Expression of the multidrug resistance-associated protein (MRP) and chemoresistance of human non-small-cell lung cancer cells

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

1992 • 3,039 citations

Cancer statistics, 1993

1993 • 983 citations

Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.

1994 • 777 citations

ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein.

1994 • 435 citations

Chemotherapy of Lung Cancer

1992 • 434 citations

The Leukotriene LTD4 Receptor Antagonist Mk571 Specifically Modulates MRP Associated Multidrug Resistance

1995 • 402 citations

Biology of the multidrug resistance-associated protein, MRP

1996 • 367 citations

Analysis of the expression of MRP, the gene for a new putative transmembrane drug transporter, in human multidrug resistant lung cancer cell lines

1994 • 315 citations

Multifactorial drug resistance in an adriamycin-resistant human small cell lung carcinoma cell line.

1987 • 266 citations

Overlapping phenotypes of multidrug resistance among panels of human cancer-cell lines

1996 • 214 citations

Transport properties of the multidrug resistance‐associated protein (MRP) in human tumour cells

1996 • 194 citations

Multidrug sensitivity phenotype of human lung cancer cells associated with topoisomerase II expression.

1992 • 138 citations

Intracellular distribution and pharmacokinetics of daunorubicin in anthracycline-sensitive and -resistant HL-60 cells.

1989 • 132 citations

Expression of the multidrug resistance-associated protein (MRP) gene in non-small-cell lung cancer

1995 • 107 citations

Multidrug resistance proteins and other drug transport-related resistance to natural product agents

1995 • 83 citations

Expression of the multidrug resistance-associated protein (MRP) gene in primary non-small-cell lung cancer

1996 • 76 citations

Immunohistochemical expression of glutathione S-transferase-π can predict chemotherapy response in patients with nonsmall cell lung carcinoma

1996 • 71 citations

Glutathione and related enzyme activity in human lung cancer cell lines

1988 • 65 citations

Expression of the multidrug resistance‐associated protein (MRP) mRNA and protein in normal peripheral blood and bone marrow haemopoietic cells

1996 • 61 citations

MRP is frequently expressed in human lung-cancer cell lines, in non-small-cell lung cancer and in normal lung

1996 • 61 citations

Possible role of the multidrug resistance-associated protein (MRP) in chemoresistance of human melanoma cells

1997 • 58 citations

Expression of the multidrug resistance-associated protein (MRP) gene in human lung tumours and normal tissue as determined by in situ hybridisation

1994 • 54 citations

Intrinsic MDR‐1 gene and P‐glycoprotein expression in human melanoma cell lines

1994 • 54 citations

Mechanisms of MRP over‐expression in four human lung‐cancer cell lines and analysis of the MRP amplicon

1995 • 53 citations

Multidrug Resistance in the Laboratory and Clinic

1994 • 52 citations

Multidrug resistance-associated protein (MRP) gene expression in human lung cancer.

1996 • 51 citations

Expression of the multidrug-resistance-associated protein (MRP) gene in human colorectal, gastric and non-small-cell lung carcinomas

1996 • 47 citations

Experimental modulation of MRP (multidrug resistanceassociated protein)-mediated resistance

1996 • 43 citations

Mechanisms of drug resistance in human lung cancer cells.

1993 • 42 citations

Preferential expression of the multidurg‐resistance‐associated protein (MRP) in adenocarcinoma of the lung

1995 • 41 citations

Chemotherapy outcomes in advanced non-small-cell lung carcinoma

1994 • 11 citations

Mechanisms for acquired cytotoxic drug resistance in human small cell lung cancer and the potential utilization of resistance modifiers — A review with focus on in vitro studies

1990 • 3 citations