Evaluation of the Potential Role of Cytokines in Toxic Epidermal Necrolysis

A novel method for real time quantitative RT-PCR.

1996 • 2,093 citations

The LightCycler ^TM : A Microvolume Multisample Fluorimeter with Rapid Temperature Control

1997 • 908 citations

Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin

1999 • 867 citations

Identification and induction of keratinocyte-derived IL-10.

1992 • 342 citations

Drug Specific Cytotoxic T-Cells in the Skin Lesions of a Patient with Toxic Epidermal Necrolysis

2002 • 297 citations

Apoptosis as a mechanism of keratinocyte death in toxic epidermal necrolysis

1996 • 293 citations

Production of IL-18 (IFN-gamma-inducing factor) messenger RNA and functional protein by murine keratinocytes.

1997 • 267 citations

Delayed reactions to drugs show levels of perforin, granzyme B, and Fas-L to be related to disease severity

2002 • 241 citations

Alloreactive murine CD8+ T cell clones secrete the Th1 pattern of cytokines.

1990 • 240 citations

Toxic epidermal necrolysis (the scalded skin syndrome): A reappraisal

1979 • 232 citations

Functional Characterization of Human IL-10

1992 • 201 citations

Infiltration of cytotoxic T cells in drug‐induced cutaneous eruptions

2000 • 185 citations

Expression of Fas Antigen on Keratinocytes In Vivo and Induction of Apoptosis in Cultured Keratinocytes

1994 • 175 citations

Cutaneous T-cell recruitment in toxic epidermal necrolysis. Further evidence of CD8+ lymphocyte involvement

1993 • 170 citations

Blister fluid T lymphocytes during toxic epidermal necrolysis are functional cytotoxic cells which express human natural killer (NK) inhibitory receptors

2000 • 166 citations

T‐cell‐mediated cytotoxicity against keratinocytes in sulfamethoxazol‐induced skin reaction

1998 • 145 citations

Toxic epidermal necrolysis

1998 • 138 citations

Serial Cultivation of Single Keratinocytes from the Outer Root Sheath of Human Scalp Hair Follicles

1986 • 130 citations

Cutaneous T-Cell Recruitment in Toxic Epidermal Necrolysis

1993 • 128 citations

T-Cell Subsets in Drug-Induced Toxic Epidermal Necrolysis

1991 • 120 citations

Crosstalk Between Keratinocytes and T Lymphocytes via Fas/Fas Ligand Interaction: Modulation by Cytokines

1999 • 95 citations

Acquisition of granzyme B and Fas ligand proteins by human keratinocytes contributes to epidermal cell defense.

1997 • 95 citations

Increased interleukin 10, tumor necrosis factor α, and interleukin 6 levels in blister fluid of toxic epidermal necrolysis

2002 • 77 citations

Intracellular Localization of Keratinocyte Fas Ligand Explains Lack of Cytolytic Activity under Physiological Conditions

2003 • 75 citations

Apoptosis and Accidental Cell Death in Cultured Human Keratinocytes after Thermal Injury

1998 • 60 citations

T-cell Subsets in Drug-Induced Toxic Epidermal Necrolysis

1992 • 38 citations

Increased expression of Fas on human epidermal cells after in vivo exposure to single-dose ultraviolet (UV) B or long-wave UVA radiation

2002 • 33 citations

Soluble fractions of tumor necrosis factor-alpha, interleukin-6 and of their receptors in toxic epidermal necrolysis: a comparison with second-degree burns.

1998 • 31 citations

Keratinocyte injury in drug-induced toxic epidermal necrolysis: Simultaneous but distinct topographic expression of CD95R and calprotectin

2002 • 28 citations

Allogeneic T cell activation triggering by MHC class I antigens.

1988 • 21 citations

The "looped oligo" method for generating reference molecules for quantitative PCR.

1994 • 17 citations