Endothelial cells and VEGF in vascular development

RETRACTED ARTICLE: Pluripotency of mesenchymal stem cells derived from adult marrow

2002 • 5,594 citations

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1996 • 4,143 citations

Angiogenesis in health and disease

2003 • 4,127 citations

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1995 • 3,977 citations

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

2003 • 3,707 citations

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

1996 • 3,664 citations

Osteoblastic cells regulate the haematopoietic stem cell niche

2003 • 3,370 citations

SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells

2005 • 3,056 citations

Identification of the haematopoietic stem cell niche and control of the niche size

2003 • 2,900 citations

Circulating angiogenic factors and the risk of preeclampsia*

2004 • 2,591 citations

Latest Advances in Understanding Preeclampsia

2005 • 2,482 citations

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

1999 • 2,034 citations

Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4

1998 • 1,663 citations

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions

2001 • 1,640 citations

Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration

2003 • 1,598 citations

A common precursor for hematopoietic and endothelial cells

1998 • 1,433 citations

Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors

2000 • 1,372 citations

Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover

2002 • 1,342 citations

Placental development: Lessons from mouse mutants

2001 • 1,239 citations

Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

2003 • 1,216 citations

Optical Projection Tomography as a Tool for 3D Microscopy and Gene Expression Studies

2002 • 1,168 citations

Induction of Pancreatic Differentiation by Signals from Blood Vessels

2001 • 1,052 citations

Notch signaling is essential for vascular morphogenesis in mice

2000 • 1,042 citations

Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

1999 • 1,019 citations

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration

2001 • 1,012 citations

Common mechanisms of nerve and blood vessel wiring

2005 • 1,006 citations

A Requirement for Flk1 in Primitive and Definitive Hematopoiesis and Vasculogenesis

1997 • 938 citations

Notch signaling is required for arterial-venous differentiation during embryonic vascular development

2001 • 899 citations

Liver Organogenesis Promoted by Endothelial Cells Prior to Vascular Function

2001 • 857 citations

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

2003 • 758 citations

Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis

2003 • 755 citations

Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

2002 • 726 citations

Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets

1997 • 719 citations

Symmetrical Mutant Phenotypes of the Receptor EphB4 and Its Specific Transmembrane Ligand ephrin-B2 in Cardiovascular Development

1999 • 708 citations

VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism

2002 • 706 citations

Haemangioblast commitment is initiated in the primitive streak of the mouse embryo

2004 • 673 citations

Angiogenesis-Independent Endothelial Protection of Liver: Role of VEGFR-1

2003 • 658 citations

Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity

2005 • 629 citations

The Notch target genes Hey1 and Hey2 are required for embryonic vascular development

2004 • 629 citations

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development

2004 • 587 citations

Gridlock signalling pathway fashions the first embryonic artery

2001 • 552 citations

Dosage-sensitive requirement for mouse Dll4 in artery development

2004 • 546 citations

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

2004 • 516 citations

The meso-angioblast: a multipotent, self-renewing cell that originates from the dorsal aorta and differentiates into most mesodermal tissues

2002 • 507 citations

Angiogenic network formation in the developing vertebrate trunk

2003 • 505 citations

TGF-? receptor function in the endothelium

2004 • 502 citations

Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS

2004 • 494 citations

Flow regulates arterial-venous differentiation in the chick embryo yolk sac

2003 • 468 citations

Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

2002 • 447 citations

Skeletal defects in VEGF120/120 mice reveal multiple roles for VEGF in skeletogenesis

2002 • 440 citations

gridlock , an HLH Gene Required for Assembly of the Aorta in Zebrafish

2000 • 427 citations

VEGFA is necessary for chondrocyte survival during bone development

2004 • 390 citations

Role of VEGF-A in Vascularization of Pancreatic Islets

2003 • 386 citations

Formation of the digestive system in zebrafish. I. liver morphogenesis

2003 • 362 citations

Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities

2004 • 345 citations

Vascular endothelial growth factor (VEGF) directly enhances osteoclastic bone resorption and survival of mature osteoclasts

2000 • 345 citations

CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo

2003 • 326 citations

Vascular endothelial growth factor stimulates skeletal muscle regeneration in Vivo

2004 • 321 citations

Vessel Patterning in the Embryo of the Zebrafish: Guidance by Notochord

1997 • 302 citations

Embryonic vascular development: immunohistochemical identification of the origin and subsequent morphogenesis of the major vessel primordia in quail embryos

