The loop region of the helix-loop-helix protein Id1 is critical for its dominant negative activity.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

The protein Id: A negative regulator of helix-loop-helix DNA binding proteins

1990 • 2,273 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

The myoD Gene Family: Nodal Point During Specification of the Muscle Cell Lineage

1991 • 1,564 citations

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.

1992 • 1,156 citations

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

1988 • 1,084 citations

Differences and Similarities in DNA-Binding Preferences of MyoD and E2A Protein Complexes Revealed by Binding Site Selection

1990 • 957 citations

Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo

1991 • 874 citations

The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation

1990 • 794 citations

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

1993 • 723 citations

Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins.

1991 • 601 citations

Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins.

1992 • 480 citations

The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1—Pit-1 interactions

1990 • 403 citations

An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene.

1991 • 352 citations

Mutations that disrupt DNA binding and dimer formation in the E47 helix-loop-helix protein map to distinct domains.

1990 • 316 citations

Inhibition of Myeloid Differentiation by the Helix-Loop-Helix Protein Id

1992 • 267 citations

I-POU: a POU-domain protein that inhibits neuron-specific gene activation

1991 • 217 citations

A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines.

1993 • 173 citations

Repression of immunoglobulin enhancers by the helix-loop-helix protein Id: implications for B-lymphoid-cell development.

1991 • 151 citations

Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins.

1991 • 150 citations

Functional characterization of the developmentally controlled immunoglobulin kappa 3' enhancer: regulation by Id, a repressor of helix-loop-helix transcription factors.

1991 • 123 citations

The protein Id: a negative regulator of helix-loop-helix DNA binding proteins

1990 • 123 citations

Expression of helix-loop-helix regulatory genes during differentiation of mouse osteoblastic cells

1992 • 107 citations

Multiple oligomeric states regulate the DNA binding of helix-loop-helix peptides.

1993 • 103 citations

Myocardial activation of the human cardiac alpha-actin promoter by helix-loop-helix proteins.

1992 • 96 citations

A Heterodimer of HEB and an E12-Related Protein Interacts with the CD4 Enhancer and Regulates Its Activity in T-Cell Lines

1993 • 71 citations

Molecular model for DNA recognition by the family of basic-helix-loop-helix-zipper proteins.

1992 • 43 citations

Repression of Immunoglobulin Enhancers by the Helix-Loop-Helix Protein Id: Implications for B-Lymphoid-Cell Development

1991 • 43 citations

Functional Characterization of the Developmentally Controlled Immunoglobulin Kappa 3′ Enhancer: Regulation by Id, a Repressor of Helix-Loop-Helix Transcription Factors

1991 • 40 citations