Brain-derived neurotrophic factor, nerve growth factor and neurotrophin-3 in selected regions of the rat brain following kainic acid-induced seizure activity

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Calbindin D-28k and parvalbumin in the rat nervous system

1990 • 2,068 citations

Neurotrophins and Neuronal Plasticity

1995 • 1,937 citations

Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy

1985 • 1,730 citations

Trophic factors and neuronal survival

1989 • 1,631 citations

Ca2+ Influx Regulates BDNF Transcription by a CREB Family Transcription Factor-Dependent Mechanism

1998 • 1,504 citations

BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra

1991 • 1,487 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus

1995 • 1,354 citations

NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression

1990 • 1,238 citations

Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family

1990 • 1,140 citations

Distribution of Brain-Derived Neurotrophic Factor (BDNF) Protein and mRNA in the Normal Adult Rat CNS: Evidence for Anterograde Axonal Transport

1997 • 1,093 citations

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

1994 • 1,066 citations

Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors.

1990 • 899 citations

Anterograde transport of brain-derived neurotrophic factor and its role in the brain

1997 • 853 citations

Multiple promoters direct tissue-specific expression of the rat BDNF gene

1993 • 851 citations

Kainic acid: a powerful neurotoxic analogue of glutamate

1974 • 710 citations

Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain.

1990 • 700 citations

Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid: A histological study

1980 • 700 citations

Identification of a Signaling Pathway Involved in Calcium Regulation of BDNF Expression

1998 • 687 citations

Increased levels of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis

1991 • 636 citations

Kainic acid as a tool for the study of temporal lobe epilepsy

1981 • 584 citations

Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system

1997 • 500 citations

Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4

1995 • 413 citations

Sensory but not motor neuron deficits in mice lacking NT4 and BDNF

1995 • 381 citations

Corticotropin releasing factor‐like immunoreactivity in the rat brain as revealed by a modified cobalt‐glucose oxidase‐diaminobenzidine method

1987 • 332 citations

Hippocampal damage and kainic acid injection induce a rapid increase in mRNA for BDNF and NGF in the rat brain

1991 • 295 citations

Distribution of Brain‐Derived Neurotrophic Factor in Rats and Its Changes with Development in the Brain

1997 • 291 citations

Brain‐derived Neurotrophic Factor is a Survival Factor for Cultured Rat Cerebellar Granule Neurons and Protects them Against Glutamate‐induced Neurotoxicity

1993 • 287 citations

Brain-Derived Neurotrophic Factor Enhances Long-Term Potentiation in Rat Visual Cortex

1997 • 283 citations

Brain-derived neurotrophic factor administration protects basal forebrain cholinergic but not nigral dopaminergic neurons from degenerative changes after axotomy in the adult rat brain

1992 • 281 citations

Kainic acid-induced seizures stimulate increased expression of nerve growth factor mRNA in rat hippocampus

1991 • 280 citations

BDNF mRNA expression in the developing rat brain following kainic acid-induced seizure activity

1992 • 215 citations

Morphogenetic effect of kainate on adult hippocampal neurons associated with a prolonged expression of brain-derived neurotrophic factor

1995 • 211 citations

Age-related changes in levels of brain-derived neurotrophic factor in selected brain regions of rats, normal mice and senescence-accelerated mice: a comparison to those of nerve growth factor and neurotrophin-3

1998 • 168 citations

Age-related structural changes in the rat hippocampus: correlation with working memory deficiency

1990 • 147 citations

Endogenous BDNF Protein Is Increased in Adult Rat Hippocampus after a Kainic Acid Induced Excitotoxic Insult but Exogenous BDNF Is Not Neuroprotective

1998 • 144 citations

Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers

1997 • 119 citations

Hippocampal calcium-binding protein during commissural kindling-induced epileptogenesis: Progressive decline and effects of anticonvulsants

1984 • 95 citations

Tissue Distribution and Immunocytochemical Localization of Neurotrophin‐3 in the Brain and Peripheral Tissues of Rats

1996 • 95 citations

Synthesis and Accumulation of αB Crystallin in C6 Glioma Cells Is Induced by Agents That Promote the Disassembly of Microtubules

1996 • 66 citations

The Synthesis of Nerve Growth Factor and Brain‐Derived Neurotrophic Factor in Hippocampal and Cortical Neurons Is Regulated by Specific Transmitter Systemsa

1991 • 64 citations

Responses of Heat Shock Proteins hsp27, αB‐Crystallin, and hsp70 in Rat Brain After Kainic Acid‐Induced Seizure Activity

1999 • 64 citations

Sex‐Dependent and Sex‐Independent Distribution of the β‐Subunit of Nerve Growth Factor in the Central Nervous and Peripheral Tissues of Mice

1989 • 56 citations

Early induction of mRNA for calbindin-D28k and BDNF but not NT-3 in rat hippocampus after kainic acid treatment

1997 • 54 citations

Short increase of BDNF messenger RNA triggers kainic acid-induced neuronal hypertrophy in adult mice

1996 • 37 citations

Stimulation of Glutamate Receptors Increases Expression of Brain‐Derived Neurotrophic Factor mRNA in Rat Hippocampus^a

1992 • 33 citations

The expression of voltage-dependent calcium channel beta subunits in human hippocampus

1998 • 19 citations

Autoradiographic analysis of L- and N-type voltage-dependent calcium channel binding in canine brain after global cerebral ischemia/reperfusion

1994 • 17 citations

Reduction of NGF protein level in rat dorsal hippocampus following administration of kainic acid

1992 • 11 citations

An enhanced conversion from tightly bound to loosely bound form of NGF in selected regions of brains from male mice

1998 • 3 citations