Effect of protein binding on serum bactericidal activities of ceftazidime and cefoperazone in healthy volunteers

Postantibiotic Suppression of Bacterial Growth

1981 • 311 citations

New In Vitro Model to Study the Effect of Antibiotic Concentration and Rate of Elimination on Antibacterial Activity

1978 • 183 citations

Protein Binding of Antimicrobials

1977 • 162 citations

THE BINDING OF ANTIBIOTICS TO SERUM PROTEINS

1965 • 156 citations

Effect of protein binding on antibiotic activity in vivo

1983 • 151 citations

The Influence of Protein Binding upon Tissue Fluid Levels of Six -Lactam Antibiotics

1980 • 148 citations

INFLUENCE OF BINDING ON THE PHARMACOLOGIC ACTIVITY OF ANTIBIOTICS

1973 • 145 citations

Simultaneous antibiotic levels in “breakthrough” gram-negative rod bacteremia

1976 • 135 citations

Protein binding of β-lactams: the effects on activity and pharmacology particularly tissue penetration. I

1983 • 130 citations

In Vitro Veritas? Antimicrobial Susceptibility Tests and Their Clinical Relevance

1981 • 122 citations

The Relation of Protein Binding to the Pharmacology and Antibacterial Activity of Penicillins X, G, Dihydro F, and K

1947 • 108 citations

A Method for Measurement of Antibiotics in Human Interstitial Fluid

1972 • 92 citations

Failure of a Once-Daily Regimen of Cefonicid for Treatment of Endocarditis Due to Staphylococcus aureus

1984 • 71 citations

Effect of protein binding on levels of ampicillin and cloxacillin in synovial fluid

1972 • 62 citations

Cloxacillin and Nafcillin: Serum Binding and Its Relationship to Antibacterial Effect in Mice

1973 • 61 citations

Analysis of a new method for assessing activity of combinations of antimicrobials: area under the bactericidal activity curve

1985 • 57 citations

Cephalosporin Antibiotics in Therapy of Experimental Streptococcus pneumoniae and Haemophilus influenzae Meningitis in Rabbits

1978 • 54 citations

Protein binding of β-lactams: the effects on activity and pharmacology particularly tissue penetration. II

1983 • 53 citations

Prediction of Cefazolin Penetration into High- and Low-Protein-Containing Extravascular Fluid: New Method for Performing Simultaneous Studies

1978 • 47 citations

Relevance of serum protein binding of cefoxitin and cefazolin to their activities against Klebsiella pneumoniae pneumonia in rats

1985 • 33 citations

Effect of method of administration on extravascular penetration of four antibiotics

1982 • 26 citations

Anomalous Effect of Serum on the Antimicrobial Activity of Cefoperazone

1981 • 14 citations

Effect of dose on pharmacokinetics and serum bactericidal activity of mezlocillin

1987 • 12 citations

Comparative Studies of the Activity of Ciclacillin and Dicloxacillin

1976 • 7 citations

Serum bactericidal activity of cefoperazone and ceftazidime at increasing dosages against Pseudomonas aeruginosa

1983 • 6 citations