Endogenous presenilin 1 redistributes to the surface of lamellipodia upon adhesion of Jurkat cells to a collagen matrix

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1995 • 3,985 citations

Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus

1995 • 2,548 citations

CD44 is the principal cell surface receptor for hyaluronate

1990 • 2,433 citations

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1995 • 2,028 citations

CD44 and Its Interaction with Extracellular Matrix

1993 • 1,082 citations

Skeletal and CNS Defects in Presenilin-1-Deficient Mice

1997 • 953 citations

Presenilin 1 is required for Notch 1 and Dll1 expression in the paraxial mesoderm

1997 • 721 citations

Alzheimer–associated presenilins 1 and 2 : Neuronal expression in brain and localization to intracellular membranes in mammalian cells

1996 • 549 citations

Mechanisms and Molecules that Control Growth Cone Guidance

1996 • 515 citations

Interfering with Apoptosis: Ca ²⁺ -Binding Protein ALG-2 and Alzheimer's Disease Gene ALG-3

1996 • 481 citations

The Ins and Outs of Notch Signaling

1997 • 386 citations

Protein Topology of Presenilin 1

1996 • 374 citations

The presenilins and Alzheimer's disease

1997 • 364 citations

Assessment of normal and mutant human presenilin function in Caenorhabditis elegans

1996 • 360 citations

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

1997 • 299 citations

Limited T-cell receptor beta-chain heterogeneity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis.

1991 • 297 citations

Expression of Presenilin 1 and 2 (PS1 and PS2) in Human and Murine Tissues

1996 • 290 citations

Integrin-mediated short-term memory in Drosophila

1998 • 283 citations

Mutations of the presenilin I gene in families with early-onset Alzheimer's disease

1995 • 270 citations

Direct interaction of filamin (ABP-280) with the beta 2-integrin subunit CD18.

1995 • 252 citations

Interaction between amyloid precursor protein and presenilins in mammalian cells: Implications for the pathogenesis of Alzheimer disease

1997 • 237 citations

Alzheimer Presenilins in the Nuclear Membrane, Interphase Kinetochores, and Centrosomes Suggest a Role in Chromosome Segregation

1997 • 219 citations

Formation of stable complexes between two Alzheimer's disease gene products: Presenilin-2 and β-amyloid precursor protein

1997 • 216 citations

Membrane Topology of the C. elegans SEL-12 Presenilin

1996 • 204 citations

Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites.

1996 • 203 citations

Presenilins and Alzheimer disease

1995 • 193 citations

Light and Electron Microscopic Localization of Presenilin-1 in Primate Brain

1997 • 166 citations

Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus.

1995 • 165 citations

ICAMs Redistributed by Chemokines to Cellular Uropods as a Mechanism for Recruitment of T Lymphocytes

1997 • 136 citations

Actin crosslinking proteins at the leading edge

1994 • 128 citations

A One-Step Procedure for Biotinylation and Chemical Cross-Linking of Lymphocyte Surface and Intracellular Membrane-Associated Molecules

1995 • 126 citations

Interaction of Presenilins with the Filamin Family of Actin-Binding Proteins

1998 • 125 citations

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

1997 • 96 citations

Identification and neuron specific expression of the S182/presenilin I protein in human and rodent brains

1996 • 91 citations

Neuronal Localization of Presenilin-1 and Association with Amyloid Plaques and Neurofibrillary Tangles in Alzheimer’s Disease

1997 • 89 citations

Progress in Alzheimer’s and Parkinson’s Diseases

1998 • 82 citations

The Functional Expression of Sodium-dependent Bile Acid Transport in Madin-Darby Canine Kidney Cells Transfected with the cDNA for Microsomal Epoxide Hydrolase

1996 • 81 citations

Book Reviews Science and Dissent in Post-Mao China, reviewed by M. Goldman * Comparative Vertebrate Neuroanatomy, E. G. Jones * Particle Physics, P. Forman * Vignette * Browsings

1996 • 70 citations

Identification and neuron specific expression of the S182/presenilin I protein in human and rodent brains

1996 • 69 citations

Presence of functionally active cytochrome P-450IIE1 in the plasma membrane of rat hepatocytes

1992 • 69 citations

Cell surface expression of the Alzheimer disease-related presenilin proteins

1997 • 63 citations

Membrane proteins which exhibit multiple topological orientations.

1996 • 58 citations

Widespread neuronal expression of the presenilin-1 early-onset Alzheimer's disease gene in the murine brain.

1996 • 56 citations

Localization of Alzheimer-Associated Presenilin 1 in Transfected COS-7 Cells

1996 • 46 citations

Determinants of carboxyl-terminal domain translocation during prion protein biogenesis

1994 • 34 citations

Presenilin-1 Immunoreactivity Is Localized Intracellularly in Alzheimer's Disease Brain, but Not Detected in Amyloid Plaques

1997 • 27 citations

Specific transcellular binding between membrane proteins crucial to Alzheimer disease.

1996 • 27 citations

T-cell development: Is Notch a key player in lineage decisions?

1997 • 15 citations

Identification of Peptides Binding to Presenilin 1 by Screening of Random Peptide Display Libraries

1998 • 3 citations