A Second Canon

LDL-receptor-related proteins in Wnt signal transduction

2000 • 1,305 citations

Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation

2000 • 992 citations

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

2002 • 945 citations

Zebrafish Prickle, a Modulator of Noncanonical Wnt/Fz Signaling, Regulates Gastrulation Movements

2003 • 907 citations

arrow encodes an LDL-receptor-related protein essential for Wingless signalling

2000 • 870 citations

The Wnt/Ca2+ pathway

2000 • 843 citations

Wnt/Frizzled Activation of Rho Regulates Vertebrate Gastrulation and Requires a Novel Formin Homology Protein Daam1

2001 • 807 citations

Dishevelled Activates JNK and Discriminates between JNK Pathways in Planar Polarity and wingless Signaling

1998 • 774 citations

The receptor tyrosine kinase Ror2 is involved in non‐canonical Wnt5a/JNK signalling pathway

2003 • 758 citations

Dishevelled controls cell polarity during Xenopus gastrulation

2000 • 750 citations

Shaping the Vertebrate Body Plan by Polarized Embryonic Cell Movements

2002 • 718 citations

Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3–independent β-catenin degradation

2003 • 716 citations

Flamingo, a Seven-Pass Transmembrane Cadherin, Regulates Planar Cell Polarity under the Control of Frizzled

1999 • 703 citations

Mechanism and function of signal transduction by the Wnt/β-catenin and Wnt/Ca2+ pathways

1999 • 699 citations

Axonal Remodeling and Synaptic Differentiation in the Cerebellum Is Regulated by WNT-7a Signaling

2000 • 686 citations

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

2003 • 678 citations

Localization of apical epithelial determinants by the basolateral PDZ protein Scribble

2000 • 678 citations

Xwnt11is a target ofXenopusBrachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway

2000 • 677 citations

Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling

1997 • 671 citations

Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

1998 • 642 citations

The TAK1–NLK–MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF

1999 • 613 citations

Mutation of Celsr1 Disrupts Planar Polarity of Inner Ear Hair Cells and Causes Severe Neural Tube Defects in the Mouse

2003 • 605 citations

Convergent Extension

2002 • 580 citations

Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation

2003 • 580 citations

The role of RhoA in tissue polarity and Frizzled signalling

1997 • 558 citations

Drosophila Rho-Associated Kinase (Drok) Links Frizzled-Mediated Planar Cell Polarity Signaling to the Actin Cytoskeleton

2001 • 546 citations

The TAK1-NLK Mitogen-Activated Protein Kinase Cascade Functions in the Wnt-5a/Ca²⁺ Pathway To Antagonize Wnt/β-Catenin Signaling

2002 • 540 citations

Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis

2002 • 534 citations

The Wnt signalling pathway

2002 • 534 citations

Ca2+/Calmodulin-dependent Protein Kinase II Is Stimulated by Wnt and Frizzled Homologs and Promotes Ventral Cell Fates in Xenopus

2000 • 497 citations

A Member of the Frizzled Protein Family Mediating Axis Induction by Wnt-5A

1997 • 493 citations

Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements

2002 • 491 citations

Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail

2001 • 487 citations

Wnt antagonism initiates cardiogenesis in Xenopus laevis

2001 • 479 citations

Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in aG-protein-dependent manner

1999 • 476 citations

The Zebrafish Glypican Knypek Controls Cell Polarity during Gastrulation Movements of Convergent Extension

2001 • 446 citations

JNK functions in the non‐canonical Wnt pathway to regulate convergent extension movements in vertebrates

2002 • 444 citations

Prickle Mediates Feedback Amplification to Generate Asymmetric Planar Cell Polarity Signaling

2002 • 437 citations

Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling

2001 • 433 citations

Planar Signaling and Morphogenesis in Drosophila

2002 • 428 citations

Wnt-mediated axon guidance via the Drosophila Derailed receptor

2003 • 416 citations

Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development.

1996 • 405 citations

Modulation of Embryonic Intracellular Ca2+Signaling byWnt-5A

1997 • 381 citations

The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos

2001 • 373 citations

Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos

2003 • 337 citations

Zebrafish Rho Kinase 2 Acts Downstream of Wnt11 to Mediate Cell Polarity and Effective Convergence and Extension Movements

2002 • 334 citations

Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?

