Crim1^{KST264/KST264} mice display a disruption of the Crim1 gene resulting in perinatal lethality with defects in multiple organ systems

A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye.

1995 • 1,118 citations

BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning.

1995 • 1,021 citations

Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis

1996 • 708 citations

Absence of integrin α6 leads to epidermolysis bullosa and neonatal death in mice

1996 • 539 citations

Roles for Laminin in Embryogenesis: Exencephaly, Syndactyly, and Placentopathy in Mice Lacking the Laminin α5 Chain

1998 • 484 citations

α3β1 Integrin Is Required for Normal Development of the Epidermal Basement Membrane

1997 • 407 citations

Defining brain wiring patterns and mechanisms through gene trapping in mice

2001 • 391 citations

Integrin β4 mutations associated with junctional epidermolysis bullosa with pyloric atresia

1995 • 389 citations

Conditional Ablation of β1 Integrin in Skin

2000 • 376 citations

Capturing genes encoding membrane and secreted proteins important for mouse development.

1995 • 321 citations

Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1/Fras1 encoding a putative extracellular matrix protein

2003 • 250 citations

BMP-binding modules in chordin: a model for signalling regulation in the extracellular space

2000 • 244 citations

Synergistic activities of α3 and α6 integrins are required during apical ectodermal ridge formation and organogenesis in the mouse

1999 • 233 citations

BMP7 Null Mutation in Mice: Developmental Defects in Skeleton, Kidney, and Eye

1997 • 230 citations

Chordin-like CR domains and the regulation of evolutionarily conserved extracellular signaling systems

2002 • 172 citations

Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs

2005 • 157 citations

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1

2004 • 142 citations

Mice Null for Sox18 Are Viable and Display a Mild Coat Defect

2000 • 114 citations

The extracellular matrix geneFrem1is essential for the normal adhesion of the embryonic epidermis

2004 • 112 citations

Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice

2003 • 111 citations

CRIM1, a novel gene encoding a cysteine-rich repeat protein, is developmentally regulated and implicated in vertebrate CNS development and organogenesis

2000 • 99 citations

CRIM1 Regulates the Rate of Processing and Delivery of Bone Morphogenetic Proteins to the Cell Surface

2003 • 98 citations

Histochemical Staining Following LacZ Gene Transfer Underestimates Transfection Efficiency

1997 • 91 citations

Junctional Epidermolysis Bullosis: Defects in Expression of Epiligrin/Nicein/Kalinin and Integrin ß4 That Inhibit Hemidesmosome Formation

1994 • 84 citations

The genetics of Fraser syndrome and the blebs mouse mutants

2005 • 82 citations

Contributions by members of the TGFbeta superfamily to lens development

2004 • 65 citations

BMP 7 Is Required for Nephrogenesis, Eye Development, and Skeletal Patterninga

1996 • 55 citations

CRIM1 is involved in endothelial cell capillary formation in vitro and is expressed in blood vessels in vivo

2002 • 44 citations

Knockdown of zebrafish crim1 results in a bent tail phenotype with defects in somite and vascular development

2006 • 25 citations

Expression of Crim1 during murine ocular development

2000 • 23 citations

Characterisation ofCrim1 expression in the developing mouse urogenital tract reveals a sexually dimorphic gonadal expression pattern

2000 • 22 citations