Persistent phosphorylation of cyclic amp responsive element-binding protein and activating transcription factor-2 transcription factors following transient cerebral ischemia in rat brain

Delayed neuronal death in the gerbil hippocampus following ischemia

1982 • 2,856 citations

Temporal profile of neuronal damage in a model of transient forebrain ischemia

1982 • 2,695 citations

The regulation and function of c-fos and other immediate early genes in the nervous system

1990 • 2,392 citations

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein

1994 • 1,802 citations

The regulation of transcription by phosphorylation

1992 • 1,316 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites

1995 • 1,181 citations

CREB Phosphorylation and Dephosphorylation: A Ca2+- and Stimulus Duration–Dependent Switch for Hippocampal Gene Expression

1996 • 1,109 citations

Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila

1994 • 959 citations

Genetic dissection of consolidated memory in Drosophila

1994 • 901 citations

Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation

1990 • 741 citations

Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model

1984 • 741 citations

Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB

1994 • 732 citations

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

1994 • 730 citations

CREB as a Memory Modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in drosophila

1995 • 639 citations

cAMP response element-binding protein is activated by Ca2+/calmodulin- as well as cAMP-dependent protein kinase.

1991 • 552 citations

Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma.

1992 • 521 citations

ATF-2 contains a phosphorylation-dependent transcriptional activation domain.

1995 • 504 citations

Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements

1993 • 440 citations

Historical Overview

1988 • 428 citations

Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors

1994 • 404 citations

CREB: A mediator of long-term memory from mollusks to mammals

1994 • 371 citations

Ubiquitin C-Terminal Hydrolase Is an Immediate-Early Gene Essential for Long-Term Facilitation in Aplysia

1997 • 359 citations

Thresholds for synaptic activation of transcription factors in hippocampus: correlation with long-term enhancement

1993 • 345 citations

Increased production of the TrkB protein tyrosine kinase receptor after brain insults

1993 • 344 citations

The CREB family of transcription activators

1992 • 298 citations

Morphological plasticity of dendritic spines in central neurons is mediated by activation of cAMP response element binding protein

1997 • 292 citations

Proto-oncogene transcription factors and epilepsy

1991 • 252 citations

Is c-Jun involved in nerve cell death following status epilepticus and hypoxic-ischaemic brain injury?

1993 • 215 citations

Phosphorylation of Transcription Factor CREB in Rat Spinal Cord after Formalin-Induced Hyperalgesia: Relationship toc-fosInduction

1997 • 213 citations

A role for immediate-early transcription factors in learning and memory

1996 • 187 citations

In situ hybridization analysis of c-fos and c-jun expression in the rat brain following transient forebrain ischemia

1991 • 180 citations

Long-lasting expression of JUN and KROX transcription factors and nitric oxide synthase in intrinsic neurons of the rat brain following axotomy

1993 • 171 citations

Differential Transcription and Translation of Immediate Early Genes in the Gerbil Hippocampus after Transient Global Ischemia

1993 • 156 citations

Tyrosine Phosphorylation and Activation of Mitogen‐ Activated Protein Kinase in the Rat Brain Following Transient Cerebral Ischemia

1994 • 147 citations

Continuous lidocaine infusion and focal feline cerebral ischemia.

1990 • 140 citations

Activating transcription factor-1 can mediate Ca(2+)- and cAMP-inducible transcriptional activation.

1993 • 137 citations

Differential Expression of the Immediate Early Genes c-Fos, c-Jun, JunB, andNGFI-B in the Rat Brain following Transient Forebrain Ischemia

1994 • 128 citations

Ischemia and Reperfusion Enhance ATF-2 and c-Jun Binding to cAMP Response Elements and to an AP-1 Binding Site from the c-jun Promoter

1995 • 118 citations

70-kDa heat shock protein and c-fos gene expression after transient ischemia.

1990 • 116 citations

Regulation of c-jun Expression during Hypoxic and Low-Glucose Stress

1994 • 104 citations

Impairment of protein ubiquitination may cause delayed neuronal death

1989 • 96 citations

cAMP and tumor necrosis factor competitively regulate transcriptional activation through and nuclear factor binding to the cAMP-responsive element/activating transcription factor element of the endothelial leukocyte adhesion molecule-1 (E-selectin) promoter.

1994 • 79 citations

Regulation of c-jun expression during hypoxic and low-glucose stress.

1994 • 79 citations

Biphasic Expression of the Fos and Jun Families of Transcription Factors Following Transient Forebrain Ischaemia in the Rat. Effect of Hypothermia

1995 • 77 citations

Persistent Translocation of Ca²⁺/Calmodulin‐Dependent Protein Kinase II to Synaptic Junctions in the Vulnerable Hippocampal CA1 Region Following Transient Ischemia

1995 • 63 citations

Nitric oxide induces c-fos gene expression via cyclic AMP response element binding protein (CREB) phosphorylation in rat retinal pigment epithelium

1995 • 53 citations

Alterations of Ca2+/calmodulin-dependent protein kinase II and its messenger RNA in the rat hippocampus following normo- and hypothermic ischemia

1995 • 52 citations

Transient Ischemia Depletes Free Ubiquitin in the Gerbil Hippocampal CA1 Neurons

1997 • 51 citations

Prolonged expression of c-jun and associated activity of the transcription factor AP-1, during apoptosis in a human leukaemic cell line.

1994 • 49 citations

Light‐Induced CREB Phosphorylation and Gene Expression in Rat Retinal Cells

1995 • 43 citations

Both ATF-2 and c-Jun are Phosphorylated by Stress-Activated Protein Kinases in Response to UV Irradiation

1995 • 40 citations

Calcium Antagonists: Pharmacology and Clinical Research

1988 • 32 citations

The Phosphorylation State of the cAMP Response Element Binding Protein Is Decreased in Diabetic Rat Liver

1995 • 12 citations

Activation of the ATP.Mg-dependent type 1 protein phosphatase by the Fe2+/ascorbate system

1996 • 6 citations

CREB: A Mediator of Long-Term Memory from Mollusks to Mammals Minireview

1994 • 2 citations