Prickle Mediates Feedback Amplification to Generate Asymmetric Planar Cell Polarity Signaling

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

Analysis of genetic mosaics in developing and adult Drosophila tissues

1993 • 2,029 citations

A new member of the frizzled family from Drosophila functions as a Wingless receptor

1996 • 1,489 citations

Polarization of Chemoattractant Receptor Signaling During Neutrophil Chemotaxis

2000 • 892 citations

Wnt/Frizzled Activation of Rho Regulates Vertebrate Gastrulation and Requires a Novel Formin Homology Protein Daam1

2001 • 807 citations

Flamingo, a Seven-Pass Transmembrane Cadherin, Regulates Planar Cell Polarity under the Control of Frizzled

1999 • 703 citations

Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

1998 • 642 citations

G Protein Signaling Events Are Activated at the Leading Edge of Chemotactic Cells

1998 • 626 citations

Drosophila Rho-Associated Kinase (Drok) Links Frizzled-Mediated Planar Cell Polarity Signaling to the Actin Cytoskeleton

2001 • 546 citations

Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling

2001 • 433 citations

The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal.

1994 • 407 citations

The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos

2001 • 373 citations

Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing

1997 • 369 citations

A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains

1989 • 367 citations

Regulation of Frizzled by Fat-like Cadherins during Planar Polarity Signaling in the Drosophila Compound Eye

2002 • 363 citations

Directional non-cell autonomy and the transmission of polarity information by the frizzled gene of Drosophila

1987 • 351 citations

A genetic analysis of the determination of cuticular polarity during development inDrosophila melanogaster

1982 • 344 citations

dishevelled is required during wingless signaling to establish both cell polarity and cell identity

1994 • 335 citations

Asymmetric Localization of Frizzled and the Establishment of Cell Polarity in the Drosophila Wing

2001 • 323 citations

Van Gogh: A New Drosophila Tissue Polarity Gene

1998 • 317 citations

strabismus, a novel gene that regulates tissue polarity and cell fate decisions in Drosophila

1998 • 310 citations

Tissue polarity genes of Drosophila regulate the subcellular location for prehair initiation in pupal wing cells.

1993 • 301 citations

The balance between isoforms of the Prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discs

1999 • 275 citations

The Drosophila tissue polarity gene starry night encodes a member of the protocadherin family

1999 • 255 citations

Casein kinase 2associates with and phosphorylates Dishevelled

1997 • 249 citations

Frizzled regulation of Notch signalling polarizes cell fate in the Drosophila eye

1999 • 248 citations

The Ankyrin Repeat Protein Diego Mediates Frizzled-Dependent Planar Polarization

2001 • 241 citations

Asymmetric Notch activation specifies photoreceptors R3 and R4 and planar polarity in the Drosophila eye

1999 • 224 citations

Wingless transduction by the Frizzled and Frizzled2 proteins of Drosophila

1999 • 188 citations

Frizzled signaling and the developmental control of cell polarity

1998 • 183 citations

dishevelled is a component of the frizzled signaling pathway in Drosophila

1995 • 176 citations

The genetic control of tissue polarity in Drosophila

1992 • 175 citations

Tissue polarity points from cells that have higher Frizzled levels towards cells that have lower Frizzled levels

1997 • 161 citations

Frizzled and DFrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development

1999 • 161 citations

Planar polarization of Drosophila and vertebrate epithelia

1997 • 125 citations

A Nuclear GFP That Marks Nuclei in Living Drosophila Embryos; Maternal Supply Overcomes a Delay in the Appearance of Zygotic Fluorescence

1995 • 113 citations

frizzled and frizzled 2 Play a Partially Redundant Role in Wingless Signaling and Have Similar Requirements to Wingless in Neurogenesis

1998 • 111 citations

A single frizzled protein has a dual function in tissue polarity

1994 • 108 citations

A Cell-Autonomous, Ubiquitous Marker for the Analysis of Drosophila Genetic Mosaics

1994 • 108 citations

Polarity determination in the Drosophila eye

1999 • 86 citations

Genes controlling cellular polarity in Drosophila

1993 • 75 citations

Genetics of epithelial polarity and pattern in the Drosophila retina

1999 • 65 citations

Coupling Planar Cell Polarity Signaling to Morphogenesis

2002 • 64 citations

The Drosophila tissue polarity gene inturned functions prior to wing hair morphogenesis in the regulation of hair polarity and number.

1994 • 50 citations

The cold-sensitive period for frizzled in the development of wing hair polarity ends prior to the start of hair morphogenesis

1994 • 25 citations

Cellular polarity, mitotic synchrony and axes of symmetry during growth. Where does the information come from?

1998 • 15 citations