Phenytoin kinetics during pregnancy and the puerperium

physiology of human pregnancy

1971 • 621 citations

Binding of Drugs to Serum Albumin

1976 • 410 citations

Plasma protein binding of diphenylhydantoin in man; Interaction with other drugs and the effect of temperature and plasma dilution

1970 • 243 citations

The Distribution and Excretion of Phenobarbital1

1957 • 225 citations

Diphenylhydantoin: Placental transport, fetallocalization, neonatal metabolism, and possible teratogenic effects

1971 • 164 citations

Plasma protein binding of diphenylhydantoin Effects of sex hormones, renal and hepatic disease

1974 • 159 citations

Displacement of One Drug by Another from Carrier or Receptor Sites

1965 • 152 citations

Drug disposition and pharmacokinetics in the maternal-placental-fetal unit

1980 • 134 citations

Plasma Protein Binding of Drugs in Pregnancy

1982 • 128 citations

Antiepileptic Drugs

1979 • 127 citations

Plasma anticonvulsant concentrations during pregnancy

1977 • 98 citations

Plasma Drug Level Monitoring in Pregnancy

1977 • 91 citations

PHENYTOIN and PHENOBARBITONE PLASMA CLEARANCE DURING PREGNANCY

1976 • 89 citations

SALIVARY PHENYTOIN CONCENTRATIONS IN EPILEPSY AND IN CHRONIC RENAL FAILURE

1976 • 83 citations

Drug Protein Binding and the Nephrotic Syndrome

1976 • 78 citations

Plasma nonesterified fatty acids in normal pregnancy and the puerperium.

1960 • 68 citations

Serum protein binding and free concentration of phenytoin and phenobarbitone in pregnancy.

1982 • 66 citations

Status epilepticus in pregnancy

1978 • 64 citations

Plasma protein binding interaction between phenytoin and valproic acid in vitro.

1978 • 62 citations

The influence of normal pregnancy and the postpartum state on plasma proteins and lipids

1963 • 62 citations

Plasma concentrations of unbound phenytoin in the management of epilepsy.

1984 • 58 citations

The Place of Saliva in Antiepileptic Drug Monitoring

1984 • 57 citations

Plasma protein binding of phenytoin in health and disease: relevance to therapeutic drug monitoring.

1980 • 55 citations

Effects of Age, Sex, Obesity, and Pregnancy on Plasma Diphenylhydantoin Levels

1974 • 47 citations

Phenytoin-valproate interaction: importance of saliva monitoring in epilepsy.

1982 • 41 citations

Serum protein binding of drugs during and after pregnancy in rats.

1980 • 39 citations

METABOLISM OF DIPHENYLHYDANTOIN (PHENYTOIN) DURING PREGNANCY

1979 • 38 citations

Effect of Antacids on Phenytoin Bioavailability

1981 • 37 citations

Plasma Protein Binding of Phenytoin in Health and Disease

1980 • 36 citations

Effects of hormonal contraceptives and pregnancy on serum protein pattern

1973 • 35 citations

Mechanism of Altered Drug Binding to Serum Proteins in Pregnant Women

1984 • 31 citations

Effect of renal transplantation on protein binding of drugs in serum of donor and recipient

1976 • 24 citations

Therapeutic Drug Monitoring

1980 • 20 citations

Interpretation of Drug Levels: Relevance of Plasma Protein Binding

1980 • 14 citations

Passage of diphenylhydantoin across the placenta

1970 • 7 citations

Metabolism in vitro of 5,5-diphenylhydantoin

1972 • 6 citations