A homology model of the Id-3 helix-loop-helix domain as a basis for structure-function predictions

<scp>CHARMM</scp>: A program for macromolecular energy, minimization, and dynamics calculations

1983 • 14,615 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Multiple sequence alignment with hierarchical clustering

1988 • 5,250 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

The protein Id: A negative regulator of helix-loop-helix DNA binding proteins

1990 • 2,273 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

Max: A Helix-Loop-Helix Zipper Protein That Forms a Sequence-Specific DNA-Binding Complex with Myc

1991 • 1,650 citations

Influence of proline residues on protein conformation

1991 • 1,125 citations

Differences and Similarities in DNA-Binding Preferences of MyoD and E2A Protein Complexes Revealed by Binding Site Selection

1990 • 957 citations

The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation

1990 • 794 citations

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

1993 • 723 citations

Do salt bridges stabilize proteins? A continuum electrostatic analysis

1994 • 629 citations

Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins.

1991 • 601 citations

Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

1991 • 541 citations

Two Distinct Transcription Factors that Bind the Immunoglobulin Enhancer μE5/κE2 Motif

1990 • 478 citations

Crystal structure of MyoD bHLH domain-DNA complex: Perspectives on DNA recognition and implications for transcriptional activation

1994 • 448 citations

Crystal structure of transcription factor E47: E-box recognition by a basic region helix-loop-helix dimer.

1994 • 420 citations

The Drosophila extramacrochaetae locus, an antagonist of proneural genes that, like these genes, encodes a helix-loop-helix protein

1990 • 387 citations

Reversal of Terminal Differentiation Mediated by p107 in Rb ^-/- Muscle Cells

1994 • 369 citations

Binding of chloromethyl ketone substrate analogs to crystalline papain

1976 • 352 citations

Differential expression of myogenic determination genes in muscle cells: possible autoactivation by the Myf gene products.

1989 • 349 citations

Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal

1994 • 348 citations

The expression pattern ofId4, a novel dominant negative helix-loop-helix protein, is distinct fromId1,1d2andId3

1994 • 274 citations

Regulation of G1 progression by E2A and Id helix-loop-helix proteins.

1994 • 199 citations

Structure of porphobilinogen deaminase reveals a flexible multidomain polymerase with a single catalytic site

1992 • 197 citations

Construction of validated, non-redundant composite protein sequence databases

1990 • 187 citations

Packing and hydrophobicity effects on protein folding and stability: Effects of β‐branched amino acids, valine and isoleucine, on the formation and stability of two‐stranded α‐helical coiled coils/leucine zippers

1993 • 173 citations

Mutually exclusive expression of a helix-loop-helix gene and N-myc in human neuroblastomas and in normal development.

1992 • 109 citations

An immediate early human gene encodes an Id-like helix-loop-helix protein and is regulated by protein kinase C activation in diverse cell types.

1993 • 98 citations

A cDNA from a mouse pancreatic β cell encoding a putative transcription factor of the insulin gene

1990 • 91 citations

The loop region of the helix-loop-helix protein Id1 is critical for its dominant negative activity.

1993 • 91 citations

Construction, purification, and characterization of a hybrid protein comprising the DNA binding domain of the LexA repressor and the Jun leucine zipper: a circular dichroism and mutagenesis study

1991 • 58 citations

Dimerization specificity of myogenic helix-loop-helix DNA-binding factors directed by nonconserved hydrophilic residues.

1993 • 54 citations

Co-operativity of functional domains in the muscle-specific transcription factor Myf-5.

1992 • 48 citations

Posttranscriptional regulation of Id1 activity in cardiac muscle. Alternative splicing of novel Id1 transcript permits homodimerization.

1994 • 45 citations

Built by association: structure and function of helix-loop-helix DNA-binding proteins

1994 • 39 citations

Nucleotide sequence of the cDNA encoding human helix-loop-helix Id-1 protein: Identification of functionally conserved residues common to Id proteins

1994 • 29 citations

A B cell specific immediate early human gene is located on chromosome band 1q31 and encodes an α helical basic phosphoprotein

1993 • 27 citations