Quantitative analysis of glutamate transporter mRNA expression in prefrontal and primary visual cortex in normal and schizophrenic brain

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

2001 • 156,143 citations

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

2002 • 18,672 citations

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Molecular Beacons: Probes that Fluoresce upon Hybridization

1996 • 4,073 citations

Glutamate uptake

2001 • 3,867 citations

Psychopharmacology: The Fourth Generation of Progress

1995 • 2,920 citations

Kinetic PCR Analysis: Real-time Monitoring of DNA Amplification Reactions

1993 • 2,177 citations

Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1986 • 2,026 citations

Epilepsy and Exacerbation of Brain Injury in Mice Lacking the Glutamate Transporter GLT-1

1997 • 1,715 citations

Localization of neuronal and glial glutamate transporters

1994 • 1,668 citations

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis

1995 • 1,430 citations

Primary structure and functional characterization of a high-affinity glutamate transporter

1992 • 1,319 citations

Cloning and expression of a rat brain L-glutamate transporter

1992 • 1,230 citations

Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain.

1992 • 1,185 citations

An excitatory amino-acid transporter with properties of a ligand-gated chloride channel

1995 • 1,124 citations

NMDA receptor hypofunction model of schizophrenia

1999 • 1,007 citations

The Emerging Role of Glutamate in the Pathophysiology and Treatment of Schizophrenia

2001 • 915 citations

Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance

1997 • 909 citations

Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations

1995 • 884 citations

Abnormally High Neuronal Density in the Schizophrenic Cortex

1995 • 866 citations

Glutamate transporters in glial plasma membranes: Highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry

1995 • 821 citations

Thermodynamic basis of the enhanced specificity of structured DNA probes

1999 • 652 citations

Brain Glutamate Transporter Proteins Form Homomultimers

1996 • 471 citations

Glutamate receptor expression in schizophrenic brain

2000 • 401 citations

Cytoarchitectonic Definition of Prefrontal Areas in the Normal Human Cortex: I. Remapping of Areas 9 and 46 using Quantitative Criteria

1995 • 398 citations

Chapter 6 Glutamate receptors and the induction of excitotoxic neuronal death

1994 • 387 citations

Symptoms, Cognitive Functioning, and Adaptive Skills in Geriatric Patients With Lifelong Schizophrenia: A Comparison Across Treatment Sites

1998 • 341 citations

Glutamate Transporter Alterations in Alzheimer Disease Are Possibly Associated with Abnormal APP Expression

1997 • 325 citations

Severity of symptoms in chronically institutionalized geriatric schizophrenic patients

1995 • 307 citations

The Glutamate Transporter GLT1a Is Expressed in Excitatory Axon Terminals of Mature Hippocampal Neurons

2004 • 255 citations

Review Article The family of sodium-dependent glutamate transporters: a focus on the GLT-1/EAAT2 subtype

1998 • 239 citations

Glutamate transporter gene expression in amyotrophic lateral sclerosis motor cortex

1996 • 237 citations

Chronic restraint stress up-regulates GLT-1 mRNA and protein expression in the rat hippocampus: Reversal by tianeptine

2004 • 218 citations

Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia

1998 • 209 citations

Evidence for a compromised dorsolateral prefrontal cortical parallel circuit in schizophrenia

2000 • 206 citations

Expression of a Variant Form of the Glutamate Transporter GLT1 in Neuronal Cultures and in Neurons and Astrocytes in the Rat Brain

2002 • 205 citations

Striatal Excitatory Amino Acid Transporter Transcript Expression in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

2002 • 189 citations

Expression of Excitatory Amino Acid Transporter Transcripts in the Thalamus of Subjects With Schizophrenia

2001 • 187 citations

N-Methyl-<scp>d</scp>-Aspartic Acid Receptor Expression in the Dorsolateral Prefrontal Cortex of Elderly Patients With Schizophrenia

2001 • 186 citations

Cellular and Regional Distribution of the Glutamate Transporter GLAST in the CNS of Rats: NonradioactiveIn SituHybridization and Comparative Immunocytochemistry

1997 • 174 citations

Alzheimer Disease and Related Neurodegenerative Diseases in Elderly Patients With Schizophrenia

