Therapeutic Drug Monitoring in Pregnancy

Oxford reviews of reproductive biology

1981 • 752 citations

Human Saliva: Clinical Chemistry and Microbiology

2021 • 380 citations

Valproic acid

1987 • 290 citations

Frontiers in Biochemical and Pharmacological Research in Depression

1984 • 278 citations

Clinical Pharmacokinetics of Digoxin

1977 • 255 citations

Anticonvulsants during Pregnancy and Lactation

1982 • 165 citations

Valproic acid dosage and plasma protein binding and clearance

1980 • 148 citations

Renal physiology in pregnancy

1979 • 142 citations

Epilepsy, pregnancy, and the child

1982 • 140 citations

Therapeutic drug monitoring of tricyclic antidepressants.

1988 • 138 citations

Evaluation of valproic acid (VPA) developmental toxicity and pharmacokinetics in Sprague-Dawley rats

1988 • 136 citations

Cyclosporine Monitoring in Renal Transplantation

1989 • 130 citations

Plasma Protein Binding of Drugs in Pregnancy and in Neonates

1990 • 127 citations

Changes in serum albumin and α₁‐acid glycoprotein concentrations during pregnancy: an analysis of fetal‐maternal pairs

1984 • 114 citations

Pharmacokinetics and Safety of Antimicrobial Agents During Pregnancy

1985 • 112 citations

Lithium and Pregnancy--II, Hazards to Women Given Lithium During Pregnancy and Delivery

1973 • 109 citations

Clinical Pharmacology of the Perinatal Period and Early Infancy

1989 • 109 citations

Therapeutic drug monitoring

1988 • 106 citations

Clinical Pharmacokinetics of Digoxin 1980

1980 • 98 citations

Pharmacokinetics in pregnancy and placental drug transfer.

1989 • 92 citations

SALIVARY PHENYTOIN CONCENTRATIONS IN EPILEPSY AND IN CHRONIC RENAL FAILURE

1976 • 83 citations

Drug Kinetics and Hepatic Blood Flow

1979 • 76 citations

Ethosuximide in epileptic women during pregnancy and lactation period. Placental transfer, serum concentrations in nursed infants and clinical status.

1984 • 71 citations

Pharmacokinetic Drug Data1

1988 • 70 citations

Effects of Development, Aging, and Renal and Hepatic Insufficiency as well as Hemodialysis on the Plasma Concentrations of Albumin and α1-Acid Glycoprotein

1986 • 67 citations

Effect of protein binding on serum bactericidal activities of ceftazidime and cefoperazone in healthy volunteers

1988 • 66 citations

Serum protein binding and free concentration of phenytoin and phenobarbitone in pregnancy.

1982 • 66 citations

Plasma concentrations of unbound phenytoin in the management of epilepsy.

1984 • 58 citations

Carbamazepine Protein Binding and Disposition in Pregnancy

1985 • 56 citations

Carbamazepine and carbamazepine-10,11- epoxide during pregnancy and postnatal period in epileptic mother and their nursed infants: pharmacokinetics and clinical effects.

1983 • 54 citations

Prophylactic Lithium in Postpartum Affective Psychosis

1988 • 53 citations

Pharmacokinetic factors affecting antidepressant drug clearance and clinical effect: evaluation of doxepin and imipramine--new data and review.

1988 • 52 citations

Effect of sodium valproate on plasma protein binding of diphenylhydantoin.

1977 • 49 citations

Theophylline clearance during pregnancy.

1986 • 45 citations

Phenytoin-valproate interaction: importance of saliva monitoring in epilepsy.

1982 • 41 citations

Antipyretic analgesics in patients on antiepileptic drug therapy

1979 • 40 citations

Plasma protein binding of phenytoin in the aged: in vivo studies.

1982 • 38 citations

Effect of Antacids on Phenytoin Bioavailability

1981 • 37 citations

Variations in Gentamicin C1, C1a, C2, and C2a Content of Some Preparations of Gentamicin Sulphate Used Clinically as Determined by High-Performance Liquid Chromatography

1983 • 36 citations

New Drugs: Practical clinical pharmacology: monitoring drug concentrations and clinical trials

1988 • 35 citations

Polyhydramnios with maternal lithium treatment.