1988 • 300 citations

Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis

2003 • 294 citations

New roles for VEGF in nervous tissue?beyond blood vessels

2004 • 288 citations

Human bone marrow microvascular endothelial cells support long-term proliferation and differentiation of myeloid and megakaryocytic progenitors

1995 • 285 citations

Multiple Developmental Roles of VEGF Suggested by a LacZ-Tagged Allele

1999 • 284 citations

Liver development update: new embryo models, cell lineage control, and morphogenesis

2004 • 282 citations

Formation of the digestive system in zebrafish. ii. pancreas morphogenesis☆

2003 • 281 citations

Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling

2003 • 267 citations

VEGF mediates angioblast migration during development of the dorsal aorta in Xenopus

1998 • 261 citations

Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a

2004 • 261 citations

Combinatorial effects ofFlk1andTal1on vascular and hematopoietic development in the mouse

2003 • 251 citations

Stimulation and inhibition of angiogenesis by placental proliferin and proliferin-related protein

1994 • 244 citations

Soluble VEGF isoforms are essential for establishingepiphyseal vascularization and regulating chondrocyte development and survival

2004 • 237 citations

Plasticity of endothelial cells during arterial-venous differentiation in the avian embryo

2001 • 235 citations

VEGF: a critical player in neurodegeneration

2004 • 233 citations

Soluble VEGF isoforms are essential for establishingepiphyseal vascularization and regulating chondrocyte development and survival

2004 • 226 citations

The role of vascular endothelial growth factor (VEGF) in vasculogenesis, angiogenesis, and hematopoiesis in zebrafish development

2001 • 221 citations

Hedgehog signaling is essential for endothelial tube formation during vasculogenesis

2004 • 207 citations

The VEGF receptor flt-1 (VEGFR-1) is a positive modulator of vascular sprout formation and branching morphogenesis

2004 • 205 citations

Signaling Pathways in Vascular Development

2002 • 194 citations

Lineage analysis of the hemangioblast as defined by FLK1 and SCL expression

2002 • 183 citations

Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve

2004 • 180 citations

Role of pericytes in vascular morphogenesis

2005 • 157 citations

The neural tube patterns vessels developmentally using the VEGF signaling pathway

2004 • 152 citations

Hypoxia affects mesoderm and enhances hemangioblast specification during early development

2004 • 147 citations

Hematopoietic stem cell repopulating ability can be maintained in vitro by some primary endothelial cells

2004 • 146 citations

Recent advances in angiogenesis, anti-angiogenesis and vascular targeting

2002 • 133 citations

Dynamic in vivo imaging of postimplantation mammalian embryos using whole embryo culture

2002 • 122 citations

Recombination signal sequence-binding protein Jκ alters mesodermal cell fate decisions by suppressing cardiomyogenesis

2003 • 121 citations

Notochord Patterning of the Endoderm

2001 • 113 citations

Loss of the VEGF164 and VEGF188 Isoforms Impairs Postnatal Glomerular Angiogenesis and Renal Arteriogenesis in Mice

2002 • 109 citations

Developmental Signalling: Vertebrate ligands for Notch

1995 • 107 citations

A role for notochord in axial vascular development revealed by analysis of phenotype and the expression of VEGR-2 in zebrafish flh and ntl mutant embryos

1997 • 99 citations

Negative Regulation of Midline Vascular Development by the Notochord

2004 • 95 citations

Allocation and Early Differentiation of Cardiovascular Progenitors in the Mouse Embryo

2001 • 88 citations

Cell Fate Decisions in Early Blood Vessel Formation

2003 • 83 citations

Trophoblast expression of fms-like tyrosine kinase 1 is not required for the establishment of the maternal–fetal interface in the mouse placenta

2003 • 75 citations

BMP4 and noggin control embryonic blood vessel formation by antagonistic regulation of VEGFR-2 (Quek1) expression

2005 • 74 citations

Interdependent development of blood vessels and organs

2003 • 65 citations

Segregation of arterial and venous markers in subpopulations of blood islands before vessel formation

2005 • 64 citations

Angiogenesis within the developing mouse neural tube is dependent on sonic hedgehog signaling: possible roles of motor neurons

2005 • 54 citations

Blood Vessel Patterning at the Embryonic Midline

2004 • 54 citations