Spontaneous sleep in mice with targeted disruptions of neuronal or inducible nitric oxide synthase genes

Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

1994 • 1,578 citations

Targeted disruption of the neuronal nitric oxide synthase gene

1993 • 1,300 citations

Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

1996 • 895 citations

Altered circadian activity rhythms and sleep in mice devoid of prion protein

1996 • 655 citations

Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase

1995 • 603 citations

Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.

1995 • 585 citations

Regulation of Endothelial Nitric Oxide Synthase: Location, Location, Location

2002 • 542 citations

The role of tumour necrosis factor, interleukin 6, interferon-γ and inducible nitric oxide synthase in the development and pathology of the nervous system

1998 • 377 citations

Does Nitric Oxide Play a Critical Role in Viral Infections?

1998 • 273 citations

Magnocellular Nuclei of the Basal Forebrain: Substrates of Sleep and Arousal Regulation

1995 • 272 citations

Multiple output pathways of the basal forebrain: organization, chemical heterogeneity, and roles in vigilance

2000 • 255 citations

Resetting the Biological Clock: Mediation of Nocturnal CREB Phosphorylation via Light, Glutamate, and Nitric Oxide

1997 • 243 citations

Expression and function of inducible nitric oxide synthase in neurons

2001 • 224 citations

Neurotrophins Live or Let Die: Does p75NTR Decide?

1997 • 211 citations

Extracellular adenosine levels in neostriatum and hippocampus during rest and activity periods of rats

1996 • 182 citations

The Mechanism of Action of Cytokines to Control the Release of Hypothalamic and Pituitary Hormones in Infection

2000 • 168 citations

Pontine Nitric Oxide Modulates Acetylcholine Release, Rapid Eye Movement Sleep Generation, and Respiratory Rate

1997 • 168 citations

From slow waves to sleep homeostasis: new perspectives.

2001 • 153 citations

Mice, gene targeting and behaviour: more than just genetic background

1996 • 150 citations

Inhibition of nitric oxide synthesis inhibits rat sleep

1994 • 133 citations

Inhibition of nitric oxide synthesis suppresses sleep in rabbits

1994 • 128 citations

Pontine structures and mechanisms involved in the generation of paradoxical (REM) sleep.

2001 • 124 citations

Chapter 1 Regulation of neuronal nitric oxide synthase and identification of novel nitric oxide signaling pathways

1998 • 119 citations

Brain iNOS: current understanding and clinical implications

1999 • 119 citations

Humoral regulation of physiological sleep: cytokines and GHRH

1999 • 118 citations

The effects of immunolesions of nerve growth factor-receptive neurons by 192 IgG-saporin on sleep

1996 • 104 citations

Nitric Oxide Production in Rat Thalamus Changes with Behavioral State, Local Depolarization, and Brainstem Stimulation

1997 • 98 citations

Endogenous and exogenous nitric oxide in the pedunculopontine tegmentum induces sleep

1997 • 93 citations

Nitric Oxide Donors SIN-1 and SNAP Promote Nonrapid-Eye-Movement Sleep in Rats

1996 • 88 citations

The Neuronal Nitric Oxide Synthase Gene Is Critically Involved in Neurobehavioral Effects of Alcohol

2002 • 84 citations

Chapter 2 Genetic analysis of NOS isoforms using nNOS and eNOS knockout animals

1998 • 76 citations

Nitric oxide and sleep in the rat: a puzzling relationship

1999 • 75 citations

Nitric Oxide-Stimulated Increase in Extracellular Adenosine Accumulation in Rat Forebrain Neurons in Culture Is Associated with ATP Hydrolysis and Inhibition of Adenosine Kinase Activity

2000 • 73 citations

Circadian variation of nitric oxide synthase activity and cytosolic protein levels in rat brain

1996 • 72 citations

Carbon Monoxide and Nitric Oxide: Interacting Messengers in Muscarinic Signaling to the Brain's Circadian Clock

2001 • 64 citations

Sleep and nitric: oxide: effects of 7-nitro indazole, inhibitor of brain nitric oxide synthase

1996 • 61 citations

Both the Neuronal and Inducible Isoforms Contribute to Upregulation of Retinal Nitric Oxide Synthase Activity by Brain-Derived Neurotrophic Factor

1999 • 59 citations

Presence of neuronal nitric oxide synthase in the suprachiasmatic nuclei of mouse and rat

1996 • 54 citations

Nitric oxide synthase inhibition decreases pontine acetylcholine release

1995 • 54 citations

Microinjection of Neostigmine into the Pontine Reticular Formation of C57BL/6J Mouse Enhances Rapid Eye Movement Sleep and Depresses Breathing

2002 • 53 citations

Involvement of nitric oxide, cyclic GMP and phosphodiesterase 5 in excitatory amino acid and GABA release in the nucleus accumbens evoked by activation of the hippocampal fimbria

2002 • 50 citations

Endothelial and neuronal nitric oxide synthases are present in the suprachiasmatic nuclei of Syrian hamsters and rats

2000 • 47 citations

Endogenous nitric oxide in the rat pons promotes sleep

1999 • 47 citations

Activity-Dependent Nitric Oxide Concentration Dynamics in the Laterodorsal Tegmental Nucleus In Vitro

2001 • 47 citations

Vigilance and EEG power in rats: effects of potent inhibitors of the neuronal nitric oxide synthase

1997 • 41 citations

Systemic injection of a nitric oxide synthase inhibitor suppresses sleep responses to sleep deprivation in rats

2000 • 37 citations

Role of nitric oxide in sleep regulation: effects of l-NAME, an inhibitor of nitric oxide synthase, on sleep in rats

1999 • 36 citations

The Nitric Oxide Synthase InhibitorN^G-Nitro-l-Arginine Increases Basal Forebrain Acetylcholine Release during Sleep and Wakefulness

2002 • 32 citations

Increase of waking and reduction of NREM and REM sleep after nitric oxide synthase inhibition: prevention with GABAA or adenosine A1 receptor agonists

2001 • 28 citations

Localization of nitric oxide-synthesizing neurons sending projections to the dorsal raphe nucleus of the rat

1998 • 21 citations

Granulocyte-Macrophage Colony-Stimulating Factor Modulates Rapid Eye Movement (REM) Sleep and Non-REM Sleep in Rats

2000 • 17 citations

5-Hydroxyindoles compounds and nitric oxide voltammetric detection in the rat brain: changes occurring throughout the sleep-wake cycle

1998 • 15 citations

Pontine injections of nitric oxide synthase inhibitor l-name consolidate episodes of rem sleep in the rat.

1998 • 12 citations