1990 • 35 citations

Cefazolin serum protein binding and its inhibition by bilirubin, fatty acids and other drugs

1988 • 35 citations

Phenytoin kinetics during pregnancy and the puerperium

1986 • 34 citations

Clinical Pharmacokinetics in Pregnancy and Perinatology

1987 • 34 citations

Protein Binding of Antiepileptic Drugs During Pregnancy, Labor, and Puerperium

1990 • 33 citations

Clinical pharmacology of antidepressant drugs: pharmacogenetics.

1984 • 33 citations

Basic Pharmacokinetics

1986 • 31 citations

Drug Pharmacokinetics in the Postoperative Period

1979 • 30 citations

Do saliva concentrations predict plasma unbound theophylline concentrations? A problem re‐examined.

1984 • 29 citations

Serum Lithium Monitoring of Prophylactic Treatment

1988 • 29 citations

Behavioral and Cognitive Toxicity Related to Elevated Plasma Tricyclic Antidepressant Levels

1988 • 29 citations

Compliance during tricyclic antidepressant therapy: pharmacokinetic and analytical issues.

1988 • 26 citations

Alteration of methyldopa absorption, metabolism, and blood pressure control caused by ferrous sulfate and ferrous gluconate

1988 • 26 citations

Characterization of theophylline binding to serum proteins in pregnant and nonpregnant women

1990 • 24 citations

Determination of Unbound Valproic Acid Concentration in Plasma by Equilibrium Dialysis and Gas—Liquid Chromatography

1982 • 24 citations

Active metabolites of antidepressants: pharmacodynamics and relevant pharmacokinetics.

1984 • 23 citations

Phenytoin pharmacokinetics in burned rats and plasma protein binding of phenytoin in burned patients.

1980 • 22 citations

Serum protein binding of diazepam, desmethyldiazepam, furosemide, indomethacin, warfarin, and phenobarbital in human fetus, mother, and newborn infant.

1983 • 19 citations

Effect of a protein binding change on unbound and total plasma concentrations for drugs of intermediate hepatic extraction

1988 • 19 citations

PLASMA CONCENTRATIONS OF UNBOUND VALPROATE AND THE MANAGEMENT OF EPILEPSY

1987 • 17 citations

Serum protein binding of diazepam and propranolol in the feto-maternal unit from early to late pregnancy.

1986 • 17 citations

Plasma level monitoring of antidepressants: theoretical basis and clinical application.

1984 • 16 citations

The Role of the Placenta in Developmental Toxicology

1982 • 16 citations

Endogenous Digoxin-Like Substance(s) Associated with Uneventful and High-Risk Pregnancies

1988 • 15 citations

Unbound phenytoin plasma concentrations in patients comedicated with sodium valproate‐the predictive value of plasma albumin concentration.

1989 • 14 citations

Differential transplacental binding of valproic acid: influence of free fatty acids.

1984 • 14 citations

Gentamicin serum half-life: a comparison between pregnant and non-pregnant women

1985 • 14 citations

Plasma protein binding of disopyramide in pregnant and postpartum women, and in neonates and their mothers.

1990 • 12 citations

The impact of neglecting nonlinear plasma-protein binding on disopyramide bioavailability studies

1986 • 9 citations

Interaction of Microbiology and Pharmacokinetics in the Selection of Appropriate Antibiotic Therapy

1989 • 6 citations

Pregnancy-Specific Changes of Antipyrine Pharmacokinetics Correlate Inversely with Changes of Estradiol/Progesterone Plasma Concentration Ratios

1988 • 5 citations

Pharmacokinetics of Pivmecillinam Hydrochloride in Pregnant and Non‐pregnant Women

1986 • 4 citations

In vitro protein binding interaction studies involving cefixime

1988 • 4 citations