Microinjection of Neostigmine into the Pontine Reticular Formation of C57BL/6J Mouse Enhances Rapid Eye Movement Sleep and Depresses Breathing

The Mouse Brain in Stereotaxic Coordinates

2001 • 12,804 citations

Principles and Practice of Sleep Medicine

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Narcolepsy in orexin Knockout Mice

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Guidelines for the Multiple Sleep Latency Test (MSLT): A Standard Measure of Sleepiness

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An h Per2 Phosphorylation Site Mutation in Familial Advanced Sleep Phase Syndrome

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Genetic Ablation of Orexin Neurons in Mice Results in Narcolepsy, Hypophagia, and Obesity

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Mouse genetics: concepts and applications

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A CLOCK Polymorphism Associated with Human Diurnal Preference

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Behavioral and Anatomical Correlates of Chronic Episodic Hypoxia during Sleep in the Rat

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The Homeostatic Regulation of Sleep Need Is under Genetic Control

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Mutation of the Ca2+ Channel β Subunit Gene Cchb4 Is Associated with Ataxia and Seizures in the Lethargic (lh) Mouse

1997 • 399 citations

A cholinergic mechanism in the brainstem reticular formation: Induction of paradoxical sleep

1964 • 394 citations

The Promise of Comparative Genomics in Mammals

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Sleep and Sleep Regulation in Normal and Prion Protein-Deficient Mice

1997 • 296 citations

Determinants of ventilatory instability and variability

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Genetic variation in EEG activity during sleep in inbred mice

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Motoneuron properties during motor inhibition produced by microinjection of carbachol into the pontine reticular formation of the decerebrate cat

1987 • 277 citations

Diazepam-induced changes in sleep: Role of the α1 GABA_Areceptor subtype

2001 • 227 citations

A neuroanatomical gradient in the pontine tegmentum for the cholinoceptive induction of desynchronized sleep signs

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Differential control of ventilation among inbred strains of mice

1994 • 208 citations

A Novel Gene Causing a Mendelian Audiogenic Mouse Epilepsy

2001 • 185 citations

Key Role of 5-HT_1BReceptors in the Regulation of Paradoxical Sleep as Evidenced in 5-HT_1BKnock-Out Mice

1999 • 172 citations

Pontine Nitric Oxide Modulates Acetylcholine Release, Rapid Eye Movement Sleep Generation, and Respiratory Rate

1997 • 168 citations

Cholinergic brainstem mechanisms of REM sleep in the rat

1986 • 163 citations

Microinjection of neostigmine into the pontine reticular formation of cats enhances desynchronized sleep signs.

1984 • 160 citations

Induction of rapid eye movement sleep by carbachol infusion into the pontine reticular formation in the rat

1995 • 157 citations

Brainstem sites for the carbachol elicitation of the hippocampal theta rhythm in the rat

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Induction of both emotional behavior and a novel form of REm sleep by chemical stimulation applied to cat mesencephalon

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Pedunculopontine stimulation alters respiration and increases ACh release in the pontine reticular formation

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The Promise of Comparative Genomics in Mammals

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A model of sleep-disordered breathing in the C57BL/6J mouse

2001 • 126 citations

Genetic Studies of Sleep in Mice

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EEG AND BEHAVIORAL CHANGES FOLLOWING MICROINJECTIONS OF ACETYLCHOLINE AND ADRENALINE IN THE BRAIN STEM OF CATS.

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Continuous pontine cholinergic microinfusion via mini-pump induces sustained alterations in rapid eye movement (REM) sleep

1986 • 111 citations

Transgenic mouse models of Alzheimer’s disease

2000 • 101 citations

Enhancement of rapid eye movement sleep in the rat by cholinergic and adenosinergic agonists infused into the pontine reticular formation

1998 • 101 citations

Carbachol models of REM sleep: recent developments and new directions.

2001 • 100 citations

The carbachol-induced enhancement of desynchronized sleep signs is dose dependent and antagonized by centrally administered atropine

1989 • 100 citations

Modulation of Brain Gene Expression during Sleep and Wakefulness A Review of Recent Findings

2001 • 88 citations

Transgenic mouse models of Alzheimer's disease

2001 • 84 citations

Pontine Microinjection of Carbachol Does Not Reliably Enhance Paradoxical Sleep in Rats

1997 • 79 citations

Localization of candidate genomic regions influencing paradoxical sleep in mice

1997 • 76 citations

Ventilatory behavior after hypoxia in C57BL/6J and A/J mice

2001 • 71 citations

Central Sleep Apnea-Hypopnea Syndrome in Heart Failure: Prevalence, Impact, and Treatment

1996 • 71 citations

Sleep Science: Integrating Basic Research and Clinical Practice

1997 • 67 citations

M2 Muscarinic Receptor Subtype in the Feline Medial Pontine Reticular Formation Modulates the Amount of Rapid Eye Movement Sleep

1999 • 66 citations

Cholinergic Mechanisms Regulating REM Sleep

1997 • 62 citations

Behavioral state-specific inhibitory postsynaptic potentials impinge on cat lumbar motoneurons during active sleep

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Inheritance of ventilatory behavior in rodent models

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Quantitative trait loci approach to the genetics of sleep in recombinant inbred mice

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Location and quantification of muscarinic receptor subtypes in rat pons: implications for REM sleep generation

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Selective blockade of different brain stem muscarinic receptor subtypes: effects on the sleep-wake cycle

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Circadian rhythms of sleep and wakefulness in mice: analysis using long-term automated recording of sleep

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Sleep and activity rhythms in mice: A description of circadian patterns and unexpected disruptions in sleep

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Selected Contribution: Regulation of sleep-wake states in response to intermittent hypoxic stimuli applied only in sleep

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Differential cholinergic activation of G proteins in rat and mouse brainstem: Relevance for sleep and nociception

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Cholinoceptive pontine reticular mechanisms cause state-dependent respiratory changes in the cat

1989 • 41 citations

State‐dependent hypotonia in posterior cricoarytenoid muscles of the larynx caused by cholinoceptive reticular mechanisms

1989 • 34 citations

Neocortical and hippocampal electrical activities are similar in spontaneous and cholinergic-induced REM sleep

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Effect of sleep/wake state on arterial blood pressure in genetically identical mice

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Genetic control of ventilation: What are we learning from murine models?

1999 • 24 citations

Respiratory nuclei share synaptic connectivity with pontine reticular regions regulating REM sleep

1995 • 24 citations

The Control of Motoneurons during Sleep

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Developmental patterns of NF-κB activation during acute hypoxia in the caudal brainstem of the rat

2001 • 19 citations

Effect of REM Sleep Deprivation on Sleep Apneas in Rats

1996 • 18 citations

Effects of clonidine and α-methyl-p-tyrosine on the carbachol stimulation of paradoxical sleep

1994 • 13 citations