Hematologic adverse events associated with temozolomide
Data up to Jan 2025
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Abstract
References (32)
Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma
2005 • 18,835 citations
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2008 • 113 citations
The impact of thrombocytopenia from temozolomide and radiation in newly diagnosed adults with high-grade gliomas1
2006 • 113 citations
Inherited aplastic anaemias/bone marrow failure syndromes
2008 • 108 citations
Human CD34+ hematopoietic progenitors have low, cytokine-unresponsive O6-alkylguanine-DNA alkyltransferase and are sensitive to O6- benzylguanine plus BCNU
1996 • 85 citations
Human mismatch repair, drug-induced DNA damage, and secondary cancer
2003 • 83 citations
Advances in the understanding of susceptibility to treatment‐related acute myeloid leukaemia
2007 • 83 citations
Risk analysis of severe myelotoxicity with temozolomide: The effects of clinical and genetic factors
2009 • 80 citations
Treatment-related myelodysplastic syndrome after temozolomide for recurrent high-grade glioma
2005 • 78 citations
Treatment-related myelodysplasia/AML in a patient with a history of breast cancer and an oligodendroglioma treated with temozolomide: Case study and review of the literature1
2006 • 66 citations
Clinical features and correlates of gemcitabine‐associated lung injury
2006 • 61 citations
Polymorphic MLH1 and risk of cancer after methylating chemotherapy for Hodgkin lymphoma
2007 • 41 citations
Mutagenic potential of temozolomide in bone marrow cells in vivo
2006 • 41 citations
Aplastic anaemia in patient with glioblastoma multiforme treated with temozolomide
2006 • 40 citations
Prolonged and severe myelosuppression in two patients after low-dose temozolomide treatment- case study and review of literature
2007 • 39 citations
Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide
2007 • 39 citations
Role of O6-methylguanine-DNA methyltransferase in protecting from alkylating agent-induced toxicity and mutations in mice
2006 • 38 citations
Extended exposure to alkylator chemotherapy: delayed appearance of myelodysplasia
2008 • 30 citations
Predicting the myelotoxicity of chemotherapy
2010 • 27 citations
Reciprocal Relationship between O6-Methylguanine-DNA Methyltransferase P140K Expression Level and Chemoprotection of Hematopoietic Stem Cells
2008 • 27 citations
A Rare Case of Aplastic Anemia Caused by Temozolomide
2009 • 25 citations
Prospective Data Mining of Six Products in the US FDA Adverse Event Reporting System
2010 • 24 citations
Change in expression of MGMT during maturation of human monocytes into dendritic cells
2007 • 23 citations
Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma—analysis of O 6-methylguanine-DNA methyltransferase status
2008 • 21 citations
Fatal hematologic toxicity with prolonged continuous administration of temozolomide (TMZ) during radiation therapy (RT) in the treatment of newly-diagnosed glioblastoma multiforme (GBM): Report of a Phase II trial
2005 • 20 citations
Differential inactivation of polymorphic variants of human O6-alkylguanine-DNA alkyltransferase
2007 • 18 citations
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