1998 • 174 citations

Impaired prefrontal inhibition in schizophrenia: relevance for cognitive dysfunction

2002 • 160 citations

A splice variant of glutamate transporter GLT1/EAAT2 expressed in neurons: cloning and localization in rat nervous system

2002 • 153 citations

Expression of the glutamate transporter GLT1 in neural cells of the rat central nervous system: Non-radioactive in situ hybridization and comparative immunocytochemistry

1996 • 150 citations

Comparative analysis of glutamate transporter expression in rat brain using differential double in situ hybridization

1998 • 149 citations

Abnormal Glutamate Transport Function in Mutant Amyloid Precursor Protein Transgenic Mice

2000 • 141 citations

Persistence of Haloperidol in Human Brain Tissue

1999 • 136 citations

Altered expression of the glutamate transporter EAAT2b in neurological disease

2004 • 133 citations

Increased expression of the astrocytic glutamate transporter GLT‐1 in the prefrontal cortex of schizophrenics

2004 • 125 citations

Aberrant Expression of the Glutamate Transporter Excitatory Amino Acid Transporter 1 (EAAT1) in Alzheimer's Disease

2002 • 122 citations

Receptor mechanisms and circuitry underlying NMDA antagonist neurotoxicity

2002 • 121 citations

Differential distribution of the glutamate transporters GLT1 and rEAAC1 in rat cerebral cortex and thalamus: an in situ hybridization analysis

1997 • 113 citations

MRI Assessment of Gray and White Matter Distribution in Brodmann’s Areas of the Cortex in Patients With Schizophrenia With Good and Poor Outcomes

2003 • 112 citations

GAD67 and GAD65 mRNA and protein expression in cerebrocortical regions of elderly patients with schizophrenia

2004 • 101 citations

Cloning, transport properties, and differential localization of two splice variants of GLT‐1 in the rat CNS: Implications for CNS glutamate homeostasis

2003 • 98 citations

Implications for Altered Glutamate and GABA Metabolism in the Dorsolateral Prefrontal Cortex of Aged Schizophrenic Patients

2002 • 96 citations

The expression of glutamate transporter GLT-1 in the rat cerebral cortex is down-regulated by the antipsychotic drug clozapine

2001 • 95 citations

Morphine Withdrawal Increases Glutamate Uptake and Surface Expression of Glutamate Transporter GLT1 at Hippocampal Synapses

2003 • 95 citations

Gene expression of metabotropic glutamate receptor 5 and excitatory amino acid transporter 2 in the schizophrenic hippocampus

2000 • 91 citations

mRNA expression of AMPA receptors and AMPA receptor binding proteins in the cerebral cortex of elderly schizophrenics

2005 • 85 citations

RNA editing and alternative splicing of human serotonin 2C receptor in schizophrenia

2003 • 75 citations

Glutamatergic neurotransmission involves structural and clinical deficits of schizophrenia

1998 • 74 citations

Decreased gene expression of glial and neuronal glutamate transporters after chronic antipsychotic treatment in rat brain

2003 • 65 citations

Loss of glial glutamate transporters and induction of neuronal expression of GLT-1B in the hypoxic neonatal pig brain

2004 • 60 citations

Distribution of two splice variants of the glutamate transporter GLT‐1 in rat brain and pituitary

2002 • 59 citations

Neuron-specific human glutamate transporter: molecular cloning, characterization and expression in human brain

1994 • 59 citations

Clozapine reduces GLT-1 expression and glutamate uptake in astrocyte cultures

2005 • 56 citations

Chronic neuroleptic treatment alters expression of glial glutamate transporter GLT-1 mRNA in the striatum

1998 • 56 citations

Excitatory Amino Acid Transporter EAAT‐2 in Tangle‐bearing Neurons in Alzheimer's Disease

2002 • 48 citations

Antipsychotic regulation of hippocampal dopamine receptor messenger RNA expression

1997 • 30 citations

Complementary neuronal and glial expression of two high-affinity glutamate transporter GLT1/EAAT2 forms in rat cerebral cortex

2003 • 19 citations

Neurobiology of glutamatergic abnormalities in schizophrenia

2003 • 13 citations