Expression of Excitatory Amino Acid Transporter Transcripts in the Thalamus of Subjects With Schizophrenia

Subanesthetic Effects of the Noncompetitive NMDA Antagonist, Ketamine, in Humans

1994 • 3,182 citations

Recent advances in the phencyclidine model of schizophrenia

1991 • 2,886 citations

Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate

1996 • 2,470 citations

Epilepsy and Exacerbation of Brain Injury in Mice Lacking the Glutamate Transporter GLT-1

1997 • 1,715 citations

Localization of neuronal and glial glutamate transporters

1994 • 1,668 citations

The Neuropsychopharmacology of Phencyclidine From NMDA Receptor Hypofunction to the Dopamine Hypothesis of Schizophrenia

1999 • 1,300 citations

"Cognitive Dysmetria" as an Integrative Theory of Schizophrenia: A Dysfunction in Cortical-Subcortical-Cerebellar Circuitry?

1998 • 1,145 citations

Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex

1994 • 988 citations

Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance

1997 • 909 citations

Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations

1995 • 884 citations

Thalamic Abnormalities in Schizophrenia Visualized Through Magnetic Resonance Image Averaging

1994 • 699 citations

Aberrant RNA Processing in a Neurodegenerative Disease: the Cause for Absent EAAT2, a Glutamate Transporter, in Amyotrophic Lateral Sclerosis

1998 • 663 citations

Schizophrenia and cognitive dysmetria: a positron-emission tomography study of dysfunctional prefrontal-thalamic-cerebellar circuitry.

1996 • 618 citations

NMDA receptors activate the arachidonic acid cascade system in striatal neurons

1988 • 600 citations

Pronounced Reduction of Total Neuron Number in Mediodorsal Thalamic Nucleus and Nucleus Accumbens in Schizophrenics

1990 • 558 citations

Glutamate Transporter Protein Subtypes Are Expressed Differentially during Rat CNS Development

1997 • 553 citations

Cloning and Functional Characterization of a System ASC-like Na+-dependent Neutral Amino Acid Transporter

1996 • 506 citations

Ketamine activates psychosis and alters limbic blood flow in schizophrenia

1995 • 438 citations

Motor discoordination and increased susceptibility to cerebellar injury in GLAST mutant mice

1998 • 406 citations

Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family

1993 • 387 citations

Cytokine Effects on Glutamate Uptake by Human Astrocytes

2000 • 365 citations

PET and MRI of the thalamus in never-medicated patients with schizophrenia

1996 • 319 citations

Excitatory amino acid receptors, neural membrane phospholipid metabolism and neurological disorders

1991 • 286 citations

Reduced number of mediodorsal and anterior thalamic neurons in schizophrenia

2000 • 279 citations

MODEL PSYCHOSES AND SCHIZOPHRENIA

1962 • 269 citations

Review Article The family of sodium-dependent glutamate transporters: a focus on the GLT-1/EAAT2 subtype

1998 • 239 citations

Changes of NMDA Receptor Subunit (NR1, NR2B) and Glutamate Transporter (GLT1) mRNA Expression in Huntingtonʼs Disease—An In Situ Hybridization Study

1997 • 227 citations

Ionotropic Glutamate Receptor Binding and Subunit mRNA Expression in Thalamic Nuclei in Schizophrenia

2000 • 227 citations

The high-affinity glutamate transporters GLT1, GLAST, and EAAT4 are regulated via different signalling mechanisms

2000 • 216 citations

Positron Emission Tomography Studies of Abnormal Glucose Metabolism in Schizophrenia

1998 • 209 citations

Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia

1998 • 209 citations

The volume of the mediodorsal thalamic nucleus in treated and untreated schizophrenics

1992 • 202 citations

Three-Dimensional Analysis With MRI and PET of the Size, Shape, and Function of the Thalamus in the Schizophrenia Spectrum

1999 • 201 citations

Glutamate uptake is inhibited by arachidonic acid and oxygen radicals via two distinct and additive mechanisms.

