
Shear stress increases inositol trisphosphate levels in human endothelial cells
1990 • 215 citations
Shear stress increases endothelial platelet-derived growth factor mRNA levels
1991 • 208 citations
Pulsatile and steady flow induces c‐fos expression in human endothelial cells
1993 • 203 citations
Cloning and characterization of the 5'-transcriptional regulatory region of the human intercellular adhesion molecule 1 gene
1991 • 171 citations
Gene Expression During Normal and Malignant Differentiation
1986 • 157 citations
Mechanism of shear-induced prostacyclin production in endothelial cells
1989 • 136 citations
Shear‐induced platelet‐derived growth factor gene expression in human endothelial cells is mediated by protein kinase C
1992 • 134 citations
Orientation of endothelial cells in shear fields in vitro
1984 • 133 citations
Characterization of the mouse transforming growth factor-beta 1 promoter and activation by the Ha-ras oncogene.
1991 • 131 citations
A dictionary of transcription control sequences
1990 • 124 citations
Platelet-derived growth factor and its role in health and disease
1990 • 120 citations
Sequences of the 5′ portion of the humanc-sisgene: characterization of the transcriptional promoter and regulation of expression of the protein product by 5' untranslated mRNA sequences
1987 • 87 citations
Dynamics of shear-induced redistribution of F-actin in endothelial cells in vivo.
1991 • 78 citations
Functional identification of regulatory elements within the promoter region of platelet-derived growth factor 2.
1989 • 67 citations
The structure of the TATA-less rat tissue-type plasminogen activator gene. Species-specific sequence divergences in the promoter predict differences in regulation of gene expression.
1990 • 64 citations
Endothelial cell biology in health and disease
1989 • 57 citations
Role of Blood Flow in Atherogenesis
1988 • 54 citations
Dynamics of shear-induced redistribution of F-actin in endothelial cells in vivo.
1991 • 52 citations
Regulation of Genetic Expression in Shear Stress–stimulated Endothelial Cellsa
1992 • 42 citations
Structure of the murine c-sis proto-oncogene (Sis, PDGFB) encoding the B chain of platelet-derived growth factor
1991 • 40 citations
Endothelial Dysfunction and Atherosclerosis
1989 • 30 citations
Characterization of the Mouse Transforming Growth Factor-β1 Promoter and Activation by the Ha-ras Oncogene
1991 • 23 citations
Functional Identification of Regulatory Elements within the Promoter Region of Platelet-Derived Growth Factor 2
1989 • 10 citations