Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors in the Failing Human Heart

Elevated Circulating Levels of Tumor Necrosis Factor in Severe Chronic Heart Failure

1990 • 2,566 citations

Negative Inotropic Effects of Cytokines on the Heart Mediated by Nitric Oxide

1992 • 1,635 citations

The Cardiovascular Response of Normal Humans to the Administration of Endotoxin

1989 • 1,096 citations

Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart.

1993 • 708 citations

Increased circulating cytokines in patients with myocarditis and cardiomyopathy.

1994 • 525 citations

Interleukin 1 and tumor necrosis factor inhibit cardiac myocyte beta-adrenergic responsiveness.

1989 • 493 citations

A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity

1989 • 442 citations

Tumor necrosis factor-alpha gene and protein expression in adult feline myocardium after endotoxin administration.

1995 • 436 citations

Basic Mechanisms in Congestive Heart Failure

1994 • 365 citations

Increased concentrations of tumour necrosis factor in "cachectic" patients with severe chronic heart failure.

1991 • 348 citations

Expression and Functional Significance of Tumor Necrosis Factor Receptors in Human Myocardium

1995 • 348 citations

Cellular receptor for 125I-labeled tumor necrosis factor: specific binding, affinity labeling, and relationship to sensitivity.

1985 • 287 citations

A human inhibitor of tumor necrosis factor alpha.

1988 • 264 citations

The tissue distribution of tumor necrosis factor biosynthesis during endotoxemia.

1992 • 228 citations

Pathophysiological correlates of increased serum tumor necrosis factor in patients with congestive heart failure. Relation to nitric oxide-dependent vasodilation in the forearm circulation.

1994 • 219 citations

Mechanism of cytokine inhibition of beta-adrenergic agonist stimulation of cyclic AMP in rat cardiac myocytes. Impairment of signal transduction.

1990 • 215 citations

TUMOUR NECROSIS FACTOR IN BRONCHOPULMONARY SECRETIONS OF PATIENTS WITH ADULT RESPIRATORY DISTRESS SYNDROME

1989 • 202 citations

Tumour necrosis factor alpha in severe congestive cardiac failure.

1993 • 172 citations

Effects of recombinant tumor necrosis factor on proliferation and differentiation of leukemic and normal hemopoietic cells in vitro. Relationship to cell surface receptor.

1986 • 155 citations

Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor.

1992 • 152 citations

Macrophages rapidly internalize their tumor necrosis factor receptors in response to bacterial lipopolysaccharide

1989 • 131 citations

A tumor necrosis factor binding protein is present in human biological fluids

1988 • 122 citations

Measuring circulating cytokines

1993 • 120 citations

Quantification and characterization of high‐affinity membrane receptors for tumor necrosis factor on human leukemic cell lines

1986 • 110 citations

Inhibition of tumor necrosis factor prevents myocardial dysfunction during burn shock

1994 • 109 citations

Nonhematopoietic cells selected for resistance to tumor necrosis factor produce tumor necrosis factor.

1986 • 108 citations

Increased levels of serum neoprotein and decreased production of neutrophil superoxide anions in chronic heart failure with elevated levels of tumor necrosis factor-alpha

1993 • 90 citations

Effect of phorbol esters on down-regulation and redistribution of cell surface receptors for tumor necrosis factor-alpha.

1987 • 84 citations

Human tumor necrosis factor-alpha receptor. Purification by immunoaffinity chromatography and initial characterization.

1988 • 77 citations

Antagonistic control of tumor necrosis factor receptors by protein kinases A and C. Enhancement of TNF receptor synthesis by protein kinase A and transmodulation of receptors by protein kinase C.

1989 • 74 citations

Tumor necrosis factor: receptors on hematopoietic cells

1987 • 68 citations

Biochemical properties of the 75-kDa tumor necrosis factor receptor. Characterization of ligand binding, internalization, and receptor phosphorylation.

1992 • 67 citations

INDUCTION OF TNFα AND TNFβ GENE EXPRESSION IN RAT CARDIAC TRANSPLANTS DURING ALLOGRAFT REJECTION

1993 • 62 citations

Specific induction of 80-kDa tumor necrosis factor receptor shedding in T lymphocytes involves the cytoplasmic domain and phosphorylation.

1993 • 61 citations

Tumor necrosis factor receptors and cytocidal activity are down-regulated by activators of protein kinase C.

1988 • 58 citations

Tumor necrosis factor: Molecular and cellular biology and clinical relevance

1995 • 45 citations

Induction of tumor necrosis factor-alpha and its receptors during differentiation in myeloid leukemic cells along the monocytic pathway. A possible regulatory mechanism for TNF-alpha production.

1990 • 41 citations

Lipoprotein lipase in heart cell cultures is suppressed by bacterial lipopolysaccharide: an effect mediated by production of tumor necrosis factor

1988 • 34 citations

Tumor necrosis factor: receptors on hematopoietic cells

1987 • 30 citations

Down-modulation of cell surface expression of p80 form of the tumor necrosis factor receptor by human immunodeficiency virus-1 tat gene.

1992 • 29 citations

Regulation of two forms of the TNF receptors by phorbol ester and dibutyryl cyclic adenosine 3',5'-monophosphate in human histiocytic lymphoma cell line U-937.

1993 • 25 citations

Immune cytokine inhibition of beta-adrenergic agonist stimulated cyclic AMP generation in cardiac myocytes

1988 • 19 citations

Increased expression and occupancy of receptors for tumour necrosis factor on blood monocytes from tuberculosis patients

1993 • 10 citations

Pitfalls in Measuring Cytokines

1994 • 5 citations

Role of Protein Kinases and Phosphatases in Receptor Biosynthesis, Shedding and Mediation of Cellular Responses to Tumor Necrosis Factor

2015 • 1 citations

PROBLEMS IN CRITICAL CARE: ADVANCES IN INTERVENTIONAL CARDIOLOGY.

1991 • 1 citations

Deleted Work

1955 • 0 citations