Chimaeric nicotinic–serotonergic receptor combines distinct ligand binding and channel specificities

A general method ofin vitropreparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

1988 • 2,410 citations

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

1993 • 1,455 citations

Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine

1986 • 1,255 citations

Primary Structure And Functional Expression of the 5HT ₃ Receptor, A Serotonin-gated Ion Channel

1991 • 976 citations

Membrane protein folding and oligomerization: the two-stage model

1990 • 927 citations

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

1990 • 923 citations

Primary structures of β- and δ-subunit precursors of Torpedo californica acetylcholine receptor deduced from cDNA sequences

1983 • 527 citations

Brain α-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily

1990 • 471 citations

Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors

1992 • 465 citations

Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic

1992 • 420 citations

Nucleotide and deduced amino acid sequences of Torpedo californica acetylcholine receptor gamma subunit.

1983 • 412 citations

Chloride current induced by injection of calcium into Xenopus oocytes.

1984 • 395 citations

Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor.

1993 • 389 citations

Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain.

1983 • 332 citations

Location of a δ-subunit region determining ion transport through the acetylcholine receptor channel

1986 • 315 citations

Amino acids of the Torpedo marmorata acetylcholine receptor .alpha. subunit labeled by a photoaffinity ligand for the acetylcholine binding site

1988 • 314 citations

The ion channel of the nicotinic acetylcholine receptor is formed by the homologous helices M II of the receptor subunits

1986 • 313 citations

Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine.

1986 • 296 citations

Identification of a novel amino acid alpha-tyrosine 93 within the cholinergic ligands-binding sites of the acetylcholine receptor by photoaffinity labeling. Additional evidence for a three-loop model of the cholinergic ligands-binding sites.

1990 • 247 citations

Structure of nicotinic acetylcholine receptors

1993 • 234 citations

Point mutations affecting antagonist affinity and agonist dependent gating of GABAA receptor channels.

1992 • 203 citations

Potentiation of nicotinic receptor response by external calcium in rat central neurons

1992 • 191 citations

A single amino acid exchange alters the pharmacology of neonatal rat glycine receptor subunit

1990 • 183 citations

5‐Hydroxytryptamine receptors of visceral primary afferent neurones on rabbit nodose ganglia

1982 • 147 citations

Single amino acid substitution affects desensitization of the 5-hydroxytryptamine type 3 receptor expressed in Xenopus oocytes.

1993 • 130 citations

Ion permeation through 5-hydroxytryptamine-gated channels in neuroblastoma N18 cells.

1990 • 125 citations

Pharmacological properties of the homomeric α7 receptor

1992 • 117 citations

Promoter-cDNA-directed heterologous protein expression in Xenopus laevis oocytes.

1992 • 116 citations

Antagonism of ligand-gated ion channel receptors: two domains of the glycine receptor alpha subunit form the strychnine-binding site.

1992 • 111 citations

Extracellular domains mediating ɛ subunit interactions of muscle acetylcholine receptor

1991 • 94 citations

5-HT3 receptor channels in dissociated rat superior cervical ganglion neurons.

1992 • 91 citations

Electrophysiology of Neuronal Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes following Nuclear Injection of Genes or cDNAs

1991 • 91 citations

Divalent cations modulate 5-HT3 receptor-induced currents in N1E-115 neuroblastoma cells

1988 • 83 citations

Sequences on the N-terminus of ACh receptor subunits regulate their assembly

1992 • 33 citations

Expression of mouse-Torpedo acetylcholine receptor subunit chimeras and hybrids in Xenopus oocytes

1987 • 24 citations