Risk analysis of severe myelotoxicity with temozolomide: The effects of clinical and genetic factors

Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

2005 • 18,835 citations

2006 Update of Recommendations for the Use of White Blood Cell Growth Factors: An Evidence-Based Clinical Practice Guideline

2006 • 1,657 citations

The Human Hepatic Cytochromes P450 Involved in Drug Metabolism

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NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms

2000 • 604 citations

DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma.

1998 • 413 citations

Changing Paradigms—An Update on the Multidisciplinary Management of Malignant Glioma

2006 • 371 citations

Chapter 1 Gender Differences in Pharmacological Response

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Epidemiology of drug exposure and adverse drug reactions in two Swiss departments of internal medicine

2000 • 304 citations

Specificity of human UDP-Glucuronosyltransferases and xenobiotic glucuronidation

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Gender Differences in Adverse Drug Reactions

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The impact of thrombocytopenia from temozolomide and radiation in newly diagnosed adults with high-grade gliomas1

2006 • 113 citations

Is Dose Normalization to Weight or Body Surface Area Useful in Adults?

1990 • 102 citations

Population Pharmacokinetic-Pharmacodynamic Model for Neutropenia with Patient Subgroup Identification: Comparison across Anticancer Drugs

2006 • 86 citations

Treatment-related myelodysplasia/AML in a patient with a history of breast cancer and an oligodendroglioma treated with temozolomide: Case study and review of the literature1

2006 • 66 citations

Quantitative trait locus analysis reveals two intragenic sites that influence O6 -alkylguanine-DNA alkyltransferase activity in peripheral blood mononuclear cells

2005 • 56 citations

Pharmacokinetics of Chemotherapy in the Older Patient

2007 • 51 citations

Prolonged and severe myelosuppression in two patients after low-dose temozolomide treatment- case study and review of literature

2007 • 39 citations

Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide

2007 • 39 citations

Obesity is not associated with increased myelosuppression in patients receiving chemotherapy for breast cancer

2006 • 32 citations

Fatal hematologic toxicity with prolonged continuous administration of temozolomide (TMZ) during radiation therapy (RT) in the treatment of newly-diagnosed glioblastoma multiforme (GBM): Report of a Phase II trial

2005 • 20 citations