Endothelial nitric oxide synthase is myristylated

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Vascular endothelial cells synthesize nitric oxide from L-arginine

1988 • 4,800 citations

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

1990 • 3,304 citations

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

1988 • 2,572 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 2,371 citations

Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages

1992 • 1,914 citations

Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.

1989 • 1,850 citations

Role of nitric oxide synthesis in macrophage antimicrobial activity

1991 • 1,547 citations

Macrophage Cytotoxicity: Role for L-Arginine Deiminase and Imino Nitrogen Oxidation to Nitrite

1987 • 1,533 citations

Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.

1989 • 1,443 citations

Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells.

1991 • 982 citations

Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP.

1983 • 949 citations

Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line.

1992 • 877 citations

Isoforms of nitric oxide synthase Characterization and purification from different cell types

1991 • 827 citations

Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein.

1991 • 812 citations

Cyclic guanosine monophosphate as a mediator of vasodilation.

1986 • 811 citations

Macrophage Oxidation of L-Arginine to Nitric Oxide, Nitrite, and Nitrate

1989 • 681 citations

Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells.

1991 • 599 citations

Calcium‐dependent nitric oxide synthesis in endothelial cytosol is mediated by calmodulin

1990 • 507 citations

Purification of the inducible murine macrophage nitric oxide synthase. Identification as a flavoprotein.

1991 • 458 citations

Purification of a Ca²⁺/calmodulin‐dependent nitric oxide synthase from porcine cerebellum

1990 • 433 citations

Arginine is a physiological precursor of endothelium-derived nitric oxide

1988 • 392 citations

Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase.

1991 • 386 citations

Two classes of fatty acid acylated proteins exist in eukaryotic cells.

1985 • 196 citations

Endothelium-derived relaxing factor from cultured human endothelial cells inhibits aggregation of human platelets

1987 • 181 citations

Identification of a 32K plasma membrane protein that binds to the myristylated amino-terminal sequence of p60v-src

1990 • 162 citations

The first seven amino acids encoded by the v-src oncogene act as a myristylation signal: lysine 7 is a critical determinant.

1988 • 136 citations

Purification and characterization of a human NO synthase

1991 • 115 citations

Studies on the attachment of myristic and palmitic acid to cell proteins in human squamous carcinoma cell lines: evidence for two pathways.

1985 • 100 citations

Purification of Insoluble Nitric Oxide Synthase from Rat Cerebellum1

1992 • 73 citations

Induced RAW 264.7 macrophages express soluble and particulate nitric oxide synthase: inhibition by transforming growth factor-ß

1992 • 72 citations

Endothelial cells have a particulate enzyme system responsible for EDRF formation: Measurement by vascular relaxation

1991 • 48 citations

Acylation and prenylation of proteins

1990 • 40 citations

Cytosolic and Membrane-Bound Nitric Oxide Synthase.

1991 • 27 citations

Frequency stability of solar oscillations

1988 • 26 citations