Protective role of the inhibitor of apoptosis protein, survivin, in toxin‐induced acute renal failure

Control of apoptosis and mitotic spindle checkpoint by survivin

1998 • 1,881 citations

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA

1999 • 1,702 citations

IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.

1998 • 1,243 citations

Survivin, versatile modulation of cell division and apoptosis in cancer

2003 • 880 citations

Transcriptional Repression of the Anti-apoptoticsurvivin Gene by Wild Type p53

2002 • 789 citations

Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation

1999 • 562 citations

Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype

2000 • 534 citations

A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy.

2000 • 491 citations

Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury

2001 • 389 citations

Expression and Targeting of the Apoptosis Inhibitor, Survivin, in Human Melanoma

1999 • 371 citations

Cell death induced by acute renal injury: a perspective on the contributions of apoptosis and necrosis

2003 • 361 citations

Epidemiology, management, and outcome of severe acute renal failure of critical illness in Australia

2001 • 352 citations

Survivin promotes cell proliferation in human hepatocellular carcinoma

2000 • 329 citations

Survivin study: What is the next wave?

2003 • 313 citations

Role of apoptosis in the pathogenesis of acute renal failure

2002 • 245 citations

Gene expression in early ischemic renal injury: clues towards pathogenesis, biomarker discovery, and novel therapeutics

2003 • 231 citations

Direct involvement of the receptor-mediated apoptotic pathways in cisplatin-induced renal tubular cell death

2003 • 230 citations

P53 Mediates the Apoptotic Response to GTP Depletion after Renal Ischemia-Reperfusion

2003 • 223 citations

Down-regulation of Survivin by Antisense Oligonucleotides Increases Apoptosis, Inhibits Cytokinesis and Anchorage-Independent Growth

2000 • 205 citations

Regulation of PUMA-α by p53 in cisplatin-induced renal cell apoptosis

2006 • 199 citations

Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53

2001 • 198 citations

Inflammation-associated Cell Cycle–independent Block of Apoptosis by Survivin in Terminally Differentiated Neutrophils

2004 • 196 citations

The pathogenesis of septic acute renal failure

2003 • 193 citations

Survivin study: An update of “What is the next wave?”

2006 • 189 citations

Caspase-1–deficient mice are protected against cisplatin-induced apoptosis and acute tubular necrosis

2004 • 184 citations

Induction of apoptosis in ischemia-reperfusion model of mouse kidney

1998 • 175 citations

A Pathophysiologic Role for T Lymphocytes in Murine Acute Cisplatin Nephrotoxicity

2006 • 174 citations

Three differentially expressed survivin cDNA variants encode proteins with distinct antiapoptotic functions

2000 • 174 citations

Hydroxyl radical scavenger ameliorates cisplatin-induced nephrotoxicity by preventing oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria

2007 • 162 citations

Cytokine cooperation in renal tubular cell injury: The role of TWEAK

2006 • 156 citations

Apoptosis of Tubular Epithelial Cells in Donor Kidney Biopsies Predicts Early Renal Allograft Function

1999 • 154 citations

Guanosine supplementation reduces apoptosis and protects renal function in the setting of ischemic injury

2001 • 149 citations

Acute Ablation of Survivin Uncovers p53-dependent Mitotic Checkpoint Functions and Control of Mitochondrial Apoptosis

2004 • 147 citations

Expression of apoptosis regulatory proteins in tubular epithelium stressed in culture or following acute renal failure

2000 • 133 citations

Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF

2005 • 128 citations

Single Injection of Naked Plasmid Encoding Hepatocyte Growth Factor Prevents Cell Death and Ameliorates Acute Renal Failure in Mice

2002 • 124 citations

Minocycline inhibits apoptosis and inflammation in a rat model of ischemic renal injury

2004 • 122 citations

Induction of apoptosis in mesothelioma cells by antisurvivin oligonucleotides.

2002 • 105 citations

Antioxidant ameliorates cisplatin-induced renal tubular cell death through inhibition of death receptor-mediated pathways

2003 • 105 citations

Deficiency of survivin in transgenic mice exacerbates Fas-induced apoptosis via mitochondrial pathways

2002 • 96 citations

Survivin-Dependent Angiogenesis in Ischemic Brain

2003 • 89 citations

Cellular and molecular studies on cisplatin-induced apoptotic cell death in rat kidney

2004 • 84 citations

Long-term therapeutic levels of human alpha-1 antitrypsin in plasma after hydrodynamic injection of nonviral DNA

2003 • 83 citations

Atorvastatin Improves the Course of Ischemic Acute Renal Failure in Aging Rats

2004 • 80 citations

Bid deficiency ameliorates ischemic renal failure and delays animal death in C57BL/6 mice

2005 • 69 citations

Acute toxic renal failure

2004 • 63 citations

Prevention of Acute Ischemic Renal Failure by Targeted Delivery of Growth Factors to the Proximal Tubule in Transgenic Mice

2004 • 59 citations

Lysophosphatidic Acid Prevents Renal Ischemia-Reperfusion Injury by Inhibition of Apoptosis and Complement Activation

2003 • 57 citations

Failure of BCL-2 Up-Regulation in Proximal Tubular Epithelial Cells of Donor Kidney Biopsy Specimens Is Associated with Apoptosis and Delayed Graft Function

2002 • 56 citations

Protein biomarkers associated with acute renal failure and chronic kidney disease

2006 • 56 citations

Lack of the Growth Factor Midkine Enhances Survival against Cisplatin-Induced Renal Damage

2004 • 50 citations

Molecular mechanisms of recovery from acute renal failure

2003 • 47 citations

Expression of Smac/Diablo in tubular epithelial cells and during acute renal failure

2003 • 36 citations

Inhibition of apoptosis by survivin improves transplantation of pancreatic islets for treatment of diabetes in mice

2006 • 31 citations

Apoptotic Cell Death in Renal Injury: The Rationale for Intervention

2002 • 30 citations

Folic acid-induced renal injury and repair. Correlation of structural and functional abnormalities.

1980 • 29 citations

Role of caspases in renal tubular epithelial cell injury

2003 • 21 citations

Mitochondrial Dynamics Of Survivin And “Four Dimensional” Control Of Tumor Cell Apoptosis

2004 • 20 citations

Blocking tumor necrosis factor-α inhibits folic acid-induced acute renal failure

2006 • 17 citations

Par-4 is a novel mediator of renal tubule cell death in models of ischemia-reperfusion injury

2006 • 17 citations