Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

On the nature of allosteric transitions: A plausible model

1965 • 8,699 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence

1982 • 730 citations

Acetylcholine Receptor: Complex of Homologous Subunits

1980 • 594 citations

Primary structures of β- and δ-subunit precursors of Torpedo californica acetylcholine receptor deduced from cDNA sequences

1983 • 527 citations

Path of the polypeptide in bacteriorhodopsin.

1980 • 366 citations

The permeability of the endplate channel to organic cations in frog muscle.

1980 • 362 citations

Structure and function of an acetylcholine receptor

1982 • 281 citations

The acetylcholine receptor: an "allosteric" membrane protein.

1979 • 256 citations

Studies of the composition of purified Torpedo californica acetylcholine receptor and of its subunits

1979 • 193 citations

On the Hydrophobic Nature of Signal Sequences

1981 • 193 citations

Structural studies of a membrane-bound acetylcholine receptor from Torpedo californica

1977 • 183 citations

The molecular cloning and characterisation of cDNA coding for the α subunit of the acetyl-choline receptor

1982 • 176 citations

Membrane Proteins. The Amino Acid Composition of Membrane-Penetrating Segments

1981 • 157 citations

In vitro synthesis, glycosylation, and membrane insertion of the four subunits of Torpedo acetylcholine receptor.

1981 • 147 citations

A morphological study of the cholinergic receptor protein from Torpedo marmorata in its membrane environment and in its detergent-extracted purified form

1978 • 130 citations

Transmembrane Orientation of Proteins Present in Acetylcholine Receptor‐Rich Membranes from Torpedo marmorata Studied by Selective Proteolysis

1980 • 120 citations

Ultraviolet light-induced labeling by noncompetitive blockers of the acetylcholine receptor from Torpedo marmorata.

1981 • 113 citations

[6] Specific labeling of 3′ termini with T4 DNA polymerase

1980 • 102 citations

Molecular cloning of cDNA coding for the gamma subunit of Torpedo acetylcholine receptor.

1982 • 102 citations

Reconstitution of a Functional Acetylcholine Receptor

1980 • 74 citations

Functional Equivalence of Monomeric and Dimeric Forms of Purified Acetylcholine Receptors from Torpedo californica in Reconstituted Lipid Vesicles

1980 • 71 citations

The amino‐terminal sequence of the 40 000 molecular weight subunit of the acetylcholine receptor protein from Torpedo marmorata

1979 • 58 citations

Reconstitution of a Functional Acetylcholine Receptor

1981 • 58 citations

Identification of a cDNA clone coding for the acetylcholine binding subunit of Torpedo marmorata acetylcholine receptor.

1982 • 56 citations

Reconstitution of acetylcholine receptor function using purified receptor protein

1981 • 37 citations

Specificity and localization of the acetylcholine receptor kinase.

1982 • 27 citations

[The high affinity binding site for chlorpromazine is present only as a single copy per cholinergic receptor molecule and is shared by four polypeptide chains].

1982 • 5 citations