2002 • 334 citations

A nodal-related gene defines a physical and functional domain within the Spemann organizer

1995 • 332 citations

Xwnt-5A: a maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis

1993 • 330 citations

Asymmetric Localization of Frizzled and the Establishment of Cell Polarity in the Drosophila Wing

2001 • 323 citations

Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis

2000 • 320 citations

The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation

2003 • 319 citations

Strabismus is asymmetrically localised and binds to Prickle and Dishevelled duringDrosophilaplanar polarity patterning

2003 • 315 citations

Identification of Distinct Classes and Functional Domains of Wnts through Expression of Wild-Type and Chimeric Proteins in Xenopus Embryos

1995 • 314 citations

The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos

2002 • 308 citations

Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis

2000 • 291 citations

Dishevelled Proteins Lead to Two Signaling Pathways

1999 • 291 citations

Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/β-catenin activity

2003 • 265 citations

Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish

2003 • 260 citations

Frizzled-7 signalling controls tissue separation during Xenopus gastrulation

2001 • 259 citations

The Ankyrin Repeat Protein Diego Mediates Frizzled-Dependent Planar Polarization

2001 • 241 citations

The planar polarity gene strabismus regulates convergent extension movements in Xenopus

2002 • 233 citations

The Planar Cell Polarity Gene Strabismus Regulates Convergence and Extension and Neural Fold Closure in Xenopus

2002 • 232 citations

Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila.

1996 • 215 citations

WNT-3, Expressed by Motoneurons, Regulates Terminal Arborization of Neurotrophin-3-Responsive Spinal Sensory Neurons

2002 • 204 citations

Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea

2003 • 200 citations

The prickle-Related Gene in Vertebrates Is Essential for Gastrulation Cell Movements

2003 • 193 citations

Jun mediates Frizzled-induced R3/R4 cell fate distinction and planar polarity determination in the Drosophila eye

2000 • 192 citations

Bmp Activity Gradient Regulates Convergent Extension during Zebrafish Gastrulation

2002 • 187 citations

Wnt5 is required for tail formation in the zebrafish embryo.

1997 • 183 citations

Frizzled signaling and the developmental control of cell polarity

1998 • 183 citations

Stat3 Controls Cell Movements during Zebrafish Gastrulation

2002 • 177 citations

WNT11 promotes cardiac tissue formation of early mesoderm

1999 • 176 citations

Xenopus frizzled 7 can act in canonical and non-canonical Wnt signaling pathways: implications on early patterning and morphogenesis

2000 • 175 citations

PKCδ is essential for Dishevelled function in a noncanonical Wnt pathway that regulatesXenopusconvergent extension movements

2003 • 171 citations

Convergence and extension in vertebrate gastrulae: cell movements according to or in search of identity?

2002 • 167 citations

Xenopus Cdc42 Regulates Convergent Extension Movements during Gastrulation through Wnt/Ca2+ Signaling Pathway

2002 • 164 citations

Wnt signalling regulates myogenic differentiation in the developing avian wing

2003 • 161 citations

Frizzled and DFrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development

1999 • 161 citations

Wnt Signaling, Ca ^{2 +} , and Cyclic GMP: Visualizing Frizzled Functions

2003 • 157 citations

Calcium signaling during convergent extension in Xenopus

2001 • 156 citations

Distinct Domains of Mouse Dishevelled Are Responsible for the c-Jun N-terminal Kinase/Stress-activated Protein Kinase Activation and the Axis Formation in Vertebrates

1999 • 148 citations

DWnt4 Regulates Cell Movement and Focal Adhesion Kinase during Drosophila Ovarian Morphogenesis

2002 • 138 citations

Axin Forms a Complex with MEKK1 and Activates c-Jun NH2-terminal Kinase/Stress-activated Protein Kinase through Domains Distinct from Wnt Signaling

1999 • 128 citations

Frizzled signaling and cell–cell interactions in planar polarity

2001 • 118 citations

Monopolar Protrusive Activity: A New Morphogenic Cell Behavior in the Neural Plate Dependent on Vertical Interactions with the Mesoderm in Xenopus

2000 • 106 citations

Antisensewnt-5a Mimicswnt-1-Mediated C57MG Mammary Epithelial Cell Transformation

1998 • 104 citations

Activation of Gβγ signaling downstream of Wnt-11/Xfz7 regulates Cdc42 activity during Xenopus gastrulation

2003 • 84 citations

Wnt‐5a and G‐protein signaling are required for collagen‐induced DDR1 receptor activation and normal mammary cell adhesion

2002 • 80 citations

Endothelial Cells Stimulate T Cell NFAT Nuclear Translocation in the Presence of Cyclosporin A: Involvement of the wnt/Glycogen Synthase Kinase-3β Pathway

2002 • 76 citations

Coupling Planar Cell Polarity Signaling to Morphogenesis

2002 • 64 citations

The role of fibroblast growth factors in early Xenopus development.

1996 • 53 citations

Zebrafish frizzled‐2 morphant displays defects in body axis elongation

2001 • 46 citations

Local activation of protein kinase A inhibits morphogenetic movements during Xenopus gastrulation

2003 • 9 citations