1994 • 174 citations

N‐Methyl‐d‐Aspartate‐Sensitive Glutamate Receptors Induce Calcium‐Mediated Arachidonic Acid Release in Primary Cultures of Cerebellar Granule Cells

1990 • 171 citations

Volumetric Evaluation of the Thalamus in Schizophrenic Male Patients Using Magnetic Resonance Imaging

1998 • 168 citations

Expression Patterns and Regulation of Glutamate Transporters in the Developing and Adult Nervous System

1999 • 162 citations

Partial Volume Decrease of the Thalamus in Relatives of Patients With Schizophrenia

1998 • 159 citations

Effect of Phencyclidine in Chronic Schizophrenics

1967 • 154 citations

Distribution of Glutamate Transporter Subtypes During Human Brain Development

1997 • 152 citations

Lithium acutely inhibits and chronically up-regulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex

1998 • 149 citations

EAAT4 is a post-synaptic glutamate transporter at Purkinje cell synapses

1996 • 142 citations

Activation of N-methyl-D-aspartate-sensitive glutamate receptors stimulates arachidonic acid release in primary cultures of cerebellar granule cells

1988 • 137 citations

Phencyclidine selectively blocks a spinal action of N-methyl-d-aspartate in mice

1986 • 130 citations

The expression of the glial glutamate transporter protein EAAT2 in motor neuron disease: an immunohistochemical study

1998 • 130 citations

The RNA of the glutamate transporter EAAT2 is variably spliced in amyotrophic lateral sclerosis and normal individuals

1999 • 128 citations

Expression of the glial glutamate transporter EAAT2 in the human CNS: an immunohistochemical study

1997 • 116 citations

A Reentrant Loop Domain in the Glutamate Carrier EAAT1 Participates in Substrate Binding and Translocation

1998 • 111 citations

Correspondence

1997 • 110 citations

High-resolution SPECT study of regional cerebral blood flow in drug- free and drug-naive schizophrenic patients

1995 • 106 citations

Amphetamine increases the extracellular concentration of glutamate in striatum of the awake rat: involvement of high affinity transporter mechanisms

1999 • 82 citations

Metabotropic glutamate receptor mRNA expression in the schizophrenic thalamus

2000 • 74 citations

Chronic neuroleptic treatment alters expression of glial glutamate transporter GLT-1 mRNA in the striatum

1998 • 56 citations

NMDA Receptor-Mediated Arachidonic Acid Release In Neurons: Role In Signal Transduction and Pathological Aspects

1992 • 56 citations

The thalamus and the schizophrenia phenotype: failure to replicate reduced volume

1999 • 46 citations

The EAAT2 (GLT-1) gene in motor neuron disease: absence of mutations in amyotrophic lateral sclerosis and a point mutation in patients with hereditary spastic paraplegia

1998 • 40 citations

Wnt Signaling Induces GLT‐1 Expression in Rat C6 Glioma Cells

1999 • 36 citations

Chronic haloperidol treatment impairs glutamate transport in the rat striatum

1999 • 35 citations

Reversible activation of glutamate transport in rat brain glia by protein kinase C and an okadaic acid-sensitive phosphoprotein phosphatase.

1999 • 31 citations

Inducible expression and pharmacology of the human excitatory amino acid transporter 2 subtype of L‐glutamate transporter

1999 • 28 citations

Glycine site antagonists and partial agonists inhibit N-methyl-D-aspartate receptor-mediated [3H]arachidonic acid release in cerebellar granule cells.

1998 • 28 citations

Changes in expression and distribution of the glutamate transporter EAAT4 in developing mouse Purkinje cells

1997 • 27 citations

ARACHIDONIC ACID INHIBITS3H-GLUTAMATE UPTAKE WITH DIFFERENT POTENCIES IN RODENT CENTRAL NERVOUS SYSTEM REGIONS EXPRESSING DIFFERENT TRANSPORTER SUBTYPES

1997 • 26 citations

Venom phospholipase A2-induced impairment of glutamate uptake: An indirect and nonselective effect related to phospholipid hydrolysis

1998 • 12 citations