Drug Specific Cytotoxic T-Cells in the Skin Lesions of a Patient with Toxic Epidermal Necrolysis

Severe Adverse Cutaneous Reactions to Drugs

1994 • 1,523 citations

Medication Use and the Risk of Stevens–Johnson Syndrome or Toxic Epidermal Necrolysis

1995 • 1,415 citations

Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin

1999 • 867 citations

Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine.

1995 • 351 citations

Idiosyncratic drug reactions: the reactive metabolite syndromes

2000 • 329 citations

Apoptosis as a mechanism of keratinocyte death in toxic epidermal necrolysis

1996 • 293 citations

The HLA-A,B "negative" mutant cell line C1R expresses a novel HLA-B35 allele, which also has a point mutation in the translation initiation codon.

1992 • 290 citations

Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones.

1997 • 279 citations

Cutting Edge: Cytolytic Effector Function in Human Circulating CD8+ T Cells Closely Correlates with CD56 Surface Expression

2000 • 263 citations

CD8+ T cells in psoriatic lesions preferentially use T-cell receptor V beta 3 and/or V beta 13.1 genes.

1994 • 233 citations

Toxic epidermal necrolysis (the scalded skin syndrome): A reappraisal

1979 • 232 citations

Clonal transformation of adult human leukocytes by Epstein-Barr virus

1977 • 213 citations

Recognition of Sulfamethoxazole and Its Reactive Metabolites by Drug-Specific CD4+ T Cells from Allergic Individuals

2000 • 212 citations

Cutaneous T-cell recruitment in toxic epidermal necrolysis. Further evidence of CD8+ lymphocyte involvement

1993 • 170 citations

Blister fluid T lymphocytes during toxic epidermal necrolysis are functional cytotoxic cells which express human natural killer (NK) inhibitory receptors

2000 • 166 citations

T‐cell‐mediated cytotoxicity against keratinocytes in sulfamethoxazol‐induced skin reaction

1998 • 145 citations

Toxic epidermal necrolysis

1998 • 138 citations

Cutaneous T-Cell Recruitment in Toxic Epidermal Necrolysis

1993 • 128 citations

CD8+ dermal T cells from a sulphamethoxazole-induced bullous exanthem proliferate in response to drug-modified liver microsomes

2006 • 98 citations

Anticonvulsant-induced toxic epidermal necrolysis: Monitoring the immunologic response

2000 • 96 citations

T Cells Isolated from Positive Epicutaneous Test Reactions to Amoxicillin and Ceftriaxone are Drug Specific and Cytotoxic

2000 • 90 citations

Dominant T-cell-receptor beta chain variable region V beta 14+ clones in juvenile rheumatoid arthritis.

1993 • 68 citations