Frequent overexpression of the cyclin D1 oncogene in invasive lobular carcinoma of the breast.

The retinoblastoma protein and cell cycle control

1995 • 4,873 citations

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

1984 • 4,180 citations

G1 phase progression: Cycling on cue

1994 • 2,706 citations

Cyclin D1 is a nuclear protein required for cell cycle progression in G1.

1993 • 1,605 citations

A novel cyclin encoded by a bcl1-linked candidate oncogene

1991 • 1,286 citations

Cyclin D1 provides a link between development and oncogenesis in the retina and breast

1995 • 1,017 citations

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

1994 • 982 citations

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

1995 • 894 citations

CDK-Independent Activation of Estrogen Receptor by Cyclin D1

1997 • 698 citations

Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

1995 • 681 citations

Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining.

1994 • 673 citations

Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein.

1996 • 453 citations

Estrogen-induced Activation of Cdk4 and Cdk2 during G1-S Phase Progression Is Accompanied by Increased Cyclin D1 Expression and Decreased Cyclin-dependent Kinase Inhibitor Association with Cyclin E-Cdk2

1997 • 438 citations

Infiltrating lobular carcinoma of the breast: Clinicopathologic analysis of 975 cases with reference to data on conservative therapy and metastatic patterns

1996 • 410 citations

D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BCL-1.

1991 • 376 citations

Molecular cloning and chromosomal mapping of DNA rearranged with the parathyroid hormone gene in a parathyroid adenoma.

1989 • 367 citations

17beta-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells.

1996 • 344 citations

Overexpression of cyclin D mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions

1995 • 334 citations

Overexpression of the Integrin-linked Kinase Promotes Anchorage-independent Cell Cycle Progression

1997 • 259 citations

Estrogen regulates activity of cyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells.

1996 • 233 citations

Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells.

1997 • 227 citations

Immunohistochemical localization of integrins in the normal, hyperplastic, and neoplastic breast. Correlations with their functions as receptors and cell adhesion molecules.

1991 • 224 citations

Determination of the prognostic value of cyclin D1 overexpression in breast cancer.

1995 • 215 citations

A clinicopathological study on overexpression of cyclin D1 and of p53 in a series of 248 patients with operable breast cancer

1996 • 181 citations

Cyclin D1 (Bcl-1, PRAD1) protein expression in low-grade B-cell lymphomas and reactive hyperplasia.

1994 • 173 citations

Integrins and their accessory adhesion molecules in mammary carcinomas: Loss of polarization in poorly differentiated tumors

1992 • 170 citations

Proto-oncogene amplification and human breast tumor phenotype

1990 • 154 citations

Increased expression of cyclin D1 in a murine mammary epithelial cell line induces p27kip1, inhibits growth, and enhances apoptosis.

1996 • 145 citations

Cyclin D1 (PRAD1) protein expression in breast cancer: approximately one-third of infiltrating mammary carcinomas show overexpression of the cyclin D1 oncogene.

1995 • 127 citations

Proto-oncogene abnormalities in human breast cancer: c-ERBB-2 amplification does not correlate with recurrence of disease.

1989 • 127 citations

Immunohistochemistry of Cyclin D1 in Human Breast Cancer

1994 • 125 citations

Association of INT2/HST1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis

1991 • 124 citations

Differential regulation of growth and invasiveness of MCF-7 breast cancer cells by antiestrogens.

1988 • 123 citations

Gene amplification on chromosome band 11q13 and oestrogen receptor status in breast cancer

1990 • 118 citations

Chromosome 11 translocation breakpoints at the PRAD1/cyclin D1 gene locus in centrocytic lymphoma.

1993 • 116 citations

Overexpression of cyclin D1 enhances gene amplification.

1996 • 114 citations

The amplification unit on chromosome 11q13 in aggressive primary human breast tumors entails the bcl-1, int-2 and hst loci.

1989 • 114 citations

Increased expression of the P27KIP1 protein in human esophageal cancer cell lines that over-express cyclin D1

1997 • 76 citations

Expression of the retinoblastoma protein in low-grade B-cell lymphoma: relationship to cyclin D1

1996 • 57 citations

The cyclin D1/PRAD1 oncogene in human neoplasia.

1995 • 52 citations

Immunohistochemical Analysis of Cyclin D1 Protein in Hematopoietic Neoplasms with Special Reference to Mantle Cell Lymphoma

1994 • 51 citations

Elimination of Cyclin D1 in Vertebrate Cells Leads to an Altered Cell Cycle Phenotype, Which Is Rescued by Overexpression of Murine Cyclins D1, D2, or D3 but Not by a Mutant Cyclin D1

1997 • 48 citations

The Positive Nuclear Staining Observed with Monoclonal Antibody against PRAD1/Cyclin D1 Correlates with mRNA Expression in Mantle Cell Lymphoma

1995 • 43 citations

Immunohistochemical detection and gene amplification of cyclin D1 in mammary infiltrating ductal carcinoma.

1996 • 36 citations