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Hematologic adverse events associated with temozolomide

Data up to Jan 2025

Published2011
Citations55
References32

Total Citations Per Year

Abstract

References (32)

Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

2005 • 18,835 citations

Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project

2009 • 851 citations

Alkylation damage in DNA and RNA—repair mechanisms and medical significance

2004 • 613 citations

Genetics of therapy-related myelodysplasia and acute myeloid leukemia

2008 • 226 citations

Temozolomide in malignant gliomas: current use and future targets

2009 • 186 citations

Gemtuzumab ozogamicin-associated sinusoidal obstructive syndrome (SOS): An overview from the research on adverse drug events and reports (RADAR) project

2006 • 168 citations

DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents

1999 • 146 citations

Acute leukemia as a secondary malignancy in children and adolescents: Current findings and issues

2008 • 113 citations

The impact of thrombocytopenia from temozolomide and radiation in newly diagnosed adults with high-grade gliomas1

2006 • 113 citations

Inherited aplastic anaemias/bone marrow failure syndromes

2008 • 108 citations

Human CD34+ hematopoietic progenitors have low, cytokine-unresponsive O6-alkylguanine-DNA alkyltransferase and are sensitive to O6- benzylguanine plus BCNU

1996 • 85 citations

Human mismatch repair, drug-induced DNA damage, and secondary cancer

2003 • 83 citations

Advances in the understanding of susceptibility to treatment‐related acute myeloid leukaemia

2007 • 83 citations

Risk analysis of severe myelotoxicity with temozolomide: The effects of clinical and genetic factors

2009 • 80 citations

Treatment-related myelodysplastic syndrome after temozolomide for recurrent high-grade glioma

2005 • 78 citations

Treatment-related myelodysplasia/AML in a patient with a history of breast cancer and an oligodendroglioma treated with temozolomide: Case study and review of the literature1

2006 • 66 citations

Clinical features and correlates of gemcitabine‐associated lung injury

2006 • 61 citations

Polymorphic MLH1 and risk of cancer after methylating chemotherapy for Hodgkin lymphoma

2007 • 41 citations

Mutagenic potential of temozolomide in bone marrow cells in vivo

2006 • 41 citations

Aplastic anaemia in patient with glioblastoma multiforme treated with temozolomide

2006 • 40 citations

Prolonged and severe myelosuppression in two patients after low-dose temozolomide treatment- case study and review of literature

2007 • 39 citations

Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide

2007 • 39 citations

Role of O6-methylguanine-DNA methyltransferase in protecting from alkylating agent-induced toxicity and mutations in mice

2006 • 38 citations

Extended exposure to alkylator chemotherapy: delayed appearance of myelodysplasia

2008 • 30 citations

Predicting the myelotoxicity of chemotherapy

2010 • 27 citations

Reciprocal Relationship between O6-Methylguanine-DNA Methyltransferase P140K Expression Level and Chemoprotection of Hematopoietic Stem Cells

2008 • 27 citations

A Rare Case of Aplastic Anemia Caused by Temozolomide

2009 • 25 citations

Prospective Data Mining of Six Products in the US FDA Adverse Event Reporting System

2010 • 24 citations

Change in expression of MGMT during maturation of human monocytes into dendritic cells

2007 • 23 citations

Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma—analysis of O 6-methylguanine-DNA methyltransferase status

2008 • 21 citations

Fatal hematologic toxicity with prolonged continuous administration of temozolomide (TMZ) during radiation therapy (RT) in the treatment of newly-diagnosed glioblastoma multiforme (GBM): Report of a Phase II trial

2005 • 20 citations

Differential inactivation of polymorphic variants of human O6-alkylguanine-DNA alkyltransferase

2007 • 18 